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Fast, simultaneous detection of Procalcitonin (PCT) and C-reactive protein (CRP) is achieved using portable, point-of-care (POC) lateral flow immunoassay (LFA) systems. These tests provide rapid, quantitative results in roughly 15 minutes, combining high sensitivity (for bacterial infections) with quick, on-site results.
Key Features of Combined PCT/CRP Testing
- Rapid Results: Many combo tests (e.g., Vitrosens) yield results in 15 minutes.
- Methodology: Uses lateral flow immunoassay (LFA) and fluorescence immunoassay to detect both markers from a single blood sample.
- Application: Ideal for distinguishing between bacterial and viral infections and aiding in sepsis diagnosis in ICUs.
- Components: Often involves a test cartridge, a buffer solution, and a portable, handheld reader to quantify results.
Fast Test Procedures
- Sample Collection: A small volume (e.g., 50–100 L) of whole blood, serum, or plasma is collected.
- Mixing: The sample is mixed with a buffer solution.
- Application: The mixture is added to the test cartridge.
- Reading: A portable reader/analyzer (e.g., Getein Biotech, AccuDx CQ) displays numerical results for both markers within 15–20 minutes.
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Web results
A diagnostic platform for rapid, simultaneous quantification of ...
PubMed Central (PMC) (.gov)
https://pmc.ncbi.nlm.nih.gov › articles › PMC8841998
PubMed Central (PMC) (.gov)
https://pmc.ncbi.nlm.nih.gov › articles › PMC8841998
by XE Cao2022Cited by 32 — In this study, we developed a EuNP-based duplex lateral flow strip for rapid and simultaneous detection of PCT and CRP. We first built a UV fluorescence ...Read more
PCT/CRP Fast Test Cassette
Getein Biotech Inc.
https://www.getein.com › pct-crp-fast-test-cassette_sp
Getein Biotech Inc.
https://www.getein.com › pct-crp-fast-test-cassette_sp
Getein PCT/CRP Fast Test Kit is used to identify systemic or local infection, bacterial infection or virus infection, determine the severity of infection ...Read more
CRP/PCT Combo FIA Rapid Test: Two Results, One ...
Vitrosens Biotechnology
https://vitrosens.com › one-cassette-two-answers-how-th...
Vitrosens Biotechnology
https://vitrosens.com › one-cassette-two-answers-how-th...
Apr 6, 2025 — Vitrosens' CRP/PCT combo fluorescent immunoassay delivers quantitative results for both biomarkers from a single cassette in 15 minutes ...
Clinical application of combined CRP and PCT detection in ...
Frontiers
https://www.frontiersin.org › fcimb.2025.1563170 › full
Frontiers
https://www.frontiersin.org › fcimb.2025.1563170 › full
by X Liu2025Cited by 9 — PCT, known for its high sensitivity and specificity, offers the advantages of rapid and early detection, making it a promising biomarker for ...Read more
Procalcitonin (PCT) Test & Common Biomarkers
Thermo Fisher Scientific
https://www.thermofisher.com › procalcitonin › pct-othe...
Thermo Fisher Scientific
https://www.thermofisher.com › procalcitonin › pct-othe...
PCT is the biomarker with the highest sensitivity and specificity for bacterial infection when compared to lactate, CRP, 14-15 and WBC count.Read more
PCT/CRP Fast Test Kit (Immunofluorescence Assay)
Getein Biotech Inc.
https://www.getein.com › pct-crp-fast-test-kit-immunofl...
Getein Biotech Inc.
https://www.getein.com › pct-crp-fast-test-kit-immunofl...
PCT/CRP Fast Test Kit (Immunofluorescence Assay) is intended for in vitro quantitative determination of Procalcitonin (PCT) and C-reactive protein (CRP) in ...Read more
People also ask
What is the PCT CRP fast test kit?
PCT/CRP Fast Test Kit (Immunofluorescence Assay) is intended for in vitro quantitative determination of Procalcitonin (PCT) and C-reactive protein (CRP) in human serum, plasma or whole blood samples.
PCT/CRP (25 Tests) - Cosmic Scientific Technologies
Cosmic Scientific Technologies
https://www.cosmic.net.in › product › pct-crp
Cosmic Scientific Technologies
https://www.cosmic.net.in › product › pct-crp
What will a doctor do if CRP is high?
If you have a moderately to severely elevated CRP level, it probably means you have some type of inflammation. But a CRP test can't show the cause of the inflammation or where it is in your body. Because of this, your healthcare provider will likely order additional tests if your result shows a high CRP level.May 17, 2022
C-Reactive Protein (CRP) Test: What It Is, Purpose & Results
Cleveland Clinic
https://my.clevelandclinic.org › health › diagnostics › 23...
Cleveland Clinic
https://my.clevelandclinic.org › health › diagnostics › 23...
What can falsely elevate PCT levels?
Besides infections, procalcitonin levels can be elevated in trauma, burns, certain carcinomas, cases of drug overdose (e.g., acetaminophen, amphetamine), cardiogenic shock, some autoimmune diseases (e.g., Kawasaki disease, adult-onset Still's disease), and in cirrhotic patients.
What other disease states and drugs can affect procalcitonin levels ...
InpharmD™
https://inpharmd.com › inquiries
InpharmD™
https://inpharmd.com › inquiries
Is PCT a tumor marker?
Procalcitonin (PCT) is a well-established marker for sepsis, particularly of bacterial origin. In addition, PCT serves as a promising tumor marker for medullary thyroid carcinoma.
Elevated Procalcitonin Level with Primary Hepatic Neuroendocrine ...
Journal of Radiation and Cancer Research
https://journals.lww.com › jrcr › fulltext › elevated_proc...
Journal of Radiation and Cancer Research
https://journals.lww.com › jrcr › fulltext › elevated_proc...
Web results
CRP and PCT Assays: Clinical Applications and ...
Creative Proteomics
https://cytokine.creative-proteomics.com › crp-pct-assa...
Creative Proteomics
https://cytokine.creative-proteomics.com › crp-pct-assa...
This results in the rapid synthesis and secretion of CRP into the bloodstream within hours of the initial stimulus. CRP levels peak between 36 to 50 hours post- ...Read more
A diagnostic platform for rapid, simultaneous quantification of ...
National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
Feb 8, 2022 — A fluorescence reader-based duplex LFA for simultaneous quantification of PCT and CRP was developed and successfully validated with clinical samples.Read more
Procalcitonin (PCT) testing at the point of care
Radiometer
https://www.radiometer.com › immunoassay-testing › pct...
Radiometer
https://www.radiometer.com › immunoassay-testing › pct...
The benchtop AQT90 FLEX immunoassay analyzer delivers rapid procalcitonin testing results in less than 21 minutes, aiding the early detection of sepsis.
One-step-immunoassay of procalcitonin enables rapid and ...
RSC Publishing
https://pubs.rsc.org › content › articlehtml
RSC Publishing
https://pubs.rsc.org › content › articlehtml
by JH Oh2021Cited by 5 — BRAHMS PCT-Q can rapidly detect serum PCT levels in 30 min but is only semi-quantitative and not sensitive enough to detect moderately elevated ...Read more
Scholarly articles for PCT/CRP fast detection | |
… values of PCT, hs-CRP and SAA detection in the early … - Sui - Cited by 28 Value of Combined Detection of PCT, CRP, and FIB in … - Ma - Cited by 19 … combined CRP and PCT detection in diagnosing and … - Liu - Cited by 9 | |