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    An AI Overview is not available for this searchCan't generate an AI overview right now. Try again later.
    AI Overview
    Nifuratel intermediates are chemical compounds used in the synthesis of Nifuratel, a nitrofuran derivative used as a broad-spectrum antibacterial, antiprotozoal, and antifungal agent. These intermediates, including compounds like 5-methylmercaptomethyl-3-amino-2-oxazolidinone, are used in pharmaceutical manufacturing for producing the final active pharmaceutical ingredient (API) used in treatments for vaginal infections. 
    Key Aspects of Nifuratel Intermediate Production: 
    • Supplier Availability: Specialized chemical suppliers offer Nifuratel intermediates for research and manufacturing, such as Clearsynth and Manus Aktteva Biopharma LLP.
    • Application: These intermediates are essential for building the structure
      𝐶10
      𝐻11
      𝑁3𝑂5𝑆
      , commonly known as Nifuratel or Methylmercadone.
    • Usage Context: Nifuratel is heavily used to treat wide-spectrum vaginal infections (BV), trichomoniasis, and urinary tract infections (UTI), often marketed under brand names such as Macmiror. 
    Important Information for R&D: 
    • These products are typically designated for research, development, or analytical purposes (e.g., quality control) rather than direct clinical use. 
    Disclaimer: This information is for informational purposes only. It is not intended to provide medical advice, diagnosis, or treatment, and does not promote the use of these intermediates for any specific purpose. 
    • Nifuratel Intermediate - Clearsynth
      Clearsynth offers high quality NifuratelIntermediate compounds for analytical research, quality control and pharmaceutical develop...
      Clearsynth
    • NIFURATEL IN URINARY INFECTIONS - TYNAN - 1969
      SUMMARY. A new furan derivative, known chemically as nifuratel (Magmilor) N-(5 nitro-2-Furfurylidene) -3-Amino-5-Methylmercaptomet...
      Wiley
    • Intermediates of Nifuratel | Manufacturers | Suppliers | India
      Intermediates of Nifuratel offered by Manus Aktteva Biopharma LLP. Based on your specific request, we will source the right manufa...
      Manus Aktteva
    • Nifuratel (NF 113) | Broad-Spectrum Antibiotic | MedChemExpress
      Nifuratel (Synonyms: NF 113; SAP 113; Methylmercadone) ... Nifuratel (NF 113) is an orally active broad-spectrum antibiotic with a...
      MedchemExpress.com
    • Nifuratel - Wikipedia
      Nifuratel (brand name Macmiror, or — in combination with nystatin, — Macmiror Complex) is a drug used in gynecology. It is a local...
      Wikipedia
    • Nifuratel - an overview | ScienceDirect Topics
      Nifuratel is used to treat wide spectrum vaginal infections and it is active against BV related bacteria without affecting lactoba...
      ScienceDirect.com
    • Nifuratel: Uses, Interactions, Mechanism of Action | DrugBank
      Jun 23, 2017 — Nifuratel is a nitrofuran derivative indicated in the treatment of leucorrhea, vulvovaginal infections, and urinary tract infectio...
      DrugBank
    • Nifuratel Intermediate - Clearsynth
      Clearsynth offers high quality NifuratelIntermediate compounds for analytical research, quality control and pharmaceutical develop...
      Clearsynth
    • NIFURATEL IN URINARY INFECTIONS - TYNAN - 1969
      SUMMARY. A new furan derivative, known chemically as nifuratel (Magmilor) N-(5 nitro-2-Furfurylidene) -3-Amino-5-Methylmercaptomet...
      Wiley
    • Intermediates of Nifuratel | Manufacturers | Suppliers | India
      Intermediates of Nifuratel offered by Manus Aktteva Biopharma LLP. Based on your specific request, we will source the right manufa...
      Manus Aktteva
    Show all
    This is for informational purposes only. For medical advice or diagnosis, consult a professional. AI responses may include mistakes. Learn more
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    Web results

    What is the mechanism of Nifuratel?


    Patsnap Synapse
    https://synapse.patsnap.com › article › what-is-the-mecha...
    Patsnap Synapse
    https://synapse.patsnap.com › article › what-is-the-mecha...
    Jul 17, 2024 — One of the primary mechanisms of Nifuratel is its ability to interfere with the nucleic acid synthesis of microorganisms. Nifuratel undergoes ...Read more

    Nifuratel - an overview


    ScienceDirect.com
    https://www.sciencedirect.com › topics › nifuratel
    ScienceDirect.com
    https://www.sciencedirect.com › topics › nifuratel
    Nifuratel is used to treat wide spectrum vaginal infections and it is active against BV related bacteria without affecting lactobacilli (Polatii, 2012; Togni et ...Read more

    Intermediates of Nifuratel | Manufacturers | Suppliers | India


    Manus Aktteva
    https://www.manusaktteva.com › IntermediatesOf › Nifu...
    Manus Aktteva
    https://www.manusaktteva.com › IntermediatesOf › Nifu...
    Intermediates of Nifuratel offered by Manus Aktteva Biopharma LLP. Based on your specific request, we will source the right manufacturer / supplier ...

    Nifuratel: Uses, Interactions, Mechanism of Action


    DrugBank
    https://go.drugbank.com › drugs
    DrugBank
    https://go.drugbank.com › drugs
    Jun 23, 2017 — Nifuratel is a nitrofuran derivative indicated in the treatment of leucorrhea, vulvovaginal infections, and urinary tract infections.
    Missing: INTERMEDIATE ‎| Show results with: INTERMEDIATE
    People also ask
    Is nifuratel an antibiotic?
    Nifuratel (NF 113) is an orally active broad-spectrum antibiotic with antiprotozoal, antibacterial, anticancer and anti-inflammatory activities, and has good inhibitory effects on Candida and Trichomonas.

    Nifuratel (NF 113) | Broad-Spectrum Antibiotic - MedchemExpress.com


    MedchemExpress.com
    https://www.medchemexpress.com › nifuratel
    MedchemExpress.com
    https://www.medchemexpress.com › nifuratel
    What is the mode of action of nifuratel?
    Studies of the mechanism of action of nifuratel indicated that it acts by inhibiting the constitutive and interleukin-6-induced STAT3 activation. Taken together, our findings demonstrate that nifuratel may be a novel, clinically accessible STAT3 inhibitor in gastric cancer cells.

    Nifuratel, a novel STAT3 inhibitor with potent activity against human ... - PMC


    PMC - NIH
    https://pmc.ncbi.nlm.nih.gov › articles › PMC5677376
    PMC - NIH
    https://pmc.ncbi.nlm.nih.gov › articles › PMC5677376
    What is nifuratel Nystatin combination?
    Nifuratel‐nystatin combination is a wide spectrum antimicrobial agent used for treatment of mixed vaginal infections caused by at least two of the triad pathogens (fungi, bacteria, and T. vaginalis) (Cepický 2003).

    Nifuratel‐Nystatin combination for the treatment of mixed ...


    PubMed Central (PMC) (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC6494476
    PubMed Central (PMC) (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC6494476
    Is macmiror complex an antibiotic?
    Each vaginal soft capsule contains a combination of nifuratel (500 mg), a powerful antibacterial and antiprotozoan , and nystatin (200,000 IU), an effective antifungal active against Candida .

    Macmiror Complex 500 mg + 200 000 IU 12 soft capsules vaginal infections


    Farmacia Dottor Tili
    https://www.dottortili.com › products › macmiror-compl...
    Farmacia Dottor Tili
    https://www.dottortili.com › products › macmiror-compl...

    Web results

    Nifuratel‐Nystatin combination for the treatment of mixed ...


    PubMed Central (PMC) (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC6494476
    PubMed Central (PMC) (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC6494476
    by J Obiero · 2018 · Cited by 18 — To assess the effectiveness and safety of nifuratel‐nystatin combination for the treatment of mixed infections of bacterial vaginosis, vulvovaginal candidiasis ...Read more

    Nifuratel


    Wikipedia
    https://en.wikipedia.org › wiki › Nifuratel
    Wikipedia
    https://en.wikipedia.org › wiki › Nifuratel
    Nifuratel is a drug used in gynecology. It is a local antiprotozoal and antifungal agent that may also be given orally. Nifuratel is not approved for use in ...Read more
    Missing: INTERMEDIATE ‎| Show results with: INTERMEDIATE

    Nifuratel Intermediate


    Clearsynth
    https://clearsynth.com › listing › api=Nifuratel
    Clearsynth
    https://clearsynth.com › listing › api=Nifuratel
    Clearsynth offers high quality NifuratelIntermediate compounds for analytical research, quality control and pharmaceutical development. Browse available ...Read more

    Nifuratel Intermediate 14359-97-8 - Sinoway


    china-sinoway.com
    https://www.china-sinoway.com › nifuratel-intermediate...
    china-sinoway.com
    https://www.china-sinoway.com › nifuratel-intermediate...
    Nifuratel indications for the treatment of vulvar, vaginal infections and vaginal discharge and urinary tract infections caused by bacteria, trichomoniasis, ...Read more

    Drug repurposing of Nifuratel against methicillin-resistant ...


    Frontiers
    https://www.frontiersin.org › fcimb.2025.1738031 › full
    Frontiers
    https://www.frontiersin.org › fcimb.2025.1738031 › full
    by P She · 2025 — In vivo, Nifuratel treatment significantly reduced bacterial loads, attenuated inflammation, and promoted wound healing comparably to fusidic acid. The compound ...Read more

    CN101037434A - Production method of nifuratel


    Google Patents
    https://patents.google.com › patent
    Google Patents
    https://patents.google.com › patent
    The method makes use of thiourea as initial material to produce nifuratel. The improvement is that it is no longer to use methyl mercaptan or methomyl in the ...Read more
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