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    An AI Overview is not available for this searchCan't generate an AI overview right now. Try again later.
    AI Overview
    Quaternium-73 (often known as Pionine) is a highly effective, safe antibacterial and antifungal agent used in cosmetics and skincare to treat acne, specifically targeting Propionibacterium acnes. It is effective at extremely low concentrations (
    0.0001
    %
    --
    0.001
    %
    ), often functioning as both a preservative and an active ingredient to prevent pimples, reduce acne marks, and inhibit melanin formation. 
    Key Features and Benefits 
    • Strong Antibacterial/Antifungal Action: Inhibits Propionibacterium and various fungi at low concentrations, acting as a superior preservative to parabens.
    • Acne Treatment: Frequently used in Japanese skincare, such as in this example from M.C.Biotec and this acne treatment ingredient list to treat acne, prevent scarring, and reduce dark spots by reducing sebum-related bacteria.
    • Melanin Inhibition: Studies suggest it can inhibit 50% of melanin formation at a concentration of 0.000003%.
    • Stability: It is a yellow, odorless powder with good heat and light stability, ensuring long-term effectiveness, notes this article about its role as a preservative.
    • Safety: It has a low irritation risk for the skin and eyes, and is safe for long-term use. 
    Usage Guidelines 
    • Application Areas: Acne creams, cleansers, toners, lotions, and anti-dandruff shampoos.
    • Concentration: Typically used in concentrations from 0.0001% to 0.001%, with higher concentrations sometimes causing irritation.
    • Storage: Products should be stored in light-proof containers in a cool, dark place. 
    Commonly available from suppliers like COSROMA and Coachchem, this ingredient is highly regarded for its efficacy in modern, gentle, and effective antibacterial formulations, as detailed in this review of its uses. 
    • Quaternium-73
      Oct 24, 2025 — Quaternium-73 has the following benefits: * **Antibacterial** Fights acne and blemishes * **Anti-static** Prevents static buildup ...
      SpecialChem
    • Quaternium-73-Anti-acne & Anti-psoriasis - M.C.Biotec
      Liquid achromobacter sp 0.001 Absidia orchidis 0.0001. Enterobacteriaceae 0.01 Tinea capitis fungus 0.001. Botulinum toxin 0.005 B...
      M.C.Biotec
    • Quaternium-73 has very strong antibacterial activity and can ...
      Quaternium-73, also known as Pionine, is a highly effective antibacterial ingredient commonly used in Japanese over-the-counter (O...
      Drop(Nanjing)Bio-Tech Co.,Ltd.
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    Web results

    Quaternium-73 by COSROMA - Personal Care & Cosmetics


    UL Prospector
    https://www.ulprospector.com › PersonalCare › Detail
    UL Prospector
    https://www.ulprospector.com › PersonalCare › Detail
    Quaternium-73 has an inhibiting effect on bacteria and a variety of fungi at a low concentration. Particularly, Quaternium-73 has a strong anti-bacterial effect ...Read more

    Quaternium-73: A Versatile Antimicrobial Agent for Modern ...


    ChemicalBook
    https://www.chemicalbook.com › article › quaternium-...
    ChemicalBook
    https://www.chemicalbook.com › article › quaternium-...
    Dec 31, 2024 — Quaternium-73 (Pyrithione) can be used for the treatment of acne, pimples, etc., and has important applications in the cosmetics field as a conditioner, ...Read more
    Missing: antibacterial ‎| Show results with: antibacterial

    Quaternium-73-Anti-acne & Anti-psoriasis


    M.C.Biotec
    http://www.mcbiotec.com › ...
    M.C.Biotec
    http://www.mcbiotec.com › ...
    1. ANTIBACTERIAL ACTIVITY. Quaternium-73 shows extremely strong antibacterial activity at very low concentration. · 2. STRONG INHIBITION OF MELANIN‍‍‍‍‍‍‍‍‍‍‍‍‍‍.Read more

    Quaternium-73


    SpecialChem
    https://www.specialchem.com › Cosmetics › INCI names
    SpecialChem
    https://www.specialchem.com › Cosmetics › INCI names
    Oct 24, 2025 — Quaternium-73 is a potent synthetic preservative with antimicrobial and antistatic benefits. It helps keep acne and dandruff under control ...Read more

    CAS 15763-48-1 (Quaternium 73)


    BOC Sciences
    https://www.bocsci.com › ... › Cosmetic Ingredients
    BOC Sciences
    https://www.bocsci.com › ... › Cosmetic Ingredients
    Quaternium-73 has excellent antistatic, bactericidal, antibacterial, antiseptic, emulsifying, dispersing, solubilizing, and corrosion-inhibiting properties.
    $199.00 · Free delivery · 30-day returns
    People also ask
    What is Quaternium 73 used for?
    It is a safe long-term fungicide that kills bacteria and various fungi at lower concentrations (2 parts per 100,000) and improves acne, pimples, and polyacne symptoms. Quaternium 73 is an antibacterial agent used as a preservative in cosmetics.

    CAS 15763-48-1 (Quaternium 73) - BOC Sciences


    BOC Sciences
    https://www.bocsci.com › ... › Cosmetic Ingredients
    BOC Sciences
    https://www.bocsci.com › ... › Cosmetic Ingredients
    Is polyquaternium 73 safe?
    Polyquaternium-73 is considered to be highly safe and non-irritant for use in cosmetics and personal care products.Apr 21, 2023

    Polyquaternium-73 - Cosmetic Ingredient INCI - SpecialChem


    SpecialChem
    https://www.specialchem.com › cosmetics › polyquaterni...
    SpecialChem
    https://www.specialchem.com › cosmetics › polyquaterni...
    What skincare ingredients are antibacterial?
    An error has occurred. Please try again later.
    Is benzalkonium chloride 0.13 antibacterial?
    Label: ANTIBACTERIAL- benzalkonium chloride 0.13% liquid.

    ANTIBACTERIAL- benzalkonium chloride 0.13% liquid - DailyMed


    DailyMed - NIH
    https://dailymed.nlm.nih.gov › dailymed › drugInfo
    DailyMed - NIH
    https://dailymed.nlm.nih.gov › dailymed › drugInfo

    Web results

    Quaternium-73 and Octyl Methoxycinnamate - Creative Biogene


    microbialtec.com
    https://www.microbialtec.com › quaternium-73-and-oct...
    microbialtec.com
    https://www.microbialtec.com › quaternium-73-and-oct...
    Quaternium-73 is a new and safe anti-bacterial ingredient. Ethylhexyl methoxycinnamate is an UV protection agent. This complex can kill all kinds of bacteria ...Read more

    Quaternium-73 (and) Butylene Glycol - Anallerg


    anallergactives.com
    https://www.anallergactives.com › products › quaternium...
    anallergactives.com
    https://www.anallergactives.com › products › quaternium...
    Particularly, Quaternium-73 has strong anti-bacterial effect on Propionibacterium, it can improve the symptoms of acne and frequently occurring acne. In ...Read more
    5.0(1)

    QUATERNIUM-73 by Shanghai Coachchem Technology ...


    UL Prospector
    https://www.ulprospector.com › PersonalCare › Detail
    UL Prospector
    https://www.ulprospector.com › PersonalCare › Detail
    QUATERNIUM-73 is a safe and long-term use antimicrobial agent that exhibits antimicrobial effects against bacteria and various fungi at low concentrations.Read more

    What is Quaternium 73 Used For In Cosmetics - Chenlang


    CHEN LANG BIO TECH
    https://www.chenlangbio.com › knowledge › what-is-q...
    CHEN LANG BIO TECH
    https://www.chenlangbio.com › knowledge › what-is-q...
    May 24, 2024 — Derived from rigorous chemical synthesis, this compound exhibits exceptional conditioning and antimicrobial properties, rendering it ...Read more

    Quaternium-73 has very strong antibacterial activity and ...


    Drop(Nanjing)Bio-Tech Co.,Ltd.
    https://www.drop-bio.com › quaternium-73-has-very-str...
    Drop(Nanjing)Bio-Tech Co.,Ltd.
    https://www.drop-bio.com › quaternium-73-has-very-str...
    Quaternium-73, also known as Pionine, is a highly effective antibacterial ingredient commonly used in Japanese over-the-counter (OTC) acne treatment products, ...Read more
    People also search for
    Quaternium 73 antibacterial side effects
    Quaternium 73 antibacterial ingredients
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