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AI Overview
Chymosin (or rennin) is
a key enzyme used as a food additive/processing aid to curdle milk for cheese production
. It specifically hydrolyzes
Key details about Chymosin as a food additive:
- Primary Function: Coagulates casein for cheesemaking and fermented dairy products.
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Web results
Chymosin
Wikipedia
https://en.wikipedia.org
› wiki › Chymosin
Wikipedia
https://en.wikipedia.org
› wiki › Chymosin
Dive Deeper
It
is widely used in the production of cheese
. Chymosin. Crystal structure of bovine chymosin complex with the inhibitor CP-113972.
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WHO | JECFA
World Health Organization (WHO)
https://apps.who.int
› chemical
World Health Organization (WHO)
https://apps.who.int
› chemical
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CHYMOSIN B from KLUYVEROMYCES LACTIS containing calf PROCHYMOSIN B gene
; CAS number. 9001-98-3 ; Functional Class. Food Additives ENZYME_PREPARATION ; Meeting: 37.
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Safety evaluation of the food enzyme chymosin from ... - PMC
National Institutes of Health (.gov)
https://pmc.ncbi.nlm.nih.gov
› articles › PMC9358543
National Institutes of Health (.gov)
https://pmc.ncbi.nlm.nih.gov
› articles › PMC9358543
Dive Deeper
by C Lambré
2022
Cited by 3
—
It is intended to be used in
milk processing for cheese production
and for production of fermented milk products. Dietary exposure was estimated to be up to ...
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21 CFR 184.1685 -- Rennet (animal-derived) and ...
eCFR (.gov)
https://www.ecfr.gov
› title-21 › subpart-B › section-184
eCFR (.gov)
https://www.ecfr.gov
› title-21 › subpart-B › section-184
Dive Deeper
(2)
Chymosin preparation is a clear solution containing the active enzyme chymosin
(E.C. 3.4.23.4). It is derived, via fermentation, from a nonpathogenic and ...
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Chymosin - an overview
ScienceDirect.com
https://www.sciencedirect.com
› topics › chymosin
ScienceDirect.com
https://www.sciencedirect.com
› topics › chymosin
Dive Deeper
Chymosin
was the first registered
food
enzyme produced commercially using recombinant DNA technology. It plays an important role in texture and flavor formation ...
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Final Rules: Food Additives and Color Additives
U.S. Food and Drug Administration (.gov)
https://hfpappexternal.fda.gov
› scripts › fdcc
U.S. Food and Drug Administration (.gov)
https://hfpappexternal.fda.gov
› scripts › fdcc
Dive Deeper
Direct Food Substances Affirmed as Generally Recognized as Safe; Chymosin Enzyme Preparation Derived From Escherichia Coli K-12.
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Chymosin Rennet - What is it? - New England Cheesemaking ...
New England Cheesemaking Supply Company | Cheese Making
https://help.cheesemaking.com
› article › 346-chymosi...
New England Cheesemaking Supply Company | Cheese Making
https://help.cheesemaking.com
› article › 346-chymosi...
Dive Deeper
Mar 26, 2025
—
Rennet is a complex set of enzymes, with the
chymosin
enzyme being its key component. These enzymes coagulate milk, separating it into solid ...
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Safety evaluation of the food enzyme chymosin from ... - EFSA
EFSA - Wiley Online Library
https://efsa.onlinelibrary.wiley.com
› j.efsa.2025.9665
EFSA - Wiley Online Library
https://efsa.onlinelibrary.wiley.com
› j.efsa.2025.9665
Dive Deeper
Oct 15, 2025
—
The food enzyme chymosin (EC 3.4.23.4)
is produced with the genetically modified Trichoderma reesei strain DP-Nyj88
by Genencor ...
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What people are saying
Did you know... A genetically engineered enzyme developed by Pfizer is in 90% of American cheeses. Unlabeled. The ingredient, known as fermentation-produced chymosin (FPC), is a genetically engineered version of rennet, an enzyme used to coagulate m
440+ reactions
·
3 weeks ago
GMOFreeUSA · Facebook
Advocating for clean food & environment
Americans ditch cheese after learning about Pfizer-linked ingredient | Stacy Liberatore, Daily Mail
Pfizer developed a lab-made ingredient that is now found in roughly 90 percent of American cheese, and it does not have to be labeled.
Many Americans were surprised to learn that roughly 90 percent of cheese contains a lab-made enzyme developed by Pfizer, and it does not have to be labeled.
The ingredient, known as fermentation-produced chymosin (FPC), is a genetically engineered version of rennet, an enzyme used to coagulate milk during cheesemaking.
While FPC has been used for decades, a viral social media post this week brought renewed attention to its origins, sparking widespread backlash and calls for greater transparency.
On X, one user asked, 'How is this allowed?' and others vowed to stop buying American-made cheese, saying: '[A] boycott is the only way.'
Another user shared: 'Unfortunately, I won't be buying American cheese anymore without reading the labels very car
Jan 8, 2026
OwenGregorian
X
In the United States, approximately 90% of hard cheese is made using a bioengineered ingredient known as Fermentation-Produced Chymosin (FPC). What is this ingredient? Historically, cheesemakers used animal rennet—a complex set of enzymes found in
140+ reactions
·
Jan 11, 2026
mech.eng.world
Facebook
Web results
Chymosin - Compliant food - grade enzyme preparation
GNF Chemical
https://www.gnfchem.com
› chymosin-compliant-food-g...
GNF Chemical
https://www.gnfchem.com
› chymosin-compliant-food-g...
Dive Deeper
Food additives Chymosin
· Chymosin is a key raw material for cheese production · GNF Chymosin · Chymosin, a coagulant for dairy product processing · High-quality ...
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