by EM Loi · 2020 · Cited by 10 — In this study, we resynthesized the most potent OGT inhibitor of the library, OSMI-4, and we used it to investigate OGT inhibition in different human cell ...

by TD Newton · 2019 · Cited by 32 — This work provides an early example of an H 2 Se donor that functions through a well-defined and characterized mechanism.

Protein hydrolysates are a complex mixture of free amino acids, smaller proteins and bioactive peptides that are synthesized when larger proteins are subjected ...

by TD Newton · 2021 · Cited by 34 — Hydrogen selenide (H2Se ) is a central metabolite in the biological processing of selenium for incorporation into selenoproteins, ...

by TD Newton · 2019 · Cited by 32 — Hydrolysis-based H2Se donors provide new chemical tools for investigating biological H2Se.

by AMM Rangaswamy · 2024 · Cited by 2 — We have designed structurally-optimized small molecule chromogenic esters that serve as substrate analogues for monitoring NylC acyltransferase activity in a ...

by Y Fang · 2024 — Theranostic fluorescent platforms are capable of selective delivery of small molecules to target cells with simultaneous optical monitoring.

by EM Loi · 2020 · Cited by 10 — Intracellular Hydrolysis of Small - Molecule O-Linked N-Acetylglucosamine Transferase Inhibitors Differs among Cells and Is Not Required for Its Inhibition.

DropCare® Pearl H ( hydrolyzed pearl) is a small molecule obtained by hydrolysis of shell hard proteins, which has a strong inhibitory effect on tyrosinase.

by TD Newton · 2021 · Cited by 34 — Hydrogen selenide (H2Se ) is a central metabolite in the biological processing of selenium for incorporation into selenoproteins, ...