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    About 7,930 results (0.19s) 
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    An AI Overview is not available for this searchCan't generate an AI overview right now. Try again later.
    AI Overview
    mPEG-NCO (Methoxy Polyethylene Glycol Isocyanate) is a functionalized, linear PEG derivative with a reactive isocyanate (
    −NCOnegative cap N cap C cap O
    −𝑁𝐶𝑂
    ) group at one end. It is used for surface modification, drug delivery, and producing hydrogels, as the NCO group reacts with amines (
    −NH2negative cap N cap H sub 2
    −𝑁𝐻2
    ), hydroxyls (
    −OHnegative cap O cap H
    −𝑂𝐻
    ), or thiols (
    −SHnegative cap S cap H
    −𝑆𝐻
    ) to form stable covalent bonds. 
    Key Aspects of mPEG-NCO: 
    • Reactivity: The isocyanate group acts as a high-affinity coupling site for coupling, providing a bridge between hydrophilic MPEG chains and polymers or biological molecules.
    • Applications:
      • Drug Delivery: Used in developing amphiphilic copolymers for micelle formation and prodrug synthesis.
      • Surface Modification: Widely used in modifying nanoparticles or materials to increase hydrophilicity and stability.
      • Bioconjugation: Applied in coupling to PEGylated molecules.
    • Synthesis Intermediate: Methoxy polyethylene glycol is frequently reacted with diisocyanates like HDI or IPDI to create NCO-terminated mPEG, forming urea or urethane linkages.
    • Molecular Weights: Commercially available in a range of molecular weights, often including 2kDa, 5kDa, 10kDa, and higher. 
    Available products can be found through suppliers such as CD Bioparticles and Advanced BioChemicals. 
    • MPEG-NCO | SINOPEG Peg Derivative Functional Group
      Apr 21, 2025 — Methoxy polyethylene glycol isocyanate (mPEG-NCO) is a polyethylene glycol (PEG) derivative with an isocyanate (-NCO) active group...
      SINOPEG
    • mPEG-NCO - Advanced BioChemicals
      Advanced BioChemicals (ABC) offer mPEG-NCO with MW 2kDa, MW 3.5 kDa, MW 5kDa, MW 10kDa, MW 20kDa and MW 40kDa, in 1g, 5g and 10g p...
      Advanced Biochemicals
    • Synthesis and Dispersion of Organic Pigments by Amphiphilic ...
      Apr 5, 2026 — 2.1. Reagents and Instruments All chemical reagents used in this study were bought from Sinopharm Chemical Reagent Co., Ltd and we...
      IOPscience
    • MPEG-MA | SINOPEG Peg Derivative Functional Group
      Apr 9, 2025 — Emulsifier: Used as a natural non-toxic emulsifier in foods (such as dairy products) and cosmetics. * mPEG-NCO | SINOPEG peg deriv...
      SINOPEG
    • Novel AB 4 -Type CTBN-b-MPEG PU Micelle-like Amphiphilic ...
      Dec 20, 2012 — With increasing the molar ratios of MPEM-NCO to f-CTBN and Mn of hydrophilic MPEG blocks, the Mn of the copolymers is enhanced. Es...
      ACS Publications
    • Synthesis and characterization of a sterically stabilized ... - PubMed
      In the first step, methoxy-poly(ethylene glycol) (mPEG) (5 kDa) was combined with one isocyanate group of IPDI to form reactivated...
      National Institutes of Health (.gov)
    • MPEG-OMs | SINOPEG Peg Derivative Functional Group
      May 8, 2025 — mPEG-OMs | SINOPEG peg derivative functional group May 8,2025. ... mPEG: methoxy polyethylene glycol (methoxy PEG), providing hydr...
      SINOPEG
    • mPEG-NCO - CD Bioparticles
      CD Bioparticles provides mPEG-NCO, Monofunctional Linear PEGs with a PEG molecular weight of 3500 Da for drug delivery.
      www.cd-bioparticles.net
    • MPEG-NCO | SINOPEG Peg Derivative Functional Group
      Apr 21, 2025 — Methoxy polyethylene glycol isocyanate (mPEG-NCO) is a polyethylene glycol (PEG) derivative with an isocyanate (-NCO) active group...
      SINOPEG
    • mPEG-NCO - Advanced BioChemicals
      Advanced BioChemicals (ABC) offer mPEG-NCO with MW 2kDa, MW 3.5 kDa, MW 5kDa, MW 10kDa, MW 20kDa and MW 40kDa, in 1g, 5g and 10g p...
      Advanced Biochemicals
    • Synthesis and Dispersion of Organic Pigments by Amphiphilic ...
      Apr 5, 2026 — 2.1. Reagents and Instruments All chemical reagents used in this study were bought from Sinopharm Chemical Reagent Co., Ltd and we...
      IOPscience
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    Web results

    MPEG-NCO | SINOPEG Peg Derivative Functional Group


    SINOPEG
    https://www.sinopeg.com › blog › mpeg-nco-sinopeg-p...
    SINOPEG
    https://www.sinopeg.com › blog › mpeg-nco-sinopeg-p...
    Apr 21, 2025 — mPEG-NCO (Methoxy Polyethylene Glycol Isocyanate) is a polyethylene glycol (PEG) derivative with an isocyanate (-NCO) active group at the end, ...Read more

    Mpeg Nco


    SINOPEG
    https://www.sinopeg.com › blog › mpeg-nco_bk
    SINOPEG
    https://www.sinopeg.com › blog › mpeg-nco_bk
    Jan 23, 2025 — mPEG-NCO (Methoxy Polyethylene Glycol Isocyanate) is a polyethylene glycol (PEG) derivative with an isocyanate (-NCO) active group at the end, ...Read more

    mPEG-NCO - CD Bioparticles


    cd-bioparticles.net
    https://www.cd-bioparticles.net › mpeg-nco
    cd-bioparticles.net
    https://www.cd-bioparticles.net › mpeg-nco
    CD Bioparticles provides mPEG-NCO, Monofunctional Linear PEGs with a PEG molecular weight of 3500 Da for drug delivery.
    5.0(1)

    Novel Monomethoxy Poly(Ethylene Glycol) Modified ... - PMC


    National Institutes of Health (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC9921749
    National Institutes of Health (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC9921749
    by H Wang · 2023 · Cited by 2 — The mPEG modified hydroxylated tung oils were synthesized via the coupling reaction between hydroxyl groups of mPEG with various Mn and isocyanate groups in NCO ...Read more

    mPEG-NCO


    Advanced Biochemicals
    https://advancedbiochemicals.com › product › mpeg-nco
    Advanced Biochemicals
    https://advancedbiochemicals.com › product › mpeg-nco
    Advanced BioChemicals (ABC) offer mPEG-NCO with MW 2kDa, MW 3.5 kDa, MW 5kDa, MW 10kDa, MW 20kDa and MW 40kDa, in 1g, 5g and 10g packing sizes.
    $250.00 to $1,550.00

    Preparation and properties of monomethoxyl polyethylene ...


    ScienceDirect.com
    https://www.sciencedirect.com › article › abs › pii
    ScienceDirect.com
    https://www.sciencedirect.com › article › abs › pii
    by B Yang · 2022 · Cited by 25 — The NH2 groups of O-CMC were reacted with isocyanate-terminated MPEG (MPEG-NCO) to achieve MPEG-grafted O-CMC (MPEG-O-CMC). The chemical structures of the ...Read more

    Novel AB 4 -Type CTBN-b-MPEG PU Micelle-like Amphiphilic ...


    ACS Publications
    https://pubs.acs.org › doi
    ACS Publications
    https://pubs.acs.org › doi
    With increasing the molar ratios of MPEM-NCO to f-CTBN and Mn of hydrophilic MPEG blocks, the Mn of the copolymers is enhanced. Especially, in the case of the ...Read more

    Preparation of amphiphilic hyperbranched polyesteramides by ...


    Springer Nature Link
    https://link.springer.com › Polymer Bulletin
    Springer Nature Link
    https://link.springer.com › Polymer Bulletin
    by K Fang · 2008 · Cited by 16 — Second, MPEG-NCO was grafted onto the chains of hyperbranched polyesteramides (HP) by the reaction between the unreacted NCO group and the ...Read more

    Copolymerization of Chitosan Selectively Grafted by ...


    IEEE
    http://ieeexplore.ieee.org › document
    IEEE
    http://ieeexplore.ieee.org › document
    The selective grafted co polymerization of Chitosan with mPEG-NCO was conducted under heterogeneous conditions as suspension in dimethylformamide. The ...Read more

    The reaction of TDI and polyethylene glycol monocular ...


    Echemi
    https://www.echemi.com › community › the-reaction-of...
    Echemi
    https://www.echemi.com › community › the-reaction-of...
    Hello everyone, if I use polyethylene glycol monoethylene (monocular hydroxyl alcohol) and TDI reaction, I want to react to another -NCO reaction to the-NCO ...
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