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    An AI Overview is not available for this searchCan't generate an AI overview right now. Try again later.
    AI Overview
    Span 85 (Sorbitan Trioleate) is a lipophilic, non-ionic surfactant and pharmaceutical-grade emulsifier (
    𝐻𝐿𝐵
    ≈1.8
     -
    2.12.1
    2.1
    ) used to stabilize water-in-oil emulsions. It is highly effective in pharmaceutical, cosmetic, and industrial applications, often paired with Span™ 85 pharma or Tween surfactants for emulsification. 
    Key Properties and Applications 
    • Composition: A mixture of partial esters of sorbitol and its mono- and dianhydrides condensed with oleic acid (roughly 85% oleic acid content).
    • Pharma/Cosmetic Function: Used for developing stable emulsions, nanoemulsions for drug delivery, and in topical formulations (creams/lotions) as a stabilizer and coupling agent.
    • Appearance: Pale-yellow viscous liquid.
    • Key Characteristics: Non-ionic, lipophilic, and biodegradable. 
    Technical Specifications 
    • CAS Number: 26266-58-0
    • HLB Value: 1.8 to 2.1
    • Solubility: Soluble in oil and organic solvents; insoluble or dispersible in water. 
    Span 85 is particularly valuable in producing specialized nano-vesicles, such as "Flexosomes," to improve drug delivery and stability. It is widely used in pharma to create high-stability oil-in-water systems when combined with Tween 80. 
    • Span™ 85 pharma
      Span 85 is a sorbitan ester with the following properties: * **Functions** Emulsifier, nonionic surfactant Span 85 is used in comb...
      Croda Pharma
    • Span™ 85 - Croda Industrial Specialties
      Span 85 is a biodegradable surfactant based on a natural fatty acid (oleic acid) and sugar alcohol sorbitol. This sorbitan ester i...
      Croda Industrial Specialties
    • Sorbitan Trioleate Span 85 | C60H108O8 | 26266-58-0 - HUANA
      At room temperature, it is in the form of a pale-yellow viscous liquid. It is a W/O emulsifier with an HLB value of 1.8.
      Guangdong Huana Chemistry Co., Ltd.
    • What Is Sorbitan Trioleate (Span) 85? - HEG
      May 20, 2025 — ... grade emulsifier with HLB ~1.8, containing approximately 85% oleic acid content. ... Pharmaceutical-grade Sorbitan Trioleate (
      hegchem.com
    • Span™ 85 | Croda Home Care
      Span 85 is a biodegradable surfactant. It's made from: * **Oleic acid** A natural fatty acid * **Sorbitol** A sugar alcohol Span 8...
      Croda Home Care
    • Span-85 - TargetMol
      Product Introduction Span-85 (Sorbitan trioleate) is a synthetic non-ionic emulsifier, which is prepared by partial esterification...
      TargetMol
    • Span™ 85 by Croda - Household, Industrial & Institutional Cleaners
      Dec 8, 2025 — Formulations. ... SP Span 85 MBAL is a biodegradable surfactant based on a natural fatty acid (oleic acid) and the sugar alcohol s...
      UL Prospector
    • Span 85 for synthesis 26266-58-0 - Sigma-Aldrich
      Application * Macromolecular Stabilization: Span® 85 is used as a stabilizer for the preparation of PMMA colloidal particles in no...
      Sigma-Aldrich
    • Sorbitan Trioleate, Span-85 | CAS 26266-58-0 - IRO Surfactant
      Packing and Storage: Packed in 200kg iron drum/plastic drum. Handle with care. Span-85 is stored in a cool, dry, and draughty plac...
      www.irosurfactant.com
    • Span™ 85 pharma
      Span 85 is a sorbitan ester with the following properties: * **Functions** Emulsifier, nonionic surfactant Span 85 is used in comb...
      Croda Pharma
    • Span™ 85 - Croda Industrial Specialties
      Span 85 is a biodegradable surfactant based on a natural fatty acid (oleic acid) and sugar alcohol sorbitol. This sorbitan ester i...
      Croda Industrial Specialties
    • Sorbitan Trioleate Span 85 | C60H108O8 | 26266-58-0 - HUANA
      At room temperature, it is in the form of a pale-yellow viscous liquid. It is a W/O emulsifier with an HLB value of 1.8.
      Guangdong Huana Chemistry Co., Ltd.
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    Span™ 85 pharma


    Croda Pharma
    https://www.crodapharma.com › Home › Product finder
    Croda Pharma
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    Span 85 is a liquid W/O emulsifier and O/W emulsion stabiliser used in nasal and metered dose inhalation dosage forms and as a dispersing agent in aerosols.Read more

    Span™ 85


    Croda Industrial Specialties
    https://www.crodaindustrialspecialties.com › product
    Croda Industrial Specialties
    https://www.crodaindustrialspecialties.com › product
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    Span 85 is a biodegradable surfactant based on a natural fatty acid (oleic acid) and sugar alcohol sorbitol. This sorbitan ester is highly effective at forming ...Read more
    Missing: Pharma ‎Grade

    Span 85 26266-58-0


    Sigma-Aldrich
    https://www.sigmaaldrich.com › Products › Biochemicals
    Sigma-Aldrich
    https://www.sigmaaldrich.com › Products › Biochemicals
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    Sorbitane trioleate, or Span 85, has been used in a study to develop a novel bottom-up process to produce nanoparticles containing protein and peptide for ...Read more
    $57.40 · In stock · $28.69 delivery
    Missing: Emulsifier ‎| Show results with: Emulsifier

    Pharma Grade Surfactant Emulsifier Span 85 - Topinchem.com


    topinchem.com
    https://www.topinchem.com › pharma-grade-surfactant-e...
    topinchem.com
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    Sorbitane trioleate, or Span 85 CAS 26266-58-0, is a non-ionic detergent. Hot Tags : Cosmetic Grade Span 85 Sorbitan Trioleate Emulsifi Lubricating Oil ...Read more

    What Is Sorbitan Trioleate (Span) 85? - HEG


    hegchem.com
    https://hegchem.com › what-is-sorbitan-monooleate-85
    hegchem.com
    https://hegchem.com › what-is-sorbitan-monooleate-85
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    May 20, 2025 — Sorbitan Trioleate (Span) 85 is a high-grade emulsifier with HLB ~1.8, containing approximately 85% oleic acid content. Its extreme ...Read more

    sorbitan trioleate, 26266-58-0


    The Good Scents Company
    https://www.thegoodscentscompany.com › data
    The Good Scents Company
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    Sorbitan Trioleate (Span 85). Odor: characteristic. Use: Sorbitan Trioleate can be used as an emulsifier and nonionic surfactant in pharmaceutical formulations.Read more

    Sorbitan Trioleate - an overview


    ScienceDirect.com
    https://www.sciencedirect.com › topics › sorbitan-trioleate
    ScienceDirect.com
    https://www.sciencedirect.com › topics › sorbitan-trioleate
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    The more lipophilic sorbitan fatty acid esters, such as sorbitan trioleate (Span 85) are alternative polar oils.Read more
    Missing: Grade ‎Emulsifier

    SPAN 20 & SPAN 85


    Bayville Chemical Supply Company Inc
    https://www.bayvillechemical.net › ...
    Bayville Chemical Supply Company Inc
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    It is used for its excellent emulsification properties in personal care, industrial cleaning, fiber finish, crop protection, water treatment, paints and ...Read more

    Sorbitan Trioleate Span 85 | C60H108O8 | 26266-58-0


    Guangdong Huana Chemistry Co., Ltd.
    https://www.huanachemical.com › Sorbitan Esters
    Guangdong Huana Chemistry Co., Ltd.
    https://www.huanachemical.com › Sorbitan Esters
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    It is a W/O emulsifier with an HLB value of 1.8. It is soluble in mineral and vegetable oil. Its functions include emulsification for cosmetics and personal ...Read more
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    Web results

    Emulsifier Span 85,Sorbitan Trioleate,CAS 26266-58-0


    hefei tNj chemical
    https://www.tnjchem.com › emulsifier-span-85-sorbitan-t...
    hefei tNj chemical
    https://www.tnjchem.com › emulsifier-span-85-sorbitan-t...
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    Mainly used in medicine, cosmetics, textiles etc. as water/oil type emulsifier, wetting agent and lubricant etc.Read more
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