Patients who demonstrate a response, may receive maintenance therapy for up to 24 months, consisting of subcutaneous (SC) HHT twice daily for 7 days every 28 ...

Homoharringtonine is an ester derivative of the alkaloid cephalotaxine , known for its anticancer activity as an inhibitor of protein synthesis.

Apr 22, 2005 — A novel pre-purification method was developed for producing homoharringtonine from Cephalotaxus koreana , giving high purity and yield.

Product Name, Homoharringtonine. CAS No, 26833-87-4. EC-No. Min. Order, 20mg. Purity, 98% HPLC . Supply Ability, 100kg. Release date, 2025/06/19 ...

With ≥98% purity verified by HPLC analysis, this compound effectively inhibits eukaryotic protein synthesis by binding to 80S ribosomes and blocking cell cycle ...

by W Cao · 2015 · Cited by 132 — HHT inhibited cells growth, cell viability and colony formation , as well as induced cell apoptosis through mitochondria pathway.

HHT was shown to have anti-proliferative activity on murine leukemic cells [86] with the highest activity in vitro on leukemic cell lines. Following several ...

Homoharringtonine is a natural alkaloid with significant pharmacological potential that has demonstrated promising efficacy in the treatment of hematological ...

May 16, 2024 — Natural product identified in Casearia graveolens and found in the collections: ZINC NP, DrugBankNP, AnalytiCon Discovery NPs, GNPS (Global ...