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A fourth-generation (4th gen) HIV Ag/Ab ELISA test kit is a laboratory-based immunoassay designed to detect both HIV antibodies (HIV-1/2) and the HIV-1 p24 antigen simultaneously. By detecting the p24 antigen—a structural protein of the virus that appears before antibodies—these tests significantly reduce the "diagnostic window" to as early as 14–18 days post-exposure, making them superior to older 3rd-generation antibody-only tests.
Key Features & Details
- Targeted Biomarkers: Simultaneous detection of HIV-1/2 antibodies (IgG, IgM) and HIV-1 p24 antigen.
- Window Period: Highly reliable at detecting infection as early as 4 weeks post-exposure, with many detecting infections at 18 days.
- Accuracy: Typically high sensitivity and specificity (>99%).
- Usage: Primarily used in clinical labs, blood banks, and hospitals for screening.
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Web results
Wholesale HIV Fourth Generation ELISA Test Kit ...
InTec PRODUCTS, INC.
https://www.intecasi.com › hiv-fourth-generation-elisa-te...
InTec PRODUCTS, INC.
https://www.intecasi.com › hiv-fourth-generation-elisa-te...
ELISA Diagnostic Kit for Antigen/Antibody to Human Immunodeficiency Virus. Sensitivity >99.9%. Specificity >99.9%. ISO 13485.Read more
Accu-Tell ® HIV 1+2 Ag/Ab ELISA KIT (4th generation)
AccuBioTech Co., Ltd.
https://www.accubiotech.com › ... › HIV Elisa Test
AccuBioTech Co., Ltd.
https://www.accubiotech.com › ... › HIV Elisa Test
Accu-Tell® HIV 1+2 Ag/Ab ELISA KIT is an enzyme-linked immunosorbent assay (ELISA) intended for qualitative detection of antigens and/or antibodies to Human ...Read more
HIV ELISA Kits
Biocompare
https://www.biocompare.com › pfu › soids › ELISA_Kit
Biocompare
https://www.biocompare.com › pfu › soids › ELISA_Kit
HIV ELISA kits are assays designed to measure levels of HIV-associated antigens in biological samples, such as plasma, serum, culture extracts, ...Read more
PAREEKSHAK ® HIV - Bhat Biotech
Bhat Biotech
http://www.bhatbiotech.com › elisa-hiv
Bhat Biotech
http://www.bhatbiotech.com › elisa-hiv
Ag & Ab COMBO ELISA TEST KIT is an In vitro Antigen and Antibody sandwich ELISA where in the HIV antigen p24 and Isotypes of HIV antibodies are detected ...Read more
HIV Ag/Ab Combo ELISA 4.0 (CE)
MP Biomedicals
https://www.mpbio.com › 0723040-hiv-ag-ab-combo-eli...
MP Biomedicals
https://www.mpbio.com › 0723040-hiv-ag-ab-combo-eli...
The MP Diagnostics HEV ELISA 4.0 is an enzyme-linked immunosorbent assay intended for the detection of total antibodies to Hepatitis E Virus in human serum ...
11-day delivery30-day returns
HIV Ag-Ab ELISA Kit (4th Gen)
Athenese-Dx
https://athenesedx.com › Shop
Athenese-Dx
https://athenesedx.com › Shop
The TRUSTwell HIV Ag-Ab ELISA Kit is a solid phase enzyme-linked immunoabsorbent assay for the qualitative detection of HIV-1 P24 antigen, anti-HIV-1 ...Read more
Fourth-Generation Enzyme-Linked Immunosorbent Assay for ...
PubMed Central (PMC) (.gov)
https://pmc.ncbi.nlm.nih.gov › articles › PMC88179
PubMed Central (PMC) (.gov)
https://pmc.ncbi.nlm.nih.gov › articles › PMC88179
by RD Saville2001Cited by 139 — The VIDAS HIV DUO Ultra demonstrated 100% sensitivity and 99.5% specificity overall, with a 99.7% specificity in low-risk individuals.Read more
HIV-1/2 Ab/Ag ELISA Kit
Antibodies-online.com
https://www.antibodies-online.com › kit › HIV-1+2+Ab...
Antibodies-online.com
https://www.antibodies-online.com › kit › HIV-1+2+Ab...
Sample Type. Serum ; Purpose. The HIV 1, 2 Ab/Ag ELISA Test is an ELISA kit that distinguishes itself as a fourth generation ELISA for HIV detection.Read more
People also ask
What does a 4th generation ELISA detect?
Human Immunodeficiency Virus Antigen
Fourth-Generation Enzyme-Linked Immunosorbent Assay for the Simultaneous Detection of Human Immunodeficiency Virus Antigen and Antibody.
Fourth-Generation Enzyme-Linked Immunosorbent Assay for ...
PubMed Central (PMC) (.gov)
https://pmc.ncbi.nlm.nih.gov › articles › PMC88179
PubMed Central (PMC) (.gov)
https://pmc.ncbi.nlm.nih.gov › articles › PMC88179
Is the 4th gen HIV test kit accurate?
Fourth-generation laboratory tests are extremely accurate. The key measures of accuracy are sensitivity (the percentage of results that are correctly positive when HIV is actually present) and specificity (the percentage of results that are correctly negative when HIV is not present).Feb 4, 2025
How accurate are fourth-generation combination tests for HIV ...
Aidsmap
https://www.aidsmap.com › about-hiv › how-accurate-a...
Aidsmap
https://www.aidsmap.com › about-hiv › how-accurate-a...
What is the HIV Ag AB ELISA test?
Ag & Ab COMBO ELISA TEST is an immunoassay which employs r-proteins of HIV-1 gp41, C-terminus of gp120, HIV-2 recombinant protein of gp36 along with Monoclonal Anti p24 antibodies to HIV-1 for the detection of antigen & antibodies to HIV 1&2 in human serum.
PAREEKSHAK ® HIV- 4th GEN. Ag & Ab COMBO ELISA TEST ...
Bhat Biotech
http://www.bhatbiotech.com › elisa-hiv
Bhat Biotech
http://www.bhatbiotech.com › elisa-hiv
What does a patient's results show a positive 4th generation immunoassay screen mean?
The 4th-generation assay detects antibodies to HIV-1 and HIV-2, as well as the p24 antigen, enabling earlier identification of infection following exposure. The p24 antigen may be detected as early as 14 days postexposure.Dec 1, 2025
HIV Testing - StatPearls - NCBI Bookshelf - NIH
NCBI - NIH
https://www.ncbi.nlm.nih.gov › books › NBK482145
NCBI - NIH
https://www.ncbi.nlm.nih.gov › books › NBK482145
Web results
How accurate are fourth-generation combination tests for ...
Aidsmap
https://www.aidsmap.com › about-hiv › how-accurate-a...
Aidsmap
https://www.aidsmap.com › about-hiv › how-accurate-a...
Feb 4, 2025 — They test for p24 antigen as well as antibodies, so are better suited for detecting recent infection. Their sensitivities and specificities are ...Read more
HIV ELISA 4th Gen – 96 Tests | HIV-1 p24 & Antibody Kit
Vanguard e-Mart
https://emart.vanguarddiagnostics.com › products › hiv-e...
Vanguard e-Mart
https://emart.vanguarddiagnostics.com › products › hiv-e...
The HIV ELISA 4th Generation Kit is an advanced enzyme-linked immunosorbent assay designed for the qualitative detection of HIV-1 p24 antigen and antibodies.Read more
