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    Long Island City, NY 11101
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    AI Overview
    Hexamidine Diisethionate is an exceptionally mild, broad-spectrum antiseptic and preservative used in sensitive skin, anti-acne, and anti-dandruff products, often replacing formaldehyde-releasing agents. It is used at low concentrations (
    ≤0.1
    %
    ) to target bacteria while remaining well-tolerated on skin and mucous membranes. 
    Key Product Applications 
    • Sensitive/Irritated Skin: Gentle formulations for sensitive or irritated skin, reducing redness and discomfort.
    • Acne Care: Found in acne treatments and facial cleansers (e.g., toners, serums) to control bacteria.
    • Scalp & Hair Care: Used in shampoos and conditioners to manage dandruff, itching, and hair care products for people of color.
    • Personal Care: Used in deodorants and antiperspirants to target odor-causing bacteria. 
    Product Types Containing Hexamidine Diisethionate 
    • Cleansers & Toners: Gentle cleansers that require effective preservation without drying the skin.
    • Creams & Serums: Daily leave-on skincare targeting acne or oily skin.
    • Scalp Treatments: Shampoos and conditioners addressing scalp irritation.
    • Intimate Care: Products for sensitive mucous membranes. 
    Key Characteristics 
    • Mildness: Low irritation potential, making it safe for delicate skin areas.
    • Efficacy: Highly effective against acne and odor-causing microbes.
    • Stability: Stable in a pH range of 3.5 – 6.0. 
    It is important to note that Hexamidine Diisethionate is a cationic substance, which means it may require special formulation considerations (like avoiding anionic thickeners like Xanthan gum). 
    • From pharma to skin care products Hexamidine diisethionate ...
      Apr 16, 2026 — Abstract. The search for safe preservatives is facing several challenges today. Potent preservation systems which are yet gentle t...
      www.teknoscienze.com
    • MinaSolve Hexam
      hexamidine diisethionate. MinaSolve Hexam is a high-quality form of Hexamidine Diisethionate, an exceptionally mild preservative w...
      Minasolve
    • HEXAMIDINE DIISETHIONATE - SpecialChem
      Aug 14, 2025 — Hexamidine Diisethionate helps control the growth of bacteria, particularly acne-causing and odor-causing microbes - making it ide...
      SpecialChem
    • Products That Contain HEXAMIDINE DIISETHIONATE - EWG
      Shampoo & Conditioner * Shampoo & Conditioner. * Detangler. * Styling. * Detangler. * Hair Removal. * Depilatory. * Hair Products ...
      Environmental Working Group
    • Hexamidine diisethionate: properties and applications in skin health
      Aug 16, 2023 — Hexamidine diisethionate is considered safe for use in cosmetics and toiletries at concentrations less than or equal to 0.10%. The...
      ChemicalBook
    • Hexamidine Diisethionate - Anti-acne/Anti-dandruff/A... - Anallerg
      At the same time, Hexamidine Diisethionate is also a new anti-acne and acne-removing functional component. As an efficient broad-s...
      anallergactives.com
    • Hexamidine Diisethionate Powder - HUILIN BIO
      Table_title: Hexamidine Diisethionate Powder Table_content: header: | Microbiological test | Strain reference number | MMC/ug ML-I...
      Xi'an Huilin Bio-Tech Co., Ltd
    • Hexamidine diisethionate - CHEN LANG BIO TECH
      Nov 5, 2025 — In facial creams, gels, and serums, this compound serves dual functionality: maintaining microbiological stability and delivering ...
      CHEN LANG BIO TECH
    • Preservative solutions for Skin Care, Baby Care, Sensitive Areas
      Related to its structure, MinaSolve Hexam is a stable ingredient that does not contain, nor release formaldehyde or any other subs...
      pub-mediabox-storage.rxweb-prd.com
    • From pharma to skin care products Hexamidine diisethionate ...
      Apr 16, 2026 — Abstract. The search for safe preservatives is facing several challenges today. Potent preservation systems which are yet gentle t...
      www.teknoscienze.com
    • MinaSolve Hexam
      hexamidine diisethionate. MinaSolve Hexam is a high-quality form of Hexamidine Diisethionate, an exceptionally mild preservative w...
      Minasolve
    • HEXAMIDINE DIISETHIONATE - SpecialChem
      Aug 14, 2025 — Hexamidine Diisethionate helps control the growth of bacteria, particularly acne-causing and odor-causing microbes - making it ide...
      SpecialChem
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    Web results

    MinaSolve Hexam


    Minasolve
    https://minasolve.com › Products
    Minasolve
    https://minasolve.com › Products
    MinaSolve Hexam is a high-quality form of Hexamidine Diisethionate, an exceptionally mild preservative with a long history of safe use.Read more
    Missing: Mildness ‎| Show results with: Mildness
    People also ask
    Is hexamidine diisethionate safe?
    Safety Profile

    Hexamidine Diisethionate is safe for cosmetic use and has a low irritation potential.    Aug 14, 2025

    HEXAMIDINE DIISETHIONATE - SpecialChem


    SpecialChem
    https://www.specialchem.com › Cosmetics › INCI names
    SpecialChem
    https://www.specialchem.com › Cosmetics › INCI names
    What is hexamidine diisethionate used for?
    Hexamidine diisethionate is a commonly used antimicrobial agent for the skin, with a recommended dosage of 0.10%. It is also used as a preservative, with a dosage ranging from 0.01% to 0.1%. Bioactive HD 100, which contains Hexamidine diisethionate, is soluble in water at 80°C and in propylene glycol at 60°C.Feb 2, 2024

    Hexamidine Diisethionate: A Highly Effective, Broad-Spectrum ...


    ChemicalBook
    https://www.chemicalbook.com › article › hexamidine-di...
    ChemicalBook
    https://www.chemicalbook.com › article › hexamidine-di...
    Is Hexomedine safe?
    Open Wounds: hexamidine should not be applied to open wounds, cuts, or abrasions, as it may cause irritation and delay the healing process. Mucous Membranes: Avoid applying hexamidine to mucous membranes, such as the eyes, mouth, or genital areas, as it may cause irritation and discomfort.

    hexamidine | Dosing & Uses - medtigo


    medtigo
    https://medtigo.com › drug › hexamidine
    medtigo
    https://medtigo.com › drug › hexamidine
    Is hexamidine good for acne?
    A clinical trial demonstrated that treatment of acne patients with a topical combination of retinol, rose extract, and hexamidine diisethionate resulted in a significant amelioration in terms of acne lesions counts and acne grade [25].Dec 24, 2025

    Medicinal Plants for Acne Vulgaris: An Evidence‐Based Review of ... - PMC


    PMC - NIH
    https://pmc.ncbi.nlm.nih.gov › articles › PMC12729506
    PMC - NIH
    https://pmc.ncbi.nlm.nih.gov › articles › PMC12729506

    Web results

    Products That Contain HEXAMIDINE DIISETHIONATE


    Environmental Working Group
    https://www.ewg.org › skindeep › browse › ingredients
    Environmental Working Group
    https://www.ewg.org › skindeep › browse › ingredients
    Vivier LEXXEL Moisturizing Cream. Vivier. LEXXEL Moisturizing Cream ; Farmacy Cheer Up Brightening Vitamin C Eye Cream with Acerola Cherry. Farmacy. Cheer Up ...Read more

    HEXAMIDINE DIISETHIONATE


    SpecialChem
    https://www.specialchem.com › Cosmetics › INCI names
    SpecialChem
    https://www.specialchem.com › Cosmetics › INCI names
    Aug 14, 2025 — Hexamidine Diisethionate is a preservative, antibacterial, and anti-inflammatory agent extensively used in cosmetics and personal care ...Read more
    Missing: Mildness ‎| Show results with: Mildness
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    Duane Reade
    2.7112 Google reviews
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    Drugstore & pharmacy chain selling products including cosmetics, vitamins & mini-mart basics.
    Departments: Duane Reade Pharmacy · Duane Reade Photo · Walgreens Photo
    Address: 155 E 34th St, New York, NY 10016
    Phone: (212) 683-3042

    Hours

    Duane Reade
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    Duane Reade Pharmacy
    12 AM–1:30 PM, 2 PM–12 AM
    Saturday12 AM–1:30 PM, 2 PM–12 AM
    Sunday12 AM–1:30 PM, 2 PM–1:30 AM
    Monday2 AM–1:30 AM
    Tuesday2 AM–1:30 AM
    Wednesday2 AM–1:30 AM
    Thursday2 AM–1:30 AM
    Friday2 AM–12 AM
    Walgreens Photo
    Open 24 hours
    SaturdayOpen 24 hours
    SundayOpen 24 hours
    MondayOpen 24 hours
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    TuesdayOpen 24 hours
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    ThursdayOpen 24 hours
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    Confirmed by this business 7 days ago
    Hours:
    Open 24 hours
    Pharmacy: Open · Closes 1:30 PM Sun
    · More hours
    Confirmed by this business 7 days ago
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    WednesdayOpen 24 hours
    ThursdayOpen 24 hours
    FridayOpen 24 hours
    Confirmed by this business 7 days ago
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    • Duane Reade
      Place name
    • Convenience store
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    • 155 E 34th St, New York, NY 10016
      Place location
    • Open 24 hours
      Place opening hours
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    Order: walgreens.com, instacart.com, doordash.com
     
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      Ted Martinez
      "This place is the bomb 24 hours!"
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      From Duane Reade
      "Duane Reade is a neighborhood pharmacy and convenience retailer serving New York City with health, wellness, and everyday essentials. Many locations offer full-service pharmacy care, including prescription refills, medication counseling,...  More
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      Web results

      Hexamidine Diisethionate (with Product List)


      INCIDecoder
      https://incidecoder.com › ingredients › hexamidine-diis...
      INCIDecoder
      https://incidecoder.com › ingredients › hexamidine-diis...
      Products with Hexamidine Diisethionate. Cooper Hexomedine Duvaderm Molecular Shield Mist Olay Professional Prox Hydra Firming Anti-Aging Face Cream ...Read more
      Missing: Mildness ‎| Show results with: Mildness

      From pharma to skin care products Hexamidine diisethionate ...


      teknoscienze.com
      https://www.teknoscienze.com › Articles
      teknoscienze.com
      https://www.teknoscienze.com › Articles
      Its mildness and its efficacy at low use levels enable applications on sensitive skin, and even on mucous membranes. This article reviews the safety and ...Read more

      A double-blind randomized controlled comparison of ...


      National Institutes of Health (.gov)
      https://pubmed.ncbi.nlm.nih.gov › ...
      National Institutes of Health (.gov)
      https://pubmed.ncbi.nlm.nih.gov › ...
      by HE Lee · 2011 · Cited by 21 — In this study, we compared the efficacy and safety of the combination product APDDR-0901 (0.03% retinol, 0.7% rose extract, and 0.05% hexamidine diisethionate) ...Read more
      Missing: Mildness ‎| Show results with: Mildness

      Hexamidine Diisethionate Antimicrobial Efficacy Safety and ...


      Drop(Nanjing)Bio-Tech Co.,Ltd.
      https://www.drop-bio.com › hexamidine-diisethionate-an...
      Drop(Nanjing)Bio-Tech Co.,Ltd.
      https://www.drop-bio.com › hexamidine-diisethionate-an...
      Hexamidine Diisethionate is a compound with broad spectrum antimicrobial and antibacterial properties. If you are interested, please contact us for samples.Read more

      Hexamidine diisethionate: properties and applications in ...


      ChemicalBook
      https://www.chemicalbook.com › article › hexamidine-...
      ChemicalBook
      https://www.chemicalbook.com › article › hexamidine-...
      Aug 16, 2023 — It has antimicrobial and anti-inflammatory properties, making it suitable for skincare products. Hexamidine diisethionate exhibits good ...Read more
      Missing: Mildness ‎| Show results with: Mildness

      Hexamidine diisethionate


      CHEN LANG BIO TECH
      https://mk.chenlangbio.com › knowledge › what-is-hex...
      CHEN LANG BIO TECH
      https://mk.chenlangbio.com › knowledge › what-is-hex...
      Nov 5, 2025 — In deodorant formulations, the ingredient acts as a mild, non-sensitising antimicrobial that suppresses odor-causing bacteria without disrupting ...Read more

      Find Hexamidine Diisethionate free skin, beauty and ...


      SkinSAFE
      https://www.skinsafeproducts.com › search › products
      SkinSAFE
      https://www.skinsafeproducts.com › search › products
      Find beauty, skin and household products that are free of Hexamidine Diisethionate. SkinSAFE recommends products based on ingredients.
      Missing: Mildness ‎| Show results with: Mildness
      People also search for
      Hexamidine diisethionate mildness products safe
      Hexamidine diisethionate mildness products in cosmetics
      Hexamidine diisethionate products
      Hexamidine diisethionate eye drops
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