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    An AI Overview is not available for this searchCan't generate an AI overview right now. Try again later.
    AI Overview
    HO-PEG8-CH2CH2COOtBu (Hydroxy-PEG8-propionic acid t-butyl ester, CAS: 1334177-84-2) is a monodisperse, high-purity PEG derivative with a hydroxyl group and a t-butyl protected carboxylic acid. It is used as a hydrophilic linker in drug delivery, PROTAC synthesis, and bioorthogonal labeling, increasing water solubility. 
    Key Features & Applications: 
    • Structure: Comprises eight polyethylene glycol units (
      PEG8cap P cap E cap G sub 8
      𝑃𝐸𝐺8
      ) with a terminal
      −OHnegative OH
      −OH
       and a propionic acid t-butyl ester group.
    • Functionality: Acts as a bifunctional linker; the
      −OHnegative OH
      −OH
       can be activated (e.g., to NHS ester or mesylate) and the t-butyl ester can be deprotected to a carboxylic acid for coupling.
    • Application Areas: Crucial in PEGylation for pharmaceutical development, medical research, and surface modification.
    • Property: Enhances the water solubility of resulting compounds.
    • Storage: Generally stored at -18°C, requiring protection from light. 
    • HO-PEG8-CH2CH2COOtBu - PurePEG
      Hydroxy-PEG-Propionic acid t-butyl ester. HO-PEG8-CH2CH2COOtBu. Price. $27.00 – $411.00 Price range: $27.00 through $411.00. Full ...
      PurePEG
    • NH2-PEG8-CH2CH2COOtBu | CAS:756526-06-4 | Biopharma PEG
      NH2-PEG8-CH2CH2COOtBu is used in a variety of applications, including: * Medical research * Drug-release * Nanotechnology and new ...
      Biopharma PEG
    • H2N-PEG8-CH2CH2COOtBu [C23H47NO10] Cas:756526-06-4
      H2N-PEG8-CH2CH2COOtBu [C23H47NO10] Cas:756526-06-4 * H2N-PEG8-CH2CH2COOtBu. * Product Name:H2N-PEG8-CH2CH2COOtBu. * CAS No.:756526...
      SINOPEG
    Show all
    • HO-PEG8-CH2CH2COOtBu - PurePEG
      Hydroxy-PEG-Propionic acid t-butyl ester. HO-PEG8-CH2CH2COOtBu. Price. $27.00 – $411.00 Price range: $27.00 through $411.00. Full ...
      PurePEG
    • NH2-PEG8-CH2CH2COOtBu | CAS:756526-06-4 | Biopharma PEG
      NH2-PEG8-CH2CH2COOtBu is used in a variety of applications, including: * Medical research * Drug-release * Nanotechnology and new ...
      Biopharma PEG
    • H2N-PEG8-CH2CH2COOtBu [C23H47NO10] Cas:756526-06-4
      H2N-PEG8-CH2CH2COOtBu [C23H47NO10] Cas:756526-06-4 * H2N-PEG8-CH2CH2COOtBu. * Product Name:H2N-PEG8-CH2CH2COOtBu. * CAS No.:756526...
      SINOPEG
    • Hydroxy-PEG8-CH2-Boc (Synonyms: HO-PEG8-CH2COOtBu)
      Hydroxy-PEG8-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. For research use only. We do not s...
      MedchemExpress.com
    • HO-PEG8-CH2CH2COOH (Hydroxy-PEG8-acid) | PEG Derivative
      HO-PEG8-CH2CH2COOH (Hydroxy-PEG8-acid) is a PEG derivative containing a hydroxyl group with a terminal carboxylic acid. The termin...
      MedchemExpress.com
    • Monodispersed Poly(Ethylene Glycol) from PurePEG:HO-PEG8- ...
      Monodispersed Poly(Ethylene Glycol) from PurePEG:HO-PEG8-CH2CH2COOH. ... Poly(ethylene Glycol), abbreviated as “PEG”, is a synthet...
      MSE Supplies
    • HO-PEG8-CH2COOtBu - AxisPharm
      HO-PEG8-CH2COOtBu contains a hydroxyl group with a t-butyl protected carboxyl group. The PEG spacer increases the aqueous solubili...
      AxisPharm
    • HO-PEG8-CH2CH2COOH - PurePEG
      Hydroxy-PEG-Propionic acid. HO-PEG8-CH2CH2COOH.
      PurePEG
    • Fmoc-NH-PEG8-CH2COOH, 868594-52-9 | BroadPharm
      Fmoc-NH-PEG8-CH2COOH is a PEG linker that contains an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spa...
      BroadPharm
    • High Purity PEG Reagent, HO-PEG8-CH2CH2COOtBu, 97 ...
      High Purity PEG Reagent, HO-PEG8-CH2CH2COOtBu, 97% Min Purity, 250 mg. (No reviews yet) Write a Review ; Comments Required. Part N...
      www.calpaclab.com
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    Web results

    High Purity PEG Reagent, HO-PEG8-CH2CH2COOtBu, 97 ...


    CP Lab Safety
    https://www.calpaclab.com › high-purity-peg-reagent-ho...
    CP Lab Safety
    https://www.calpaclab.com › high-purity-peg-reagent-ho...
    High Purity PEG Reagent, HO-PEG8-CH2CH2COOtBu, 97% Min Purity, 250 mg ; Lead Time: 1-2 days ; Shipping: FREE SHIPPING on most orders over $50* ; Quantity: each ...Read more

    HO-PEG8-CH2CH2COOtBu


    PurePEG
    https://purepeg.com › product › ho-peg8-ch2ch2cootbu
    PurePEG
    https://purepeg.com › product › ho-peg8-ch2ch2cootbu
    Hydroxy-PEG-Propionic acid t-butyl ester. HO-PEG8-CH2CH2COOtBu. Price. $27.00 – $411.00 Price range: $27.00 through $411.00. Full ...Read more

    Monodispersed Poly(Ethylene Glycol) from PurePEG:HO- ...


    MSE Supplies
    https://www.msesupplies.com › products › monodisperse...
    MSE Supplies
    https://www.msesupplies.com › products › monodisperse...
    Monodispersed Poly(Ethylene Glycol) from PurePEG:HO-PEG8-CH2CH2COOtBu · Drug development: Monodisperse PEG is used to create effective drugs, especially small ...Read more

    Hydroxy-PEG8-CH2-Boc (HO-PEG8-CH2COOtBu)


    MedchemExpress.com
    https://www.medchemexpress.com › hydroxy-peg8-ch2-...
    MedchemExpress.com
    https://www.medchemexpress.com › hydroxy-peg8-ch2-...
    Hydroxy-PEG8-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. For research use only. We do not sell to patients.Read more

    Linker with Protecting Group - Monodisperse PEG


    SINOPEG
    https://www.sinopeg.com › linker-with-protecting-grou...
    SINOPEG
    https://www.sinopeg.com › linker-with-protecting-grou...
    HO-PEG12-CH2CH2COOtBu. Product Name:HO-PEG12-CH2CH2COOtBu. CAS No.:1186025-29-5. M.F.:C31H62O15. M.W:674.83. Storage:-18℃ for long term storage,avoid light.Read more

    Hydroxy-PEG8-CH2-Boc | C22H44O11 - PubChem - NIH


    National Institutes of Health (.gov)
    https://pubchem.ncbi.nlm.nih.gov › compound › Hydr...
    National Institutes of Health (.gov)
    https://pubchem.ncbi.nlm.nih.gov › compound › Hydr...
    Molecular Formula. C22H44O ; Synonyms. Hydroxy-PEG8-CH2-Boc; HO-PEG8-CH2COOtBu; 2869101-36-8; tert-Butyl 26-hydroxy-3,6,9,12,15,18,21,24-octaoxahexacosanoate ...Read more

    NH2-PEG8-CH2CH2COOtBu | CAS:756526-06-4


    Biopharma PEG
    https://www.biochempeg.com › product
    Biopharma PEG
    https://www.biochempeg.com › product
    NH2-PEG8-CH2CH2COOtBu (Amino-PEG8-t-butyl ester, CAS No. 756526-06-4) is a high-purity, monodisperse PEG linker designed for advanced bioconjugation ...Read more
    Missing: HO- ‎| Show results with: HO-

    H2N-PEG8-tBu manufacturers and suppliers in india


    ChemicalBook
    https://www.chemicalbook.com › Manufacturers-india
    ChemicalBook
    https://www.chemicalbook.com › Manufacturers-india
    Changsha Morning Shine Co., Ltd. Product Name:NH2-PEG8-CH2CH2COOtBu; Products ... HO-PEG8-CH2CH2COOH3,6,9,12-tetraoxatridecylamine Fmoc-9-Amino-4,7 ...Read more

    Hydroxyl PEG, Hydroxy linker, PEG linker


    BroadPharm
    https://broadpharm.com › product-categories › hydrox...
    BroadPharm
    https://broadpharm.com › product-categories › hydrox...
    BroadPharm provides monofunctional or heterobifunctional hydroxyl PEGs (PEG Alcohols) with various active groups, including Alkyne, carboxylic acid, ...
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    Polyethylene Glycol in Consumer Products

    You might find PEG-400 on product labels for personal care products, pharmaceuticals, and food items, or PEG-8000 on cosmetics and cleaning products. The numbers following PEG indicate the ingredient's average molecular weight — PEG-400 is a liquid, while PEG-8000 is a solid.

    A Guide to Polyethylene Glycol (PEG) - Green Seal


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    What does PEG 8 do?
    PEG-8 is a colorless liquid, soluble in water and characterized by strong hygroscopic properties. It exhibits dissolution capacity of the active ingredients. It has softening, lubricating, solubilizing, moisturizing and anti-electrostatic properties for skin care products.Mar 27, 2026

    PEG-8 (Polyethylene Glycol) - Cosmetic Ingredient INCI


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    SpecialChem
    https://www.specialchem.com › cosmetics › peg-8
    What is PEG 20000 used for?
    Base material for the use of hair-care/skin-care. Water-soluble bases which have low acute toxicity and low irritation to the skins and eyes. Moisturizing agents/moistening agents/solvents. Has binder effects and effective as the binding agent for powder cosmetic.

    Product Information｜PEG-20000｜Sanyo Chemical Industries, Ltd.


    sanyo-chemical.co.jp
    https://www.sanyo-chemical.co.jp › products
    sanyo-chemical.co.jp
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    Is polyethylene glycol toxic?
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    Web results

    HO-PEG8-CH2COOtBu


    AxisPharm
    https://axispharm.com › ... › Hydroxy-PEG-CH2CO2tBu
    AxisPharm
    https://axispharm.com › ... › Hydroxy-PEG-CH2CO2tBu
    HO-PEG8-CH2COOtBu contains a hydroxyl group with a t-butyl protected carboxyl group. The PEG spacer increases the aqueous solubility of the resulting compound.Read more
    People also search for
    Ho peg8 ch2ch2cootbu molecular structure
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