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    AI Overview
    Losartan potassium (CAS 124750-99-8) is
    a potent, orally active angiotensin II receptor type 1 (AT1) antagonist, commonly used to treat hypertension, diabetic nephropathy, and to reduce cardiac hypertrophy. It functions by relaxing blood vessels and is often utilized as an analytical reference standard. 
    Key Chemical and Physical Properties (CAS 124750-99-8): 
    • Molecular Formula:
      𝐶22
      𝐻22
      𝐶𝑙𝐾𝑁6𝑂
    • Molecular Weight: 461.01 g/mol
    • Form: Solid (powder or crystals)
    • Appearance: White to off-white powder
    • Solubility: Soluble in water, alcohols, and common organic solvents.
    • Storage: Store in a cool, dark, and dry place (often recommended
      <15∘Cis less than 15 raised to the composed with power cap C
      <15∘𝐶
      ).
    • Synonyms: 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol, monopotassium salt; DuP-753; MK 954. 
    Applications: 
    • Pharmaceutical Formulation: An active pharmaceutical ingredient (API) in high blood pressure medications.
    • Analytical Standard: Used in forensics, toxicology, and pharmaceutical quality control laboratories, specifically for HPLC and UV-spectrophotometric techniques. 
    Notes on Usage: 
    • Usage: Research and development or pharmaceutical quality control; not intended for direct therapeutic use without prescription, according to SCBT.
    • Potency: Known to be a selective competitive antagonist of the AT1 receptor.
    • Stability: Products often have a limited shelf life, requiring monitoring of expiry dates Sigma-Aldrich. 
    • Losartan potassium analytical standard 124750-99-8
      Description. General description. Losartan potassium has long lasting effects, and its efficacy is generally increased, when combi...
      Sigma-Aldrich
    • Losartan Potassium | CAS 124750-99-8 | SCBT
      See product citations (10) Alternate Names: Losartan Potassium is known as a potent, synthetic AT1 receptor antagonist. Applicatio...
      Santa Cruz Biotechnology
    • Losartan potassium analytical standard 124750-99-8
      Table_title: This Item Table_content: header: | This Item | 1370462 | BP867 | row: | This Item: form powder or crystals | 1370462:
      Sigma-Aldrich
    • Losartan Potassium Pharmaceutical Secondary Standard
      Description. General description. Pharmaceutical secondary standards for application in quality control, provide pharma laboratori...
      Sigma-Aldrich
    • [Losartan Potassium (150 mg)] - CAS [124750-99-8]
      The following information is about a losartan potassium reference standard: * **Catalog number** 1370462 * **CAS RN** 124750-99-8 ...
      USP Store
    • Losartan (potassium salt) (CAS 124750-99-8)
      Product Description. Losartan is an antagonist of angiotensin II type 1b (AT1b) receptor (IC50 = 2.2 nM in COS-7 cells expressing ...
      Cayman Chemical
    • Losartan Potassium | 124750-99-8 | TCI AMERICA
      Losartan Potassium; Product No: L0232; CAS RN: 124750-99-8; Purity: >98.0%(T)(HPLC); Synonyms: 2-Butyl-4-chloro-1-[[2'-(1H-tetrazo...
      Tokyo Chemical Industry Co., Ltd.
    • Losartan potassium EP Reference Standard CAS 124750- ...
      Table_title: This Item Table_content: header: | This Item | BP867 | 61188 | row: | This Item: grade pharmaceutical primary standar...
      Sigma-Aldrich
    • Losartan (potassium salt) | CAS 124750-99-8 - Biomol
      Losartan is an antagonist of angiotensin II type 1b (AT1b) receptor (IC50 = 2.2 nM in COS-7 cells expressing the rat receptor). It...
      Biomol GmbH
    • losartan 50 mg tablet - Kaiser Permanente
      Feb 15, 2026 — Losartan is used to treat high blood pressure (hypertension) and to help protect the kidneys from damage due to diabetes. It is al...
      Kaiser Permanente
    • Losartan potassium analytical standard 124750-99-8
      Description. General description. Losartan potassium has long lasting effects, and its efficacy is generally increased, when combi...
      Sigma-Aldrich
    • Losartan Potassium | CAS 124750-99-8 | SCBT
      See product citations (10) Alternate Names: Losartan Potassium is known as a potent, synthetic AT1 receptor antagonist. Applicatio...
      Santa Cruz Biotechnology
    • Losartan potassium analytical standard 124750-99-8
      Table_title: This Item Table_content: header: | This Item | 1370462 | BP867 | row: | This Item: form powder or crystals | 1370462:
      Sigma-Aldrich
    Show all
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    Losartan potassium analytical standard 124750-99-8


    Sigma-Aldrich
    https://www.sigmaaldrich.com › product › sial
    Sigma-Aldrich
    https://www.sigmaaldrich.com › product › sial
    Losartan is an angiotensin II receptor antagonist that is used to treat hypertension. It has imidazole, tetrazole, and benzene rings as part of its structure.Read more
    LOSARTAN POTASSIUM 124750-99-8 from www.sigmaaldrich.com
    $229.00 · In stock · $23.50 delivery

    Losartan Potassium | 124750-99-8 | TCI AMERICA


    Tokyo Chemical Industry Co., Ltd.
    https://www.tcichemicals.com › ...
    Tokyo Chemical Industry Co., Ltd.
    https://www.tcichemicals.com › ...
    In clinical, its water-soluble potassium salt (DUP 753) is used for the treatment of hypertension. Recently, AT1 receptor antagonists (blockers), such as ...Read more

    [Losartan Potassium (150 mg)] - CAS [124750-99-8]


    USP Store
    https://store.usp.org › product
    USP Store
    https://store.usp.org › product
    Losartan Potassium (150 mg). Catalog No : 1370462. CAS RN®. 124750-99-8. Molecular Formula: C22H22ClN6OK. Product Type: Reference Standard. $297.00. remove add.Read more
    $297.00 · $50 delivery · 30-day returns

    Losartan (potassium salt) (CAS 124750-99-8)


    Cayman Chemical
    https://www.caymanchem.com › product › losartan-pot...
    Cayman Chemical
    https://www.caymanchem.com › product › losartan-pot...
    Losartan is an antagonist of angiotensin II type 1b (AT1b) receptor (IC50 = 2.2 nM in COS-7 cells expressing the rat receptor). It reduces U-46619-induced ...Read more
    LOSARTAN POTASSIUM 124750-99-8 from www.caymanchem.com
    $39 delivery

    Losartan Potassium (CAS 124750-99-8)


    Santa Cruz Biotechnology
    https://www.scbt.com › ... › Signal Transduction 02
    Santa Cruz Biotechnology
    https://www.scbt.com › ... › Signal Transduction 02
    Losartan Potassium is known as a potent, synthetic AT1 receptor antagonist. Application: Losartan Potassium is a specific antagonist of the AT1 receptor with ...Read more
    LOSARTAN POTASSIUM 124750-99-8 from www.scbt.com
    $35.50 delivery

    Losartan (potassium salt) | CAS 124750-99-8


    Biomol GmbH
    https://www.biomol.com › ... › Chemicals › Biochemicals
    Biomol GmbH
    https://www.biomol.com › ... › Chemicals › Biochemicals
    Losartan is an antagonist of angiotensin II type 1b (AT1b) receptor (IC50 = 2.2 nM in COS-7 cells expressing the rat receptor). It reduces U-46619-induced ...Read more
    LOSARTAN POTASSIUM 124750-99-8 from www.biomol.com

    Losartan Potassium Pharmaceutical Secondary Standard


    Sigma-Aldrich
    https://www.sigmaaldrich.com › product › sial › phr1602
    Sigma-Aldrich
    https://www.sigmaaldrich.com › product › sial › phr1602
    About This Item ; Empirical Formula (Hill Notation):. C22H22ClKN6O ; CAS Number: 124750-99-8 ; Molecular Weight: 461.00 ; UNSPSC Code: 41116107 ; NACRES: NA.24.Read more
    LOSARTAN POTASSIUM 124750-99-8 from www.sigmaaldrich.com
    $122.00 · 2–4 day delivery

    CAS Number 124750-99-8 | Losartan Potassium


    Spectrum Chemical
    https://www.spectrumchemical.com › cas › 124750-99-8
    Spectrum Chemical
    https://www.spectrumchemical.com › cas › 124750-99-8
    Purchase and Find information on CAS 124750-99-8, Losartan Potassium which meets or exceeds the grade requirements or specifications for each fine chemical.
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    Losartan potassium | 124750-99-8


    ChemicalBook
    https://www.chemicalbook.com › ... › CAS DataBase List
    ChemicalBook
    https://www.chemicalbook.com › ... › CAS DataBase List
    It functions by relaxing blood vessels so that blood can flow more easily. It is also effective to help protect the kidneys from damage caused by diabetes and ...Read more
    LOSARTAN POTASSIUM 124750-99-8 from www.chemicalbook.com

    Losartan Potassium 124750-99-8 - Sinoway


    china-sinoway.com
    https://www.china-sinoway.com › API
    china-sinoway.com
    https://www.china-sinoway.com › API
    Losartan Potassium is mainly used for treatment of high blood pressure. *Products under the patent are only for R&D use. Hot Tags : LOSARTAN POTASSIUM powder ...Read more
    LOSARTAN POTASSIUM 124750-99-8 from www.china-sinoway.com
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