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Methoxypoly(ethylene glycol) succinimidyl butanoate (mPEG-SBA) is an amine-reactive PEGylation reagent used to modify proteins, peptides, and nanomaterials, particularly by reacting with lysine amino groups at pH 7–8. It offers a stable, non-degradable linker between the PEG chain and the succinimidyl ester. It is commonly used for PEGylation of therapeutic proteins, including EPO.
Key Characteristics and Applications
- Reactivity: mPEG-SBA reacts with amine groups, notably on lysine residues, to form stable amide bonds.
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Web results
mPEG-Succinimidyl butanoate
BOC Sciences
https://peg.bocsci.com › products › mpeg-succinimidyl-...
BOC Sciences
https://peg.bocsci.com › products › mpeg-succinimidyl-...
Methoxy polyethylene glycol-Succinimidyl butanoate (mPEG-SBA) is a modifier with one end of the methoxy group and the other end of the succinimidyl butanoate ...Read more
MPEG-680 SUCCINIMIDYLBUTANOATE
National Institutes of Health (.gov)
https://gsrs.ncats.nih.gov › ginas › app › substances
National Institutes of Health (.gov)
https://gsrs.ncats.nih.gov › ginas › app › substances
MPEG-680 SUCCINIMIDYLBUTANOATE · HYDROXYSUCCINIMIDYL ESTER OF METHOXYPOLY(ETHYLENE GLYCOL)-BUTANOIC ACID, MW 30000 · METHOXY PEG SBA (20000 MW) ; Common Name ...Read more
Analytical chromatography approaches during the ...
ScienceDirect.com
https://www.sciencedirect.com › article › abs › pii
ScienceDirect.com
https://www.sciencedirect.com › article › abs › pii
by S Kheiri2023 — Conjugation of epoetin beta (EPO) with methoxypolyethylene glycol-succinimidyl butanoate (mPEG-SBA) was studied. The compound mPEG-SBA was ...Read more
Methoxy PEG Succinimidyl Butanoate
JenKem Technology USA
https://jenkemusa.com › product › methoxy-peg-succin...
JenKem Technology USA
https://jenkemusa.com › product › methoxy-peg-succin...
JenKem Technology's Methoxy PEG Succinimidyl Butanoate (Methoxy PEG SBA) is a high quality amine reactive PEG. Longer hydrolysis half-life than SCM PEG.
$140.00
Analytical chromatography approaches during the ...
National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
by S Kheiri2023 — Conjugation of epoetin beta (EPO) with methoxypolyethylene glycol-succinimidyl butanoate (mPEG-SBA) was studied. The compound mPEG-SBA was ...
Missing: Methoxypoly( ethylene
Polyethylene Glycol Peg
SINOPEG
https://www.sinopeg.com › blog › polyethylene-glycol-...
SINOPEG
https://www.sinopeg.com › blog › polyethylene-glycol-...
Feb 21, 2025 — mPEG-SG, or methoxypolyethylene glycol succinimide glutarate, is an important polymer compound whose ester bond in its structure connects ...Read more
JENKEM TECHNOLOGY USA
ナミキ商事株式会社
https://www.namiki-s.co.jp › upload › news
ナミキ商事株式会社
https://www.namiki-s.co.jp › upload › news
PDF
JenKem Technology provides high quality activated polyethylene glycol derivatives (PEGs) for Thiol. PEGylation with high purity and low polydispersity. Methoxy ...Read more
74 pages
Methoxypolyethylene glycol 5000 propionic acid N- ...
Sigma-Aldrich
https://www.sigmaaldrich.com › product › sial
Sigma-Aldrich
https://www.sigmaaldrich.com › product › sial
Methoxypolyethylene glycol 5,000 propionic acid N-succinimidyl ester ; Quality Level. 100 ; assay. ≥80% ; form. solid ; storage temp. 2-8°C ; Storage Class. 11 - ...Read more
$1,310.00$23.50 delivery
Missing: ethylene butanoate
JENKEM TECHNOLOGY USA
JenKem Technology USA
https://www.jenkemusa.com › uploads › 2019/07
JenKem Technology USA
https://www.jenkemusa.com › uploads › 2019/07
PDF
JenKem Technology provides high quality activated polyethylene glycol derivatives (PEGs) for Thiol. PEGylation with high purity and low polydispersity. Methoxy ...Read more
73 pages
Chemical structures of methoxy polyethylene glycol ...
ResearchGate
https://www.researchgate.net › figure › Chemical-struct...
ResearchGate
https://www.researchgate.net › figure › Chemical-struct...
Chemical structures of methoxy polyethylene glycol succinimidyl agents and amylin. a The amino acids-containing amine groups are in bold .Read more
Scholarly articles for Methoxypoly(ethylene glycol) succinimidyl butanoate | |
Graft copolymers with poly (ethylene oxide) segments - Neugebauer - Cited by 162 … , and conformation of methoxypoly (ethylene glycol)‐ … - Bovara - Cited by 39 … high-density poly (ethylene glycol) as substrates for … - Schlapak - Cited by 153 | |