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    An AI Overview is not available for this searchCan't generate an AI overview right now. Try again later.
    AI Overview
    EPR spectrometers for biomedical research detect and analyze unpaired electrons in free radicals, metalloenzymes, and spin-labeled proteins, providing critical data on oxidative stress and molecular structure. Key applications include in vivo tissue oximetry, dosimetry, and membrane protein structure analysis. Modern, compact benchtop instruments, such as the Bruker EMX Nano or CIQTEK EPR100, offer high sensitivity and user-friendly automation. 
    Core Biomedical Applications 
    • Free Radical Detection: Identifying ROS/RNS to evaluate oxidative stress, cell damage, and disease mechanisms.
    • Structural Biology: Using pulse EPR (like DEER/PELDOR) to determine distances between spin labels on proteins, revealing three-dimensional, folded structures.
    • In Vivo Oximetry: Low-frequency EPR systems measure oxygen concentrations in tissues to monitor tumor environments or tissue ischemia.
    • Dosimetry: Measuring radiation-induced free radicals in tissue or tooth enamel for biological dosimetry. 
    Key EPR Spectrometer Technology 
    • Compact Benchtop Systems: Devices such as the EMX Nano or CIQTEK offer high-end performance in a smaller footprint, ideal for typical biology labs.
    • Pulse EPR (EPR100): Provides higher resolution for complex, weak dipolar interactions, vital for detailed protein studies.
    • Variable Temperature (VT): Essential for maintaining stable signals in biological samples at specialized temperatures (e.g., liquid nitrogen or helium, 10 K.
    • Next-generation Chips: New chip-scale designs (22 nm) provide 1,400 THz/s scan rates, increasing speed and potentially enhancing portability for point-of-care analysis. 
    Key Manufacturers and Systems 
    • Bruker: Leader in EPR systems, including high-end ELEXSYS (e.g., E580Q) and benchtop EMX Nano.
    • CIQTEK: Provides CW and Pulsed EPR spectrometers suitable for materials and biomedical research.
    • LINEV Systems: Offers benchtop solutions. 
    Key Research Examples 
    • Membrane Proteins: Studying protein complexes to aid in drug development.
    • Tumor Imaging: Developing 1–2 GHz in vivo imagers for mapping oxygenation and radicals in small animals. 
    • The Utility of Electron Paramagnetic Resonance ...
      Apr 15, 2026 — What are electron paramagnetic spectrometers and how are they used? EPR spectrometers are analytical tools that are primarily used...
      Spectroscopy Online
    • EPR Instruments - Electron Paramagnetic Resonance - Bruker
      Biomedical EPR applications include the detection of free radicals such as ROS and RNS to observe and evaluate oxidative stress an...
      Bruker
    • EPR Spectrometer // Physics // Marquette University
      EPR is a magnetic resonance technique that uses a magnetic field to cause unpaired electrons to absorb microwave energy. The EPR s...
      Marquette University
    Show all
    • The Utility of Electron Paramagnetic Resonance ...
      Apr 15, 2026 — What are electron paramagnetic spectrometers and how are they used? EPR spectrometers are analytical tools that are primarily used...
      Spectroscopy Online
    • EPR Instruments - Electron Paramagnetic Resonance - Bruker
      Biomedical EPR applications include the detection of free radicals such as ROS and RNS to observe and evaluate oxidative stress an...
      Bruker
    • EPR Spectrometer // Physics // Marquette University
      EPR is a magnetic resonance technique that uses a magnetic field to cause unpaired electrons to absorb microwave energy. The EPR s...
      Marquette University
    • Clinical EPR: Unique Opportunities and Some Challenges - PMC
      This paper describes the rationale and development of the first clinical EPR systems for two important clinical applications, name...
      National Institutes of Health (.gov)
    • center for biomedical epr spectroscopy and imaging - NIH RePORTER
      * We have developed prototype instrumentation enabling in vivo EPR spectroscopy and high resolution spatial or spectral-spatial im...
      National Institutes of Health (.gov)
    • Best EPR Spectrometers for Academic Labs in 2025 - CIQTEK
      Jun 4, 2025 — 2. CW EPR with Variable Temperature: A Must for Research Flexibility. For labs focusing on spin dynamics, catalytic mechanisms, or...
      CIQTEK
    • EPR100 manufacturers,X-Band Pulse EPR Spectrometer - CIQTEK
      When paired with a variable temperature system, it enables the detection of paramagnetic substances at ultralow temperatures. Puls...
      CIQTEK
    • What is Electron Paramagnetic Resonance (EPR) and What It ...
      Jan 4, 2019 — when it comes to electron paramagnetic resonance or EPR researchers have had limited choices to meet their needs for the first tim...
      3:52
      YouTube·Bruker
    • Benchtop ESR/EPR spectroscopy | Electron spine/paramagnetic resonance spectroscopy from manufacturer – LINEV Systems - X-ray Security Threat Detection Systems
      The spectrometer works by: * Measuring the absorption of microwave radiation by paramagnetic substances * Placing the sample in a ...
      LINEV Systems
    • Next-generation EPR spectrometer at reduced costs, footprint ...
      Apr 17, 2024 — An example of where EPR spectroscopy can be used is in structural biology to determine distances between radicals to determine the...
      SPECTRUM Instrumentation
    • ELEXSYS E580Q Spectrometer Installation, BioEmPiRe ...
      Apr 30, 2025 — the acceptance test regarding the high sensitivity of the new instrument was done in the most efficient way and I was impressed by...
      1m
      YouTube·Bruker
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    Web results

    EPR Instruments - Electron Paramagnetic Resonance


    Bruker
    https://www.bruker.com › products-and-solutions › epr...
    Bruker
    https://www.bruker.com › products-and-solutions › epr...
    Biomedical EPR applications include the detection of free radicals such as ROS and RNS to observe and evaluate oxidative stress and cell damage. Bruker is the ...Read more

    The Utility of Electron Paramagnetic Resonance ...


    Spectroscopy Online
    https://www.spectroscopyonline.com › view › the-utility-...
    Spectroscopy Online
    https://www.spectroscopyonline.com › view › the-utility-...
    Apr 15, 2026 — EPR spectrometers are analytical tools that are primarily used to detect reactive chemical species in fields ranging from energy storage and ...Read more

    National Biomedical EPR Center


    Medical College of Wisconsin
    https://www.mcw.edu › departments › national-biomedic...
    Medical College of Wisconsin
    https://www.mcw.edu › departments › national-biomedic...
    The EPR Center is one of the largest electron paramagnetic resonance (EPR) facilities in the nation. It was supported by an NIH P41 research resource award from ...Read more
    Missing: Spectrometer ‎| Show results with: Spectrometer

    In vivo EPR spectroscopy: biomedical and potential ...


    National Institutes of Health (.gov)
    https://pubmed.ncbi.nlm.nih.gov › ...
    National Institutes of Health (.gov)
    https://pubmed.ncbi.nlm.nih.gov › ...
    by SK Jackson · 2004 · Cited by 41 — EPR spectroscopic techniques have been developed for the measurement of oxygen and nitric oxide in vivo. Specifically, the methods for in vivo measurement ...
    Missing: Spectrometer ‎| Show results with: Spectrometer

    Benchtop EPR Spectrometer | EPR200M


    CIQTEK
    https://www.ciqtekglobal.com › benchtop-epr-spectrom...
    CIQTEK
    https://www.ciqtekglobal.com › benchtop-epr-spectrom...
    The goniometer achieves automatic and precise control from 0° to 360°, providing powerful technical support in orientation-dependent substances research, ...Read more

    Benchtop EPR spectrometer for biomedical and energy research


    Student Technology Fee
    https://techfee.uw.edu › proposal
    Student Technology Fee
    https://techfee.uw.edu › proposal
    This is used to characterize complex molecules and has broad applications in many fields of study from improving the next generation of solar cells, boosting ...Read more

    Scholarly articles for EPR Spectrometer for biomedical research

    … and powerful tool in pharmaceutical and biomedical … - ‎Carini - Cited by 30
    Biomedical applications of electron paramagnetic … - ‎Klare - Cited by 17
    … EPR spectroscopy: biomedical and potential diagnostic … - ‎Jackson - Cited by 41

    Web results

    EPR Spectrometers Products, Equipment and Reviews


    Select Science
    https://www.selectscience.net › products › techniques=e...
    Select Science
    https://www.selectscience.net › products › techniques=e...
    The Bruker Magnettech ESR5000 provides both academic and industrial laboratories with X-band research grade sensitivity plus a wide field range.Read more

    Next-generation EPR spectrometer at reduced costs, ...


    SPECTRUM Instrumentation
    https://spectrum-instrumentation.com › news › 202404_...
    SPECTRUM Instrumentation
    https://spectrum-instrumentation.com › news › 202404_...
    Apr 17, 2024 — It is used in the fields of chemistry, biology, material science, and physics to study the electronic structure of metal complexes or organic ...Read more
    Missing: biomedical ‎| Show results with: biomedical

    Optical spectrometer - EPR200-Plus - CIQTEK - EPR / for ...


    Medical EXPO
    https://www.medicalexpo.com › ... › Optical spectrometer
    Medical EXPO
    https://www.medicalexpo.com › ... › Optical spectrometer
    It can provide in-situ and non-destructive information on electron spins, orbitals, and nuclei at the microscopic scale. EPR spectrometer is particularly useful ...Read more

    Benchtop ESR/EPR spectroscopy


    LINEV Systems
    https://www.linevsystems.com › products › benchtop-sp...
    LINEV Systems
    https://www.linevsystems.com › products › benchtop-sp...
    Biochemical research: ESR spectrometers are used in biochemistry and biophysics research to study the behavior of paramagnetic centers in proteins, enzymes ...Read more
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