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    An AI Overview is not available for this searchCan't generate an AI overview right now. Try again later.
    AI Overview
    WS-3 and WS-23 are synthetic, non-menthol, food-grade cooling agents used in artificial flavors to create a cold, refreshing sensation without the strong herbal taste of menthol. They are widely used in confectionery, beverages, vaping products (e-liquids), tobacco, and oral care products. 
    Key Differences: 
    • WS-3 (N-Ethyl-2-(isopropyl)-5-methylcyclohexanecarboxamide): Provides a sharp, immediate, and long-lasting cooling effect, primarily at the back of the mouth/throat, with a slight, clean minty scent.
    • WS-23 (2-Isopropyl-N,2,3-trimethylbutyramide): Known for a "round" or "fast" cooling effect with almost zero odor or taste, often preferred for a pure icy sensation rather than a minty one. 
    Characteristics of Cooling Agents: 
    • Usage: They are frequently used in "ice-hybrid" products (e.g., fruit flavors with "ice" or "koolada" labeling).
    • Heat Resistance: Both agents, particularly WS-23, are heat-stable up to 200°C, making them suitable for baked goods and high-heat production processes.
    • Form: Usually supplied as white crystals or powder, often pre-diluted in propylene glycol (PG) for easy mixing in liquid applications.
    • Appearance in Products: Used in chewing gum, candies, beverages, toothpaste, and recently, significantly increased in popular disposable e-cigarettes like Puffbar. 
    Safety and Regulation: 
    • WS-3 and WS-23 are regulated by the FDA as food additives.
    • However, their safety when inhaled in e-liquids is not established, with some studies indicating they are used at levels higher than suggested guidelines in certain products. 
    • Cooling Agent - Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
      WS-23 is generally added at the end of the gum manufacturing process either in the coating or in the gum base, and is natural and ...
      Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
    • Ice flavours and non-menthol synthetic cooling agents in e-cigarette ...
      E-cigarettes with cooling flavours have diversified in ways that complicate tobacco control with the emergence of: (1) Ice-hybrid ...
      ResearchGate
    • Cooling Agent WS-23 - FFC / Alfa Chemistry
      Jul 1, 2024 — WS-23 is a synthetic food grade cooling agent known for its intense cooling sensation. It provides a similar cooling effect to men...
      Alfa Chemistry
    • Potentially dangerous synthetic cooling agents are used at high ...
      May 15, 2022 — Synthetic cooling agents were found not only in mint- or menthol-flavored products, but in fruit- and candy-flavored products, inc...
      EurekAlert!
    • WS-23, WS-5, WS-12, WS-3 vs Menthol for Food & Beverage
      Aug 6, 2025 — 🛒 Where to Buy WS-23 Cooling Agents in Australia? For high-quality, small-batch-friendly flavour concentrates and cooling agents,
      TasteNest
    • Cooling Agent WS-3 and WS23 | ECSA Chemicals
      Nov 21, 2023 — It is also used as a cooling agent in food industry in mint formulas, confectionery and oral care products. WS-3 provides a strong...
      ECSA Group
    • Cooling Agent - Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
      WS-23 is generally added at the end of the gum manufacturing process either in the coating or in the gum base, and is natural and ...
      Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
    • Ice flavours and non-menthol synthetic cooling agents in e-cigarette ...
      E-cigarettes with cooling flavours have diversified in ways that complicate tobacco control with the emergence of: (1) Ice-hybrid ...
      ResearchGate
    • Cooling Agent WS-23 - FFC / Alfa Chemistry
      Jul 1, 2024 — WS-23 is a synthetic food grade cooling agent known for its intense cooling sensation. It provides a similar cooling effect to men...
      Alfa Chemistry
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    Web results

    Cooling Agent WS-3 and WS23 | ECSA Chemicals


    ECSA Group
    https://blog-chemicals.ecsa.ch › ecsa-chemicals › cooling...
    ECSA Group
    https://blog-chemicals.ecsa.ch › ecsa-chemicals › cooling...
    Nov 21, 2023 — WS-23 has a stronger and longer-lasting colling effect than WS-3. WS-3 has a cool taste with minty flavor whereas WS-23 has a cooling effect ...Read more
    Missing: artificial ‎| Show results with: artificial
    People also ask
    Is WS-23 safe?
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    Explain what WS-23 is
    List other synthetic cooling agents
    Tell me about menthol in e-cigarettes
    What is WS-23 made of?
    WS-23 (methyl diisopropyl propionamide, 2-isopropyl-N,2,3-trimethylbutanamide) is a chemical compound which acts as an activator (opener) of the so-called "menthol receptor", the TRPM8 calcium channel, though with relatively low affinity and it may also act at other targets.

    WS-23 - Wikipedia


    Wikipedia
    https://en.wikipedia.org › wiki
    Wikipedia
    https://en.wikipedia.org › wiki
    What is the difference between menthol and ws23?
    Cooling effect: WS-23 is known for its clean, immediate cooling impact and has been found to cool primarily at the roof of the mouth, the back of the mouth, and the back of the tongue1. Menthol, on the other hand, offers a cooling sensation accompanied by a distinct almost minty flavor.Nov 27, 2023

    The difference between ws-23 and menthol - Titanos Group


    Titanos Group
    http://www.titanos.com › news › Market
    Titanos Group
    http://www.titanos.com › news › Market
    What is WS 3?
    Tungsten trisulfide is an inorganic compound of tungsten and sulfur with the chemical formula WS3. The compound looks like chocolate-brown powder. Tungsten trisulfide.

    Tungsten trisulfide - Wikipedia


    Wikipedia
    https://en.wikipedia.org › wiki › Tungsten_trisulfide
    Wikipedia
    https://en.wikipedia.org › wiki › Tungsten_trisulfide

    Web results

    The role of synthetic coolants, WS-3 and WS-23, in modulating ...


    PubMed Central (PMC) (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC9742959
    PubMed Central (PMC) (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC9742959
    by S Yogeswaran · 2022 · Cited by 20 — Synthetic cooling agents (WS-23 and WS-3) provide a cooling sensation. Coolants in e-cigarettes modify acellular and ROS levels in lung epithelial cells.Read more

    Cooling Agent Ws-23 Powder


    Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
    https://www.cnherbflavor.com › cooling-agent_c1
    Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
    https://www.cnherbflavor.com › cooling-agent_c1
    Cooling agent powder WS-23 is for artificial flavouring agents and synthetic flavouring ingredients which can be long-lasting cooling effect for chewing gum.Read more

    WS-23 vs WS-12 vs WS-3: The Ultimate Cooling Agent ...


    Xi'an Taima Biological Engineering Co. Ltd
    https://taimacn.com › new › ws23-vs-ws12-vs-ws3-cooli...
    Xi'an Taima Biological Engineering Co. Ltd
    https://taimacn.com › new › ws23-vs-ws12-vs-ws3-cooli...
    5 days ago — WS-23 (N,2,3-Trimethyl-2-isopropylbutanamide) is arguably the most popular cooling agent in the world today, especially in the e-liquid and ...Read more
    Missing: artificial ‎| Show results with: artificial

    WS-23, WS-5, WS-12, WS-3 vs Menthol for Food & Beverage


    TasteNest
    https://www.tastenest.com.au › post › cooling-agents-ws...
    TasteNest
    https://www.tastenest.com.au › post › cooling-agents-ws...
    Aug 6, 2025 — It brings a strong minty flavour, which makes it unsuitable when flavour clarity or neutrality is important—such as in fruity desserts, tropical ...Read more
    Missing: artificial ‎| Show results with: artificial

    Cooling agent WS-23-Anhui Chinaherb New Material


    cnherbnm.com
    https://www.cnherbnm.com › product › cooling-agent-...
    cnherbnm.com
    https://www.cnherbnm.com › product › cooling-agent-...
    Artificial Flavor Ingredients WS-3 is one of the most widely used cooling agents and is derived from menthol, although it ...Read more

    What Ingredients Are In WS 23 Cooling Agent? - Rebecca


    sxrebecca.com
    https://www.sxrebecca.com › knowledge › what-ingredi...
    sxrebecca.com
    https://www.sxrebecca.com › knowledge › what-ingredi...
    The primary constituent of WS 23 cooling agent is N,2,3-trimethyl-2-isopropylbutanamide, a synthetic compound. This sophisticated molecule consists of carbon, ...Read more

    WS-3 N-ethyl 2-isopropyl-5-methylcyclohexanecarboxamide


    The Good Scents Company
    https://www.thegoodscentscompany.com › data
    The Good Scents Company
    https://www.thegoodscentscompany.com › data
    Functional use(s) - flavoring agents. Has a minty type odor and an cooling type flavor.

    Comparison of WS-3 and WS-23 Cooling Agent Ingredients


    Mokiner
    https://mokiner.com › Product News
    Mokiner
    https://mokiner.com › Product News
    Mar 26, 2025 — Regarding the Comparison of WS-3 and WS-23 Cooling Agent Ingredients, this article will help you analyze which product you need to use.

    What is the difference between WS-3 and WS-23?


    greenspringshop.com
    https://www.greenspringshop.com › Knowledges
    greenspringshop.com
    https://www.greenspringshop.com › Knowledges
    Apr 18, 2024 — WS-23 and WS-3 are both cooling agents used in food and beverages to provide a cooling sensation without altering the flavor of the product. · WS ...Read more
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