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    AI Overview
    Bis(2,4,4-trimethylpentyl) phosphinic acid, commonly known as
    Cyanex 272, is a high-selectivity organophosphinic acid solvent extraction agent used in hydrometallurgy, primarily for separating cobalt from nickel and extracting rare earth elements (REEs). It acts as a liquid-liquid chelating agent, often used at 0.1%–5% concentrations with diluents like kerosene, offering high efficiency for heavy rare earth elements and transition metals. 
    Key Applications and Properties 
    • Cobalt/Nickel Separation: Known for exceptional selectivity, Cyanex 272 can separate cobalt from nickel, even in the presence of impurities like Calcium (Ca).
    • Rare Earth Element (REE) Separation: Efficiently used for the purification and extraction of heavy REEs from various solutions.
    • Industrial Metal Removal: Employed to remove impurities such as zinc (Zn), manganese (Mn), and iron (Fe) from phosphoric acid and other metallurgical streams.
    • Mechanism: Functions as a cation exchanger, forming stable, hydrophobic metal-ligand complexes in the organic phase.
    • pH Dependency: Extraction performance is highly dependent on pH, allowing for selective extraction by fine-tuning acidity.
    • Compatibility: Compatible with organic solvents like kerosene, diesel, and aromatic hydrocarbons. 
    Typical Industrial Use (Cyanex 272) 
    • Operating Range: Used in concentrations typically from 0.1% to 5% in organic diluents.
    • Stripping Agents: Metal ions can be stripped from the organic phase using acid solutions, such as sulfuric or hydrochloric acid.
    • Safety: Requires proper personal protective equipment (PPE), including gloves and goggles, due to potential skin and eye irritation. 
    Recent Research Trends 
    • Deep Eutectic Solvents: Research is exploring the use of Bis(2,4,4-trimethylpentyl)phosphinic acid mixed with phenol as a greener or more effective eutectic solvent for REE separation.
    • Performance: Studies show high selectivity in separating light and heavy REE subgroups. 
    • Bis(2,4,4-Trimethylpentyl)-Phosphinic Acid Cyanex 272 CAS ...
      It is also suitable for the extraction and separation of rare earth, gallium (Ga), indium (In), molybdenum (Mo), germanium (Ge), z...
      www.blitchem.com
    • Bis(2,4,4-trimethylpentyl)phosphinic acid/phenol deep eutectic ...
      Apr 1, 2025 — The goal of this work was to develop and study the physicochemical and extraction properties of a new hydrophobic deep eutectic so...
      ScienceDirect.com
    • New Eutectic Solvent Based on bis(2,4,4-trimethylpentyl ...
      Sep 3, 2025 — Previously [26,27], the authors proposed a deep eutectic solvent with a bis(2,4,4-trimethylpentyl)phosphinic acid/phenol (1:3) com...
      MDPI
    • CAS 83411-71-6 (bis-(2,4,4-Trimethylpentyl)phosphinic acid)
      Solvent extraction: Bis-(2,4,4-trimethylpentyl)phosphinic acid is widely used for the separation and purification of rare earth el...
      BOC Sciences
    • Removal of Zinc(II) and Manganese(II) from Crude Phosphoric ...
      Jan 23, 2026 — Purification of commercial phosphoric acid produced by the wet process from toxic heavy metals such as zinc and manganese is consi...
      U.S. Environmental Protection Agency (.gov)
    • Bis(2,4,4-trimethylpentyl) phosphinic acid ( ZD272/Cyanex 272
      Bis(2,4,4-trimethylpentyl) phosphinic acid (ZD272) extractanthas a high degree of selectivity for. specific metal ions, such as co...
      www.lyzhongdachem.com
    • Co-extraction of Iron and Sulfate by Bis(2,4,4-trimethylpentyl) ...
      Mar 16, 2020 — Co-extraction of Iron and Sulfate by Bis(2,4,4-trimethylpentyl)phosphinic Acid, CYANEX®272 * Innis Carson. , * Jason B. Love. , * ...
      Taylor & Francis Online
    • Bis(2,4,4-trimethylpentyl)phosphinic acid | FB32351 - Biosynth
      FB32351. Bis(2,4,4-trimethylpentyl)phosphinic acid. Write a review to earn BioPoints. Bis(2,4,4-trimethylpentyl)phosphinic acid (d...
      Biosynth
    • Bis(2,4,4-trimethylpentyl)phosphinic acid/phenol deep eutectic solvent
      Apr 1, 2025 — The solvent was completely characterized by 31P NMR, FTIR spectroscopy, and differential scanning calorimetry. The physical proper...
      ScienceDirect.com
    • Bis(2,4,4-Trimethylpentyl)-Phosphinic Acid Cyanex 272 CAS ...
      It is also suitable for the extraction and separation of rare earth, gallium (Ga), indium (In), molybdenum (Mo), germanium (Ge), z...
      www.blitchem.com
    • Bis(2,4,4-trimethylpentyl)phosphinic acid/phenol deep eutectic ...
      Apr 1, 2025 — The goal of this work was to develop and study the physicochemical and extraction properties of a new hydrophobic deep eutectic so...
      ScienceDirect.com
    • New Eutectic Solvent Based on bis(2,4,4-trimethylpentyl ...
      Sep 3, 2025 — Previously [26,27], the authors proposed a deep eutectic solvent with a bis(2,4,4-trimethylpentyl)phosphinic acid/phenol (1:3) com...
      MDPI
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    My Ad Center

    Bis(2,4,4-trimethylpentyl)phosphinic acid/phenol deep ...


    ScienceDirect.com
    https://www.sciencedirect.com › pii › S0167732225001424
    ScienceDirect.com
    https://www.sciencedirect.com › pii › S0167732225001424
    by IV Zinov’eva · 2025 · Cited by 12 — Cyanex 272 is an industrial extractant in which the content of bis(2,4,4-trimethylpentyl)phosphinic acid is 75–80 %. In order to synthesize, ...Read more
    Missing: agent ‎| Show results with: agent

    Bis(2,4,4-trimethylpentyl)phosphinic acid | 83411-71-6


    Biosynth
    https://www.biosynth.com › Research Chemicals
    Biosynth
    https://www.biosynth.com › Research Chemicals
    Bis(2,4,4-trimethylpentyl)phosphinic acid can also be used as an additive to create halogen-free flame retardant adhesives.Read more
    $355.17 · 10-day returns

    CAS 83411-71-6 (bis-(2,4,4-Trimethylpentyl)phosphinic acid)


    BOC Sciences
    https://www.bocsci.com › ... › Intermediates
    BOC Sciences
    https://www.bocsci.com › ... › Intermediates
    Solvent extraction: Bis-(2,4,4-trimethylpentyl)phosphinic acid is widely used for the separation and purification of rare earth elements. · For chelation ...Read more
    $499.00 · Free delivery · 30-day returns

    Bis(2,4,4-Trimethylpentyl)-Phosphinic Acid Cyanex 272 CAS ...


    blitchem.com
    https://www.blitchem.com › Fine Chemical
    blitchem.com
    https://www.blitchem.com › Fine Chemical
    Bis(2,4,4-Trimethylpentyl)-Phosphinic Acid Cyanex 272 is a new type of acidic phosphorus extractant with high selectivity for separation of cobalt and nickel.Read more

    EXTRACTION OF SODIUM IN BIS (2, 4,4


    Taylor & Francis Online
    https://www.tandfonline.com › ... › Volume 8, Issue 4-5
    Taylor & Francis Online
    https://www.tandfonline.com › ... › Volume 8, Issue 4-5
    by X Fu · 1990 · Cited by 43 — A study has been made of the extraction of sodium into bis (2,4,4 -trimelhylpentyl) phosphinic acid. The following basic constants were measured at 25°C using ...Read more
    Missing: agent ‎| Show results with: agent

    Bulk Bis (2 4 4-trimethylpentyl) Phosphinic Acid 83411-71-6


    Anhui Fitech Material Co.,Ltd
    https://www.fitechem.com › Chemicals
    Anhui Fitech Material Co.,Ltd
    https://www.fitechem.com › Chemicals
    ITEM, 99%, MF, C16H35O2P. Content, ≥99.0, MW, 290.42. Appearance, Colourless to light yellow viscous liquid with fruity odor, Density, 0.91—0.95g/ml.Read more

    Method for measuring bis(2,4,4-trimethylpentyl) phosphinic acid ...


    Google Patents
    https://patents.google.com › patent
    Google Patents
    https://patents.google.com › patent
    Bis(2,4,4-trimethylpentyl) phosphinic acid (IONQUEST 290) has been used as extractants in a zinc solvent extraction process for extracting only zinc and a ...

    Removal of Zinc(II) and Manganese(II) from Crude Phosphoric ...


    U.S. Environmental Protection Agency (.gov)
    https://hero.epa.gov › reference
    U.S. Environmental Protection Agency (.gov)
    https://hero.epa.gov › reference
    by NS Awwad · Cited by 11 — The commercial bis(2,4,4-trimethylpentyl)- phosphinic acid (Cyanex-272) is proposed as an extractant for the efficient removal of Zn(II) and Mn(II) from crude ...Read more

    New Eutectic Solvent Based on bis(2,4,4-trimethylpentyl) ...


    MDPI
    https://www.mdpi.com › 2227-9717
    MDPI
    https://www.mdpi.com › 2227-9717
    by TY Chikineva · 2025 — In this work, a new three-component eutectic solvent based on bis(2,4,4-trimethylpentyl)phosphinic acid (BTMPPA), tributyl phosphate (TBP) and phenol was ...Read more

    Bis(2,4,4-trimethylpentyl) phosphinic acid ( ZD272/Cyanex ...


    www.lyzhongdachem.com
    https://www.lyzhongdachem.com › Product › Phosphate
    www.lyzhongdachem.com
    https://www.lyzhongdachem.com › Product › Phosphate
    Structure: ZD272 Extraction rate with PH CAS NO 83411-71-6 Appearance Colorless to light yellow liquid Density g/cm³ (25℃) ≤0.93 Viscosity mPa.s ≤190 Flash.
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