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    An AI Overview is not available for this searchCan't generate an AI overview right now. Try again later.
    AI Overview
    Cooling agent WS-23 (N,2,3-trimethyl-2-isopropylbutyramide) is a widely used, food-grade synthetic coolant that provides a refreshing chill without the minty taste of menthol. It is frequently added to candies, beverages, and oral care products. It offers a rapid, long-lasting cooling sensation compared to traditional agents. 
    Key Medical-Grade & Food-Safe Cooling Agents 
    • WS-23 (CAS 51115-67-4): Popular in food, beverage, and confectionery for a round, quick-hitting cooling sensation without odor, often used at 0.1% to 5.0% concentrations.
    • Menthol Crystals: Natural, high-purity cooling agent commonly used in pharmaceuticals, toothpaste, and confectionery.
    • WS-5 & WS-3: Known for having higher cooling strengths than WS-23.
    • ECOCOOL™: A series of cooling agents that provide intense, sustained, odorless, and colorless cooling, designed to be more effective than standard agents. 
    Common Applications 
    • Food & Confectionery: Hard candies, chewing gum, and breath fresheners.
    • Oral Care: Toothpaste and mouthwash.
    • Pharmaceuticals/Personal Care: Topicals and lozenges. 
    Reference Dosages
    Dosages depend on the application, ranging from 3–8 mg/kg in baked goods to as high as 75–3000 mg/kg in chewing gum. 
    Disclaimer: Ensure any chemical used is sourced from a reputable supplier ensuring food-grade or pharma-grade, such as Alfa Chemistry or similar providers, and adheres to local food safety regulations. 
    • Menthol Crystals | Premium Natural Cooling Agent for Food - Consolidated Chemical
      They are known for their cooling effect, minty aroma, and antimicrobial properties. Menthol crystals dissolve easily in alcohol, o...
      Consolidated Chemical
    • Cooling Agent WS-23 - Fluid Science
      Cooling Agent WS-23 is a synthetic chemical that's often used as a flavoring additive to create a cooling sensation without adding...
      Fluid Science
    • Videos about What is Food Cooling Enhancers Cool Taste ...
      Apr 12, 2026 — Food Cooling Enhancers Cool Taste WS23(WS-23) Coolant What's WS-23? Cooling Agent WS-23 is the latest in a long line of cooling ag...
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    • What to Know About Propylene Glycol in Foods
      Jun 21, 2024 — PG is found in many processed foods, including: * Flavoring extracts PG is also used in: * Cosmetics * Dog food * Bath products * ...
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      Food Additives Artificial Chemical Cooling Agent WS-23 Cooler For Candy Use What's WS-23? Cooling Agent WS-23 is the latest in a l...
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    • ECOCOOL™ MP - Pharma Excipients
      Ecocool products are available in different physical forms, including: * Pellets * Powders * Granules * Solutions Ecocool products...
      Pharma Excipients
    • Coolants in e-cigarettes are poorly researched: health impairments ...
      Nov 4, 2025 — Synthetic coolants such as WS-23, WS-3 and WS-5 are widely used in e-cigarettes. They are added to the liquids that are vaporised ...
      Bundesinstitut für Risikobewertung
    • WS-23, WS-5, WS-12, WS-3 vs Menthol for Food & Beverage
      Aug 6, 2025 — 🧊 WS-23: Clean, Smooth & Fast. WS-23 is one of the most popular cooling agents on the market. Cooling feel: Clean, flavourless, f...
      TasteNest
    • WS-23 30% Cooling Solution
      WS-23 is a cooling agent with little to no odor. Good for those who want a “cool or icy” flavor in their recipe, this offers a rou...
      Flavor Jungle
    • Coolant complex-5
      2. Oral Care Products Widely used in toothpaste and mouthwash to impart a long-lasting fresh and cooling effect. Added in oral str...
      Anshul Specialty Molecules Private Limited
    • Using WS-23 Cooling Agent in Hair/Scalp Products and Alternatives
      Jun 6, 2019 — WS-23 Cooling Agent (Methyl Diisopropyl Propionamide) is a cooling agent designed to provide a cooling sensation on the skin. Base...
      MySkinRecipes
    • FRESCOLAT X-COOL
      Frescolat X-Cool is generally regarded as safe for use in consumer products when used according to recommended guidelines. Regulat...
      Ataman Chemical
    • Benzyl Alcohol NF/FCC Food Grade
      This grade excels in cosmetics, food, fragrances, and pharmaceuticals, thanks to its stable odor profile and safety. It's also sui...
      Ingredient Depot
    • Menthol Crystals | Premium Natural Cooling Agent for Food - Consolidated Chemical
      They are known for their cooling effect, minty aroma, and antimicrobial properties. Menthol crystals dissolve easily in alcohol, o...
      Consolidated Chemical
    • Cooling Agent WS-23 - Fluid Science
      Cooling Agent WS-23 is a synthetic chemical that's often used as a flavoring additive to create a cooling sensation without adding...
      Fluid Science
    • Videos about What is Food Cooling Enhancers Cool Taste ...
      Apr 12, 2026 — Food Cooling Enhancers Cool Taste WS23(WS-23) Coolant What's WS-23? Cooling Agent WS-23 is the latest in a long line of cooling ag...
      0:24
      CELLmicrocosmos.org
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    Web results

    Medical Grade Food Additive Cooling Agent Ws-23 Powder


    Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
    https://www.cnherbflavor.com › medical-grade-food-add...
    Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
    https://www.cnherbflavor.com › medical-grade-food-add...
    Cooling agent WS-23 is for chewing gum ingredient can be long-lasting cooling effect for chewing gum, high temperature resistant and no bitter & spicy taste of ...Read more

    Cooling Agent WS-23


    Fluid Science
    https://www.fluidscienceltd.com › Products
    Fluid Science
    https://www.fluidscienceltd.com › Products
    Cooling Agent WS-23 is a flavouring additive, often used to create a cooling sensation in products such as E-Liquids, Food & Beverages, Chewing Gum, & more.
    £1,470.00 · In stock
    Missing: Medical ‎| Show results with: Medical

    Cooling Agent WS-23


    Alfa Chemistry
    https://ffc.alfa-chemistry.com › ... › Cooling Agents
    Alfa Chemistry
    https://ffc.alfa-chemistry.com › ... › Cooling Agents
    WS-23 is a synthetic food grade cooling agent known for its intense cooling sensation. It provides a similar cooling effect to menthol, but without the ...Read more
    Missing: Medical ‎Additive
    People also ask
    What is the most used cooling agent?
    Common cooling agents include water, salt water, ethan glycol aqueous solution, heat conduction oil, etc.

    What are the commonly used coolant? - ECHEMI


    Echemi
    https://www.echemi.com › community › what-are-the-co...
    Echemi
    https://www.echemi.com › community › what-are-the-co...
    Which chemical is used as a cooling agent?
    Today, most modern refrigerators take advantage of hydrofluorocarbon (HFC) and hydrocarbon (HC) refrigerants as cooling agents. Among them, the two most widely used are HFC-134a (also known as R-134a) and R-600a.Nov 15, 2025

    What gas is used as a cooling agent in refrigerators? - Croma


    Croma
    https://www.croma.com › unboxed › what-gas-is-used-as...
    Croma
    https://www.croma.com › unboxed › what-gas-is-used-as...
    What is the cooling agent in vapes?
    Synthetic coolants such as WS-23, WS-3 and WS-5 are widely used in e-cigarettes. They are added to the liquids that are vaporised and inhaled when consuming e-cigarettes.

    Coolants in e-cigarettes are poorly researched: health impairments ...


    bund.de
    https://www.bfr.bund.de › opinions › coolants-in-e-cigar...
    bund.de
    https://www.bfr.bund.de › opinions › coolants-in-e-cigar...
    What is the cooling agent in a refrigerator?
    An error has occurred. Please try again later.

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    Explain how the cooling cycle works
    Tell me more about HFC-134a
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    Web results

    Advantages and uses of current food additive cooling ...


    Aogubio
    https://www.aogubio.com › news › advantages-and-uses-...
    Aogubio
    https://www.aogubio.com › news › advantages-and-uses-...
    WS-23 is known for its refreshing, long-lasting cooling effect and is widely welcomed by the food and beverage industry. In this article, we'll explore the ...Read more

    Cooling Agent Ws-23 Powder


    Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
    https://www.cnherbflavor.com › cooling-agent_c1
    Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
    https://www.cnherbflavor.com › cooling-agent_c1
    Find best manufacturer of food additive cooling agent at Cnherbflavor.com. Our products mainly include cooling agent ws-23,ws-3,ws-12,etc.

    Overview of Cooling Agents


    Foreverest Resources Ltd
    https://foreverest.net › ... › Overview of Cooling Agents
    Foreverest Resources Ltd
    https://foreverest.net › ... › Overview of Cooling Agents
    Jul 19, 2024 — Pure natural cooling agents include essential oils like eucalyptus oil, camphor oil, and peppermint oil, with peppermint leaves being a prime example.Read more

    What to Know About Propylene Glycol in Foods


    WebMD
    https://www.webmd.com › ... › Reference
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    Propylene glycol comes in various grades for use in different applications: Food grade. Food-grade PG is found in products like seasonings, soup blends, teas, ...Read more

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    Sunland Chemical & Research
    4.4(5) · Chemical manufacturer
    5447 W San Fernando Rd · (818) 244-9600
    Closes soon · 3:30 PM
    "This beats east coast hands down lol…."
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    Synthetic Cooling Agents in US-marketed E-cigarette Refill ...


    PubMed Central (PMC) (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC9199944
    PubMed Central (PMC) (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC9199944
    by SV Jabba · 2022 · Cited by 86 — Synthetic cooling agents (WS-3/WS-23) were present in US-marketed E-cigarettes, at levels that may result in consumer exposures exceeding safety thresholds.Read more

    Menthol Crystals | Premium Natural Cooling Agent for Food


    Consolidated Chemical
    https://consolidated-chemical.com › Pesticide › Herbicide
    Consolidated Chemical
    https://consolidated-chemical.com › Pesticide › Herbicide
    Menthol Crystals are highly purified, naturally derived compounds obtained from peppermint essential oil. Known for their intense cooling effect.Read more
    $14.99 to $54.00 · In stock · $12.75 delivery · 30-day returns
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    Web results

    Cooling Agent Ws23(999+)


    Alibaba
    https://www.alibaba.com › ... › Chemical Auxiliary Agent
    Alibaba
    https://www.alibaba.com › ... › Chemical Auxiliary Agent
    WS-23 is a synthetic cooling agent widely used in consumer and pharmaceutical products for its potent, odorless, and non-irritating cooling effect. Unlike ...Read more
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