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AI Overview

Cooling agent WS-3 (N-Ethyl-p-menthane-3-carboxamide) is a widely used, high-purity, white crystalline powder known for providing a strong, immediate, and long-lasting cooling sensation (30+ minutes) without the bitter, medicinal taste of menthol. It is a menthol derivative (CAS # 39711-79-0) that is virtually odorless and tasteless, making it ideal for adding a "fresh" or "icy" impact to flavors in chewing gum, candies, beverages, and oral care products without affecting the primary flavor profile.

Key Characteristics and Benefits

Intensity: WS-3 offers a cooling potency roughly 1.5 times stronger than menthol, providing a sharp "ice-like" burst.
Sensation Profile: It typically hits the roof of the mouth and back of the tongue, offering a clean, immediate sensation.
Stability: It is highly stable, maintaining its cooling strength even at high processing temperatures (up to 200°C).
Neutral Flavor: Unlike menthol, it has minimal flavor impact, allowing the intended flavor (e.g., fruit, herbal) to remain prominent.
Solubility: It is insoluble in water but soluble in alcohols and propylene glycol (PG), making it suitable for flavor concentrates.

Typical Applications

Food & Confectionery: Chewing gum, hard candies, mints, chocolates, and dairy products (ice cream/yogurt).
Beverages: Energy drinks, cocktails, and soft drinks to add a crisp, refreshing note.
Oral Care & Personal Care: Toothpaste, mouthwash, lip balm, and skin creams/lotions.
Other: Vaping liquids (e-liquids) and cigarettes.

Recommended Usage

Dosage: Generally used in concentrations of 0.5%–1.5%, though it varies based on application (e.g., 10-100 mg/kg in drinks; 500-2000 mg/kg in gum).
Usage Tip: To avoid bitterness at higher concentrations, it can be combined with sweeteners or other cooling agents like WS-23 for a more balanced effect.

Web results

WS-3 Cooling Agent: Applications, Benefits, and ...

Anhui Chinaherb Flavors&Fragrances Co.,Ltd.

https://www.cnherbflavor.com › blog › ws-3-cooling-ag...

Anhui Chinaherb Flavors&Fragrances Co.,Ltd.

https://www.cnherbflavor.com › blog › ws-3-cooling-ag...

May 9, 2025 — WS-3 is a synthetic cooling compound developed to provide a stronger cooling impact than traditional menthol.Read more

Discussions and forums

Can someone recommend a cooling Agent?

Reddit ·

r/DIY_eJuice

· 30+ comments

· 5 years ago

Can someone recommend a cooling Agent?

Reddit ·

r/DIY_eJuice

· 30+ comments

· 5 years ago

In light of the few post asking about menthol and other cooling agents

Reddit ·

r/DIY_eJuice

· 20+ comments

· 9 years ago

In light of the few post asking about menthol and other cooling agents

Reddit ·

r/DIY_eJuice

· 20+ comments

· 9 years ago

Web results

Cooling Agent WS-3

Alfa Chemistry

https://ffc.alfa-chemistry.com › ... › Cooling Agents

Alfa Chemistry

https://ffc.alfa-chemistry.com › ... › Cooling Agents

Has a strong cool flavor activity, no menthol bitter, spicy feeling, no burning, numbness and other effects, can produce impact, fresh, longer aroma. Has a long ...Read more

Cooling Agents WS-3

Foreverest Resources Ltd

https://foreverest.net › Other Specialty Chemicals

Foreverest Resources Ltd

https://foreverest.net › Other Specialty Chemicals

It produces an immediate, clean cooling effect, and at an aroma concentration of 10%, it is almost odourless, showing only a faint alcoholic and cooling note.Read more

The role of synthetic coolants, WS-3 and WS-23, in ...

ScienceDirect.com

https://www.sciencedirect.com › science › article › pii

ScienceDirect.com

https://www.sciencedirect.com › science › article › pii

by S Yogeswaran2022Cited by 20 — Synthetic cooling agents (WS-23 and WS-3) provide a cooling sensation. Coolants in e-cigarettes modify acellular and ROS levels in lung epithelial cells.Read more

WS3

Anshul Specialty Molecules Private Limited

https://www.anshulchemicals.com › ws3

Anshul Specialty Molecules Private Limited

https://www.anshulchemicals.com › ws3

211.34. ws3. MSDS. Here are the applications of WS-3 cooling agent: 1. Food & Beverages. Chewing gum, candies, and mints for a long-lasting cooling effect.Read more

WS-23, WS-5, WS-12, WS-3 vs Menthol for Food & Beverage

TasteNest

https://www.tastenest.com.au › post › cooling-agents-ws...

TasteNest

https://www.tastenest.com.au › post › cooling-agents-ws...

Aug 6, 2025 — The WS-series (short for Water Soluble) cooling agents are synthetic, odourless, flavourless compounds that also activate cold receptors—but ...Read more

Cooling Agent Hierarchy: WS-3 vs. WS-5 vs. WS-23 Usage ...

Cuiguai

https://www.cuiguai.com › cooling-agent-hierarchy-whe...

Cuiguai

https://www.cuiguai.com › cooling-agent-hierarchy-whe...

Jan 10, 2026 — WS-3 simulates this bite in the throat. A Cola flavor with only WS-23 feels “flat.” A Cola flavor with a touch of WS-3 feels “fizzy.Read more

WS-23 vs WS-12 vs WS-3: The Ultimate Cooling Agent ...

Xi'an Taima Biological Engineering Co. Ltd

https://www.taimacn.com › new › ws23-vs-ws12-vs-ws3-...

Xi'an Taima Biological Engineering Co. Ltd

https://www.taimacn.com › new › ws23-vs-ws12-vs-ws3-...

Apr 18, 2026 — Q: Will cooling agents mute my fruit flavors? A: Unlike menthol, WS series agents do not mute flavors. In fact, when dosed correctly ...Read more

Web results

Cooling Agent WS-3 1KG/BAG

Hangzhou Crossing Ocean Biotech Co.,Ltd

https://www.crossingoceanbiotech.com › display-83-133

Hangzhou Crossing Ocean Biotech Co.,Ltd

https://www.crossingoceanbiotech.com › display-83-133

Cooling Agent WS-3 1KG/BAG ; Appearance. White crystalline solid. Confirm ; Aroma. Slight odor of mint. Confirm ; Melting point. 91~98℃. 97.5℃ ; Purity. ≥99.0%.Read more

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