Skip to main contentAccessibility help
Accessibility feedback
Press / to jump to the search box
Choose what you’re giving feedback on
  • Delete
  • See more
  • Delete
    • See more
    • Report inappropriate predictions
    Quick Settings
    Sign in
    AI Mode
    All
    Shopping
    Images
    Videos
    Forums
    Short videos
    More
    Tools

    Search Results

    Any time
    Any time
    Past hour
    Past 24 hours
    Past week
    Past month
    Past year
    Custom range...
    Custom date range
    Go
    All results
    All results
    Verbatim
    Advanced Search
    About 16,700 results (0.27s) 
    Ctrl+Shift+X to select
    An AI Overview is not available for this searchCan't generate an AI overview right now. Try again later.
    AI Overview
    Methyl divatate, also known by its chemical name 2,4-dihydroxy-6-propyl-benzoic acid methyl ester (CAS No. 55382-52-0), is an organic compound used extensively as a building block and intermediate in organic synthesis. It is notably employed as a precursor for the production of cannabidiol (CBD) and cannabidivarin. 
    Key Information and Properties 
    • Alternative Names: Methyl 2,4-dihydroxy-6-propylbenzoate; Methyl Divarinolcarboxylate; Benzoic acid, 2,4-dihydroxy-6-propyl-, methyl ester.
    • Molecular Formula:
      C11
      H14
      O4
      .
    • Molecular Weight: 210.23 g/mol.
    • Appearance: White to off-white crystalline solid or powder.
    • Purity: Commonly available at 98%–99.5% purity, suitable for pharmaceutical research. 
    Applications in Organic Synthesis 
    Methyl divatate serves as a crucial intermediate, particularly in the synthesis of resorcinolic compounds and natural products. 
    • CBD Intermediates: It is widely used in the specialized manufacturing of cannabidivarin and other cannabidiol analogs.
    • Pharmaceutical and Fine Chemicals: As a bulk drug intermediate, it is used in the synthesis of other fine chemicals, potentially in agrochemical, pesticide, or herbicide development.
    • Natural Product Synthesis: It can serve as a building block for complex organic molecules requiring a 2,4-dihydroxy-6-propylbenzene structure. 
    Synthesis of Methyl Divatate 
    Methyl divatate can be synthesized by the esterification of 2,4-dihydroxy-6-propylbenzoic acid (divarinolic acid) in methanol using a catalytic amount of concentrated sulfuric acid, followed by purification via solvent removal, extraction (e.g., ethyl acetate), and silica gel column chromatography. Another route involves the synthesis from (E)-3-hepten-2-one and dimethyl malonate. 
    Safety and Handling 
    • Handling: It should be handled with care in a well-ventilated area, using suitable protective clothing and gloves.
    • Storage: Proper storage involves keeping it away from strong oxidizing agents to maintain stability. 
    • 2,4-dihydroxy-6-propyl-benzoic acid methyl ester | 55382-52-0
      Oct 22, 2024 — Table_title: 2,4-dihydroxy-6-propyl-benzoic acid methyl ester price Table_content: header: | Manufacturer | Product number | Produ...
      ChemicalBook
    • 2,4-dihydroxy-6-propyl-benzoic acid methyl ester cas 55382 ...
      Jul 6, 2023 — The propyl group (-CH2CH2CH3) is attached to one of the hydroxyl groups on the benzene ring. 2,4-dihydroxy-6-propyl-benzoic acid m...
      Shandong Minglang Chemical Co., Ltd
    • 2,4-dihydroxy-6-propyl-benzoic acid methyl ester | 55382-52-0
      Oct 22, 2024 — 2,4-dihydroxy-6-propyl-benzoic acid methyl ester Chemical Properties,Uses,Production. Description. 2,4-dihydroxy-6-propyl-benzoic ...
      ChemicalBook
    • 2,4-dihydroxy-6-propyl-benzoic acid methyl ester CAS 55382-52-0 ...
      Jan 21, 2024 — Buy 2,4-dihydroxy-6-propyl-benzoic acid methyl ester CAS 55382-52-0 Tonnage level With stock from Shandong Ranhang Biotechnology C...
      Echemi
    • D-Phenylglycine methyl ester hydrochloride（CAS# 19883-41-1
      S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 – Wear suitable protect...
      Xinchem Corporation
    • 2,4-dihydroxy-6-propyl-benzoic acid methyl ester cas 55382 ...
      Jul 6, 2023 — 2,4-dihydroxy-6-propyl-benzoic acid methyl ester cas 55382-52-0. Home >> News >> News >> 2,4-dihydroxy-6-propyl-benzoic acid methy...
      Shandong Minglang Chemical Co., Ltd
    • 2,4-dihydroxy-6-propyl-benzoic acid methyl ester 99% White powder ...
      Jul 30, 2022 — Product Description * Product Name: 2,4-dihydroxy-6-propyl-benzoic acid methyl ester. * CAS No.: 55382-52-0. * Molecular Formula: ...
      Echemi
    • 2,4-dihydroxy-6-propyl-benzoic acid methyl ester | 55382-52-0
      Oct 22, 2024 — 2,4-dihydroxy-6-propyl-benzoic acid methyl ester Chemical Properties,Uses,Production. Description. 2,4-dihydroxy-6-propyl-benzoic ...
      ChemicalBook
    • 2,4-dihydroxy-6-propyl-benzoic acid methyl ester CAS 55382-52-0 ...
      Jan 21, 2024 — Buy 2,4-dihydroxy-6-propyl-benzoic acid methyl ester CAS 55382-52-0 Tonnage level With stock from Shandong Ranhang Biotechnology C...
      Echemi
    • D-Phenylglycine methyl ester hydrochloride（CAS# 19883-41-1
      S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 – Wear suitable protect...
      Xinchem Corporation
    Show all
    Dive deeper in AI Mode
    AI can make mistakes, so double-check responses
    Share
    Facebook
    WhatsApp
    X
    Email
    Click to copy link
    Share link
    Link copied
    Thank you
    Your feedback helps Google improve. See our Privacy Policy.
    Share more feedback
    Report a problem
    Close
    Thank you
    Your feedback helps Google improve. See our Privacy Policy.
    Share more feedback
    Report a problem
    Close
    Thank you
    Your feedback helps Google improve. See our Privacy Policy.
    Share more feedback
    Report a problem
    Close
    Show more
    My Ad Center

    Web results

    A Convenient Route to Enantiomerically Pure 2-Substituted ...


    ACS Publications
    https://pubs.acs.org › doi
    ACS Publications
    https://pubs.acs.org › doi
    Chiral building blocks for the asymmetric synthesis of natural products or other biologically active compounds have been extensively investigated.Read more
    Missing: divatate ‎| Show results with: divatate

    Methylation


    Wikipedia
    https://en.wikipedia.org › wiki › Methylation
    Wikipedia
    https://en.wikipedia.org › wiki › Methylation
    Methylation, in the chemical sciences, is the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.Read more
    Missing: divatate ‎| Show results with: divatate

    Installing the “magic methyl” – C–H methylation in synthesis


    RSC Publishing
    https://pubs.rsc.org › content › articlehtml
    RSC Publishing
    https://pubs.rsc.org › content › articlehtml
    by D Aynetdinova · 2021 · Cited by 242 — This review will cover the diverse techniques that have been employed to enable the selective installation of the C–Me bond in a wide range of chemical ...Read more
    Missing: divatate ‎| Show results with: divatate

    Factory Supply Custom Synthesis Available Methyl Divatate,Custom ...


    qixiolivetol.com
    https://www.qixiolivetol.com › tag › custom-synthesis-av...
    qixiolivetol.com
    https://www.qixiolivetol.com › tag › custom-synthesis-av...
    Methyl divatate(CAS No.55382-52-0) is a synthetic organic compound belonging to the class of ​alkylresorcinol derivatives. It features a resorcinol core ...

    Method for preparing methyl dihydrojasmonate


    Google Patents
    https://patents.google.com › patent
    Google Patents
    https://patents.google.com › patent
    The invention provides a method for synthesizing methyl dihydrojasmonate, which uses 2-pentylcyclopentenone as a raw material and performs 1,4-Michael ...

    Organic Syntheses Procedure


    Organic Syntheses
    http://orgsyn.org › demo
    Organic Syntheses
    http://orgsyn.org › demo
    In this report in Organic Syntheses we describe the synthesis of MIDA boronate building blocks using MIDA anhydride 1, a reagent which expands the range and ...Read more
    Missing: Methyl ‎divatate
    People also ask
    What is the strongest methylating agent?
    Trimethyloxonium tetrafluoroborate
    Trimethyloxonium tetrafluoroborate is generally ranked as the strongest commercially available reagent for electrophilic methylation, being stronger than methyl sulfonate esters, including methyl triflate and methyl fluorosulfonate ("magic methyl").

    Trimethyloxonium tetrafluoroborate - Wikipedia


    Wikipedia
    https://en.wikipedia.org › wiki › Trimethyloxonium_tetr...
    Wikipedia
    https://en.wikipedia.org › wiki › Trimethyloxonium_tetr...
    What are the methylating agents in organic synthesis?
    Methylations are commonly performed using electrophilic methyl sources such as iodomethane, dimethyl sulfate, dimethyl carbonate, or tetramethylammonium chloride. Less common but more powerful (and more dangerous) methylating reagents include methyl triflate, diazomethane, and methyl fluorosulfonate (magic methyl).

    Methylation - Wikipedia


    Wikipedia
    https://en.wikipedia.org › wiki › Methylation
    Wikipedia
    https://en.wikipedia.org › wiki › Methylation
    How is methyl benzoate synthesized?
    Methyl benzoate (MB) compounds are prepared by reacting various benzoic acids with methanol using an acidic catalyst.May 22, 2023

    Synthesis of a Series of Methyl Benzoates through Esterification ...


    MDPI
    https://www.mdpi.com › ...
    MDPI
    https://www.mdpi.com › ...
    Is DMSO a methylating agent?
    Abstract. DMSO methylates a broad range of amines in the presence of formic acid, providing a novel, green and practical method for amine methylation.Jan 3, 2014

    A general method for N-methylation of amines and nitro compounds with ...


    PubMed
    https://pubmed.ncbi.nlm.nih.gov › ...
    PubMed
    https://pubmed.ncbi.nlm.nih.gov › ...

    Web results

    Installation of d3-methyl group to drugs by continuous-flow ...


    PubMed Central (PMC) (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC12663303
    PubMed Central (PMC) (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC12663303
    by W Ou · 2025 · Cited by 2 — The methyl group is one of the most fundamental and simplest structural units in synthetic and medicinal chemistry, playing a crucial role in ...Read more
    Missing: divatate ‎| Show results with: divatate

    Biocatalytic stereoselective synthesis of methyl mandelates ...


    ScienceDirect.com
    https://www.sciencedirect.com › science › article › pii
    ScienceDirect.com
    https://www.sciencedirect.com › science › article › pii
    by L Xie · 2024 · Cited by 12 — Chiral methyl mandelates are useful synthons in organic transformation and pharmaceutical synthesis. Green synthesis of these valuable compounds by direct C ...Read more
    Missing: divatate ‎| Show results with: divatate

    Diazomethane Mechanism, Carboxylic Acid To Methyl Ester ...


    YouTube · Organic Mechanisms
    2.2K+ views · 5 years ago
    YouTube · Organic Mechanisms
    2.2K+ views · 5 years ago
    1:00
    The mechanism for the methylation of carboxylic acids using diazomethane. Diazomethane is the simplest diazo compound and is often used in ...
    Organic Mechanisms
    YouTube·
    Feb 22, 2021

    Diazomethane Mechanism, Carboxylic Acid To Methyl Ester ...

    YouTube·Organic Mechanisms·Feb 22, 2021
    YouTube

    C-Methylation of Organic Substrates: A Comprehensive ...


    ResearchGate
    https://www.researchgate.net › publication › 34363772...
    ResearchGate
    https://www.researchgate.net › publication › 34363772...
    C-Methylation of organic substrates was achieved with a number of methyl metals, including trimethylaluminum (Me3Al), trimethylgallium (Me3Ga), ...Read more
    People also search for
    Methyl divatate for organic synthesis mechanism
    Methylation reaction Organic Chemistry
    Methylation reaction mechanism
    Methylating agent examples
    Methylation chemistry
    Methylation simple definition
    Methylation and autism
    Does methylation turn genes on or off

    Page Navigation

    12345678910Next

    Footer Links

    90012, Los Angeles, CA
     - From your IP address
     - 
    Update location
    Can't update your location
    Learn more
    Updating location...
    HelpSend feedbackPrivacyTerms
    Share
    Facebook
    WhatsApp
    X
    Email
    Click to copy link
    Share link
    Link copied
    Google apps