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Tripterygium wilfordii (Thunder God Vine or Lei Gong Teng) is a traditional Chinese medicinal herb containing potent compounds like triptolide and celastrol, used for its significant immunosuppressive, anti-inflammatory, and anti-cancer properties. It is primarily used to treat rheumatoid arthritis, skin conditions like psoriasis, and kidney diseases. Due to high toxicity, medical supervision is essential.
Key Aspects of Tripterygium Wilfordii and Triptolide
- Active Ingredients: The peeled root contains high amounts of bioactive compounds, primarily triptolide (a diterpene triepoxide) and celastrol, which are responsible for the therapeutic effects.
- Medical Uses: It is used to treat autoimmune and inflammatory conditions, including:
- Rheumatoid Arthritis: Effective for reducing inflammation and improving disease activity, often used in Chinese medicine for refractory cases.
- Immune System Modulation:
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Thunder God Vine Root 5:1 Supplement – Tripterygium ...
Amazon.com
https://www.amazon.com › Thunder-Tripterygium-Wilf...
Amazon.com
https://www.amazon.com › Thunder-Tripterygium-Wilf...
200mg Capsules with Lei Gong Teng Extract – Thunder God Vine Extract with Triptolide – 90 CapsulesRead more
Effects of triptolide from Radix Tripterygium wilfordii ... - PMC
PubMed Central (PMC) (.gov)
https://pmc.ncbi.nlm.nih.gov › articles › PMC2709898
PubMed Central (PMC) (.gov)
https://pmc.ncbi.nlm.nih.gov › articles › PMC2709898
by C Xiao2009Cited by 47 — Triptolide is an active compound in the extract of Radix Tripterygium wilfordii (Leigongteng) [6,7]. Triptolide is immunosuppressive, cartilage protective ...Read more
Thunder God Vine - Uses, Side Effects, and More
WebMD
https://www.webmd.com › ingredientmono-824 › thun...
WebMD
https://www.webmd.com › ingredientmono-824 › thun...
Thunder god vine (Tripterygium wilfordii) is a vine that grows in southeast China. Its extracts are used in traditional and pharmaceutical Chinese medicine.Read more
Thunder God Vine Root 20:1 Supplement – Tripterygium ...
Amazon.com
https://www.amazon.com › Thunder-Tripterygium-Wilf...
Amazon.com
https://www.amazon.com › Thunder-Tripterygium-Wilf...
200mg Capsules with Lei Gong Teng Extract – Thunder God Vine Extract with Triptolide – 90 CapsulesRead more
Tripterygium Wilfordii Extract / Leigongteng Extract / Triptolide ...
china-sinoway.com
https://www.china-sinoway.com › Herbal Extract
china-sinoway.com
https://www.china-sinoway.com › Herbal Extract
Studies have shown that it has anti-oxidant, anti-rheumatoid, anti-senile dementia and anti-cancer effects. It is a diterpene lactone with multiple biological ...Read more
People also ask
What is tripterygium Wilfordii used for?
T. wilfordii is used as a herbal medicine in traditional Chinese medicine to treat joint pain, promote blood circulation, relieve rheumatism, and alleviate pain and swelling (Shen et al., 2021). In recent decades, the assessment of the therapeutic potential of T.
A comprehensive review of Tripterygium wilfordii hook. f. in the ... - Frontiers
Frontiers
https://www.frontiersin.org › fphar.2023.1282610 › full
Frontiers
https://www.frontiersin.org › fphar.2023.1282610 › full
What is another name for tripterygium Wilfordii?
thunder god vine
Tripterygium wilfordii, or léi gōng téng (Mandarin) (Chinese: 雷公藤, Japanese: raikōtō), sometimes called thunder god vine but more properly translated thunder duke vine, is a vine used in traditional Chinese medicine.
Tripterygium wilfordii - Wikipedia
Wikipedia
https://en.wikipedia.org › wiki › Tripterygium_wilfordii
Wikipedia
https://en.wikipedia.org › wiki › Tripterygium_wilfordii
How to take thunder god vine?
Thunder god vine extract has most often been used by adults in doses of 30-120 mg by mouth daily for up to 6 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Thunder God Vine - Uses, Side Effects, and More - WebMD
WebMD
https://www.webmd.com › ingredientmono-824 › thun...
WebMD
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Web results
Tripterygium wilfordii - an overview
ScienceDirect.com
https://www.sciencedirect.com › topics › tripterygium-wi...
ScienceDirect.com
https://www.sciencedirect.com › topics › tripterygium-wi...
Triptolide (25), a deterpenoid epoxide, is essential for the anti-inflammatory and immunosuppressive activities of extracts. As far as one can ascertain, based ...Read more
The Main Anticancer Bullets of the Chinese Medicinal Herb ...
PubMed Central (PMC) (.gov)
https://pmc.ncbi.nlm.nih.gov › articles › PMC6264543
PubMed Central (PMC) (.gov)
https://pmc.ncbi.nlm.nih.gov › articles › PMC6264543
by Z Liu2011Cited by 148 — The thunder god vine or Tripterygium wilfordii Hook. F. is a representative Chinese medicinal herb which has been used widely and successfully for centuries ...
Lei Gong Teng
royaltcm.com
https://www.royaltcm.com › lei_gong_teng
royaltcm.com
https://www.royaltcm.com › lei_gong_teng
Triptolide, the active ingredient purified from the plant Tripterygium wilfordii Hook F, has been shown in animal models to be effective against cancer ...Read more
Therapeutic effects and mechanisms of Tripterygium ...
Nature
https://www.nature.com › scientific reports › articles
Nature
https://www.nature.com › scientific reports › articles
by K Chen2025Cited by 5 — The results revealed that Tripterygium wilfordii extracts significantly reduced joint manifestations (arthritis index, paw swelling degree, and ...Read more
Lei Gong Teng (Radix Tripterygii Wilfordii): A Blessing or ...
Acupuncture Today
https://acupuncturetoday.com › article › 28365-lei-gong-...
Acupuncture Today
https://acupuncturetoday.com › article › 28365-lei-gong-...
According to a double-blind, placebo-controlled study, use of a lei gong teng extract for 20 weeks showed therapeutic benefit in patients with rheumatoid ...Read more