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-Carboxyl-
-isocyanato poly(ethylene glycol) (
) is a linear heterobifunctional PEG derivative featuring a carboxylic acid group at one end and a highly reactive isocyanate group at the other. Used in PEGylation and surface modification, it enables selective conjugation with amine-containing molecules (e.g., proteins, surfaces).
Key Aspects:
- Structure:
- Reactivity: The isocyanate () group reacts readily with amino (), hydroxyl (), and thiol () groups to form stable bonds.
- Molecular Weights: Common available molecular weights include 2kDa, 3.5kDa, 5kDa, 10kDa, and 20kDa.
- Applications: Used in pharmacology, drug delivery, and chemical synthesis for bridging or functionalizing molecules.
- Availability: Offered in functionalized formulations (often as a solid or viscous liquid) by specialty chemical suppliers like CD Bioparticles and Amerigo Scientific.
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Web results
α-Carboxyl-ω-isocyanato poly(ethylene glycol) [HOOC ...
Amerigo Scientific
https://www.amerigoscientific.com › carboxyl-isocyanat...
Amerigo Scientific
https://www.amerigoscientific.com › carboxyl-isocyanat...
α-Carboxyl-ω-isocyanato poly(ethylene glycol) [HOOC-PEG-NCO]. Catalog Number: PG01410402SIN. Mfr. No.: 06020310602; 06020310606; 06020310609; 06020310612.Read more
Aa Peg Aa
SINOPEG
https://www.sinopeg.com › aa-peg-aa_sp
SINOPEG
https://www.sinopeg.com › aa-peg-aa_sp
α-Acryloyl-ω-carboxyl poly(ethylene glycol). Molecular Weight: 2KDa, 5KDa ... AA-PEG-MA · AA-PEG-NCO. α-Acryloyl-ω-isocyanato poly(ethylene glycol).Read more
COOH-PEG-NCO - CD Bioparticles
cd-bioparticles.net
https://www.cd-bioparticles.net › cooh-peg-nco
cd-bioparticles.net
https://www.cd-bioparticles.net › cooh-peg-nco
α-Carboxyl-ω-isocyanato poly(ethylene glycol) (MW: 2kDa, 3.5kDa, 5kDa, 10kDa, 20kDa). Catalog:CDA-2119. Unit Size: 100 mg; 500 mg; 1 g; 5 g.Read more
$80 delivery
CATALOG & PRICE
Advanced Biochemicals
https://advancedbiochemicals.com › 2017/03 › A...
Advanced Biochemicals
https://advancedbiochemicals.com › 2017/03 › A...
PDF
α-Carboxyl-ω-amino poly(ethylene glycol). Catalog #. Name and MW. Price ... α-Carboxyl-ω-isocyanato poly(ethylene glycol). Catalog #. Name and MW. Price.Read more
Synthesis of α,ω-Heterobifunctional Poly(ethylene glycol)s by ...
American Chemical Society
https://pubs.acs.org › doi
American Chemical Society
https://pubs.acs.org › doi
The most direct pathway to prepare functionalized PEGs is the anionic ring-opening polymerization of ethylene oxide using initiators or terminating agents.Read more
People also ask
What is PEG in Dr Pepper?
Poly (ethylene glycol) is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers. PEG is included in many or all formulations of the soft drink Dr Pepper, purportedly as an anti-foaming agent.
Polyethylene glycol - chemeurope.com
chemeurope.com
https://www.chemeurope.com › encyclopedia › Polyethy...
chemeurope.com
https://www.chemeurope.com › encyclopedia › Polyethy...
Web results
OH-PEG-COOH, α-hydroxyl-ω-carboxyl poly(ethylene glycol)
Biopharma PEG
https://www.biochempeg.com › product › OH-PEG-COOH
Biopharma PEG
https://www.biochempeg.com › product › OH-PEG-COOH
OH-PEG-COOH, also known as α-hydroxyl-ω-carboxyl poly(ethylene glycol), is a linear heterobifunctional PEG derivative with one hydroxyl group and one carboxyl ...Read more
$55 delivery
Synthesis and self-assembling properties of α,ω-hydroxy ...
ScienceDirect.com
https://www.sciencedirect.com › article › abs › pii
ScienceDirect.com
https://www.sciencedirect.com › article › abs › pii
by VS Kadam2008Cited by 12 — A carboxyl-capped PLGA–PEG–PLGA block copolymer (PLGA: poly(d,l-lactic acid-co-glycolic acid), PEG: poly(ethylene glycol)) was synthesized, and its self ...Read more
CPC Definition - Subclass C08G
United States Patent and Trademark Office (.gov)
https://www.uspto.gov › web › classification › cpc › html
United States Patent and Trademark Office (.gov)
https://www.uspto.gov › web › classification › cpc › html
#C8Gd : The addition of hydroxyethyl methacrylate (C08G 18/672) onto an isocyanate-terminated polyethylene glycol (C08G 18/4833) is classified as (C08G 18/672, ...Read more
EP1400550A1 - Branched polyalkylene glycols
Google Patents
https://patents.google.com › patent
Google Patents
https://patents.google.com › patent
The present invention provides a branched polyalkylene glycol wherein three or more single-chain polyalkylene glycols and a group having reactivity with an ...
r&d product portfolio
specific polymers
https://specificpolymers.com › uploads › 2022/03
specific polymers
https://specificpolymers.com › uploads › 2022/03
PDF
SP-4P-4-POLY(METH)ACRYLATE AMINE / ISOCYANATE / AZIDE / PROPARGYL. SP-4P-5 ... Product Name: Poly(ethylene glycol), α,ω-bis(carboxylic acid). CAS Number ...Read more