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These are results for α,ω-Disuccinimidyl glutarate polyethylene glycol)
Search instead for α,ω-Disuccinimidyl glutaratyl poly(ethylene glycol)
Search instead for α,ω-Disuccinimidyl glutaratyl poly(ethylene glycol)
AI Overview
-Disuccinimidyl glutarate polyethylene glycol (SG-PEG-SG) is a bifunctional, amine-reactive PEG linker featuring
-hydroxysuccinimide (NHS) ester groups at both ends, connected via a hydrolytically degradable aliphatic glutarate ester linkage. Used for crosslinking, pegylation, and drug delivery, it enables rapid conjugation to lysine residues. Common molecular weights range from 2kDa to 40kDa.
Key Features and Applications:
- Structure: NHS-C3 aliphatic ester-PEG-ester C3-NHS (often referred to as SG-PEG-SG).
- Reactivity: The NHS ester groups are highly reactive toward primary amine groups () at slightly alkaline conditions (pH 7-9).
- Reversible PEGylation: The internal glutarate ester linkage is hydrolytically cleavable in aqueous environments, making it useful for projects requiring reversible PEGylation.
- Usage: Commonly used in protein-protein conjugation, peptide PEGylation, and surface modification.
- Storage: Should be kept under an inert atmosphere, at temperatures such as .
Common Molecular Weights (MW):
- 2,000 Da (2kDa)
- 5,000 Da (5kDa)
- 10,000 Da (10kDa)
- 20,000 Da (20kDa)
- 40,000 Da (40kDa)
Suppliers like SINOPEG, Creative PEGWorks, and Polymer Source offer various molecular weights of this material.
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Web results
Poly(ethylene glycol), α,ω-bis(succinimidyl glutarate)
Polymer Source
https://www.polymersource.ca › category
Polymer Source
https://www.polymersource.ca › category
Polymer Source is a premier manufacturer and supplier of high-quality research grade polymers offered to research and development communities in academia and ...Read more
Sg Peg Sg
SINOPEG
https://www.sinopeg.com › sg-peg-sg_sp
SINOPEG
https://www.sinopeg.com › sg-peg-sg_sp
α,ω-Disuccinimidyl glutaratyl poly(ethylene glycol). Molecular Weight: 5KDa, 10KDa, 20KDa, 40KDa. Package Size: 1g/bottle, 10g/bottle, 100g/bottleRead more
α,ω-Disuccinimidyl poly(ethylene glycol) [SC-PEG-SC], 2kDa
Amerigo Scientific
https://www.amerigoscientific.com › disuccinimidyl-pol...
Amerigo Scientific
https://www.amerigoscientific.com › disuccinimidyl-pol...
α,ω-Disuccinimidyl poly(ethylene glycol) [SC-PEG-SC], 2kDa. Catalog Number: PG01418530SIN. Mfr. No.: 06020202002. Price: $280. Size: 1g, 10g. Quantity:.Read more
People also ask
What is PEG in Dr Pepper?
Poly (ethylene glycol) is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers. PEG is included in many or all formulations of the soft drink Dr Pepper, purportedly as an anti-foaming agent.
Polyethylene glycol - chemeurope.com
chemeurope.com
https://www.chemeurope.com › encyclopedia › Polyethy...
chemeurope.com
https://www.chemeurope.com › encyclopedia › Polyethy...
What food has polyethylene glycol in it?
| Number | Food Category | Max Level |
|---|---|---|
| 05.3 | Chewing gum | 20,000 mg/kg |
| 11.6 | Table-top sweeteners, including those containing high-intensity sweeteners | 10,000 mg/kg |
| 13.6 | Food supplements | 70,000 mg/kg |
| 14.1.4 | Water-based flavoured drinks, including "sport," "energy," or "electrolyte" drinks and particulated drinks | 1,000 mg/kg |
GSFA Online Food Additive Details for Polyethylene glycol
fao.org
https://www.fao.org › gsfaonline › additives › details
fao.org
https://www.fao.org › gsfaonline › additives › details
Web results
Disuccinimidyl-glutarate
Sigma-Aldrich
https://www.sigmaaldrich.com › search › disuccinimidy...
Sigma-Aldrich
https://www.sigmaaldrich.com › search › disuccinimidy...
Find disuccinimidyl-glutarate and related products for scientific research at MilliporeSigma.
Missing: α, ω-
CATALOG & PRICE
Advanced Biochemicals
https://advancedbiochemicals.com › 2017/03 › A...
Advanced Biochemicals
https://advancedbiochemicals.com › 2017/03 › A...
PDF
α,ω-Disuccinimidyl poly(ethylene glycol). Catalog #. Name and MW. Price. HOP1301 ... 4-arm Poly(ethylene glycol) succinimidyl Glutarate. Catalog #. Name and ...Read more
Disuccinimidyl glutarate | C13H14N2O8 - PubChem
National Institutes of Health (.gov)
https://pubchem.ncbi.nlm.nih.gov › compound › Disuc...
National Institutes of Health (.gov)
https://pubchem.ncbi.nlm.nih.gov › compound › Disuc...
Disuccinimidyl glutarate | C13H14N2O8 | CID 4432628 - structure, chemical names, physical and chemical properties, classification, patents, literature, ...
Missing: α, ω- polyethylene glycol)
Disuccinimidyl Glutarate (DSG, CAS Number: 79642-50-5)
Cayman Chemical
https://www.caymanchem.com › product › disuccinimi...
Cayman Chemical
https://www.caymanchem.com › product › disuccinimi...
Disuccinimidyl glutarate (DSG) is a homobifunctional crosslinking agent that contains amine-reactive N-hydroxysuccinimide (NHS) ester groups at each end.Read more
$36.00$39 delivery
Missing: α, ω- polyethylene glycol)
4-Arm PEG-SG (SG: Succinimidyl Glutarate)
Creative PEGWorks
https://creativepegworks.com › Products
Creative PEGWorks
https://creativepegworks.com › Products
4-Arm PEG-SG is a multiarmed PEG derivative with succinimidyl NHS ester groups. PEG-SG (succinimidyl glutarate ester) is one type of PEG-NHS reagents.
Missing: α, ω-
Polyethylene Glycol (PEGs & PEOs) Supplier | High Purity
Aladdin Scientific
https://www.aladdinsci.com › ... › Biomedical Materials
Aladdin Scientific
https://www.aladdinsci.com › ... › Biomedical Materials
Aladdin Scientific specializes in producing top-tier Polyethylene Glycol (PEGs & PEOs), and more. Trusted by the global R&D industry for ...
PEG Derivative by Functional Group
SINOPEG
https://www.sinopeg.com › nhs_c111
SINOPEG
https://www.sinopeg.com › nhs_c111
α-Succinimidyl-ω-distearoyl-sn-glycero-3-phosphoethanolamino poly(ethylene glycol). Molecular Weight: 2000Da, 3500Da, 5000Da Package Size: 1g/bottle, ...Read more