Filters and Topics
Search Results
AI Overview
Key Properties & Uses
- Amphiphilic Nature: Hydrophilic mPEG block creates a stabilizing outer layer, while the hydrophobic-prone PGA block forms the core, ideal for encapsulating hydrophobic drugs.
- Micelle Formation: Self-assembles in water into spherical micelles (50-100 nm) for drug delivery.
- Drug Conjugation: The free carboxyl groups on the PGA block allow for covalent drug attachment, creating prodrugs or enhancing drug loading.
- Biocompatibility: PGA is a natural amino acid polymer, making mPEG-b-PGA non-toxic, non-immunogenic, and biodegradable.
- Applications:
- Chemotherapy: Encapsulates anticancer drugs (e.g., cisplatin, doxorubicin) for targeted delivery, reducing systemic toxicity.
- Controlled Release: Provides sustained drug release in the tumor microenvironment.
- Tissue Engineering: Used in multilayer films with chitosan to reduce cell adhesion.
- Hypoxia-Responsive Systems: Modified versions can release drugs faster in low-oxygen tumor areas.
Show all
Show more
block-poly(glutamic Acid) [mPEG-P(Glu)] Manufacturer
SINOPEG
https://www.sinopeg.com › Polymeric Micelle
SINOPEG
https://www.sinopeg.com › Polymeric Micelle
Methoxypoly(ethylene glycol)-block-poly(glutamic acid). SINOPEG Biotech provides block copolymer derived from hydrophilic PEG and hydrophobic ...
block-poly(L-glutamic acid sodium salt)
Alamanda Polymers
https://www.alamanda-polymers.com › methoxy-polyeth...
Alamanda Polymers
https://www.alamanda-polymers.com › methoxy-polyeth...
Methoxy-poly(ethylene glycol)-block-poly(L-glutamic acid sodium salt) is a linear hydrophilic block copolymer which has a poly(L-glutamic acid sodium salt) ...
mPEG-PGlu - CD Bioparticles
cd-bioparticles.net
https://www.cd-bioparticles.net › mpeg-pglu
cd-bioparticles.net
https://www.cd-bioparticles.net › mpeg-pglu
Methoxy-poly(ethylene glycol)-block-poly(L-glutamic acid) (mPEG-pGlu) is a linear PEG-poly(L-Amino Acid) block copolymer which can be self assembled into ...
$920.00In stock$80 delivery
Methoxypoly(ethylene glycol)-block-poly(glutamic acid) [mPEG-P ...
Amerigo Scientific
https://www.amerigoscientific.com › methoxypolyethyl...
Amerigo Scientific
https://www.amerigoscientific.com › methoxypolyethyl...
Amerigo Scientific is a specialist distributor in serving life science that provides high quality Methoxypoly(ethylene glycol)-block-poly(glutamic acid) ...
mPEG-b-PGA - Ruixibiotech
Xi'an ruixi Biological Technology Co
https://www.ruixibiotech.com › pts › mpeg-b-pga
Xi'an ruixi Biological Technology Co
https://www.ruixibiotech.com › pts › mpeg-b-pga
mPEG-b-PGA,Methoxy-poly(ethyleneglycol)-block-poly(L-glutamic acid) is a linear AB amphiphilic block copolymerconsisting of a hydrophilic block polyethylene ...
Methoxypoly(ethylene glycol)-block-poly(L-glutamic acid)- ...
National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
by W Song2012Cited by 103 — CDDP is loaded into methoxypoly(ethylene glycol)-block-poly(L-glutamic acid) (mPEG-b-PLG), and a combination with iRGD is applied for NSCLC chemotherapy.
block-poly(glutamic Acid) [mPEG-P(Glu)40] Manufacturer
SINOPEG
https://www.sinopeg.com › methoxypoly-ethylene-glyc...
SINOPEG
https://www.sinopeg.com › methoxypoly-ethylene-glyc...
Methoxypoly(ethylene glycol)-block-poly(glutamic acid) is available with molecular weight 2K, 5K, 10K, 20K and 40K Da, other M.W. may be available by custom ...
block-poly (glutamic acid)-graft-6-(2-nitroimidazole) hexyl ...
Taylor & Francis Online
https://www.tandfonline.com › ... › Volume 27, Issue 1
Taylor & Francis Online
https://www.tandfonline.com › ... › Volume 27, Issue 1
by Z Ahmad2016Cited by 43 — Methoxypoly(ethylene glycol)-block-poly(L-glutamic acid)-loaded cisplatin and a combination with iRGD for the treatment of non-small-cell lung cancers ...
block-poly(L-glutamic acid sodium salt)
Alamanda Polymers
https://www.alamanda-polymers.com › methoxy-polyeth...
Alamanda Polymers
https://www.alamanda-polymers.com › methoxy-polyeth...
Methoxy-poly(ethylene glycol)-block-poly(L-glutamic acid sodium salt) · x=25 (poly-L-glutamic acid sodium salt, MW=3,800 Da) · x=40 (poly-L-glutamic acid sodium ...
Methoxypoly(ethylene glycol)‐block‐Poly(L‐glutamic acid) ...
Wiley Online Library
https://onlinelibrary.wiley.com › abs › mabi.201200145
Wiley Online Library
https://onlinelibrary.wiley.com › abs › mabi.201200145
by W Song2012Cited by 103 — CDDP is loaded into methoxypoly(ethylene glycol)-block-poly(L-glutamic acid) (mPEG-b-PLG), and a combination with iRGD is applied for NSCLC ...