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mPEG-NH2·HCl is

a methoxypoly(ethylene glycol) with a terminal primary amine group, supplied as a hydrochloride salt for increased stability. It is a common reagent in bioconjugation and drug delivery, used to attach the PEG chain to molecules containing carboxylic acids (via NHS ester activation), aldehydes, or ketones to form stable amide or other covalent bonds. The salt form makes it more stable and easier to handle as a solid.

Reactivity: The amine group readily reacts with activated carboxyl groups (such as NHS esters) to form stable amide bonds. It can also react with aldehydes and ketones.
Stability: The hydrochloride salt form enhances stability for storage and handling as a solid.
Biocompatibility: PEGylation with mPEG-NH2 can improve the water solubility, stability, and circulation time of biomolecules like proteins and drugs, and reduce their immunogenicity.

Drug delivery: Attaching mPEG to drugs to improve their pharmacokinetic properties.
Bioconjugation: Creating stable linkages between biomolecules, such as proteins and peptides.
Biomedical materials: Used in the preparation of hydrogels, microspheres, and other materials through polymerization and cross-linking.
Surface modification: Functionalizing surfaces for specific applications.
Gene therapy: Modifying gene vectors to enhance stability and efficiency.

m-PEG-NH2 HCl salt, MW 30,000 - BroadPharm
m-PEG-NH2 HCl salt, MW 30,000 is a PEGylation reagent with a protonated amine terminus which can couple with an activated NHS este...
BroadPharm
Methoxy PEG Amine, HCl Salt - JenKem Technology USA
m PEG Amine, HCl Salt, MW 550 - AxisPharm
mPEG Amine (methoxypolyethylene glycol amine), HCl Salt, MW 550 is a PEGylation reagent with free amine termini that reacts with a...
AxisPharm

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mPEG-NH2.HCl

Biopharma PEG

https://www.biochempeg.com › product › mPEG-NH2.H...

Biopharma PEG

https://www.biochempeg.com › product › mPEG-NH2.H...

Uses： Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis ...

$55 delivery

Methoxy PEG Amine, HCl Salt

JenKem Technology USA

https://jenkemusa.com › ... › Methoxy PEG Amines

JenKem Technology USA

https://jenkemusa.com › ... › Methoxy PEG Amines

The HCl salt form provides stability for the solid form of M-PEG-NH2. JenKem Technology offers Methoxy PEG Amine HCl with MW 2kDa (M-NH2-2000), MW 3kDa (M-NH2- ...

$50.00In stock

Methoxypoly(ethylene Glycol) Amine Hydrochloride Salt ...

SINOPEG

https://www.sinopeg.com › methoxypoly-ethylene-glyc...

SINOPEG

https://www.sinopeg.com › methoxypoly-ethylene-glyc...

Methoxypoly(ethylene glycol) amine hydrochloride salt（mPEG-NH2·HCl）is formed by a degradable linker connecting PEG polymer chain and thealkynyl, which is ...

mPEG-NH2-HCl

Abbexa

https://www.abbexa.com › mpeg-nh2-hcl

Abbexa

https://www.abbexa.com › mpeg-nh2-hcl

THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Research Articles on ...

$217.50In stock$50.75 delivery14-day returns

m-PEG-NH2 HCl salt, MW 10000

BroadPharm

https://broadpharm.com › product

BroadPharm

https://broadpharm.com › product

m-PEG-NH2 HCl salt, MW 10,000 is a linear methoxy PEGylation polymer with a primary amine, which can easily react with an NHS ester to form a stable amide bond.

$200.00 to $750.00In stock

m PEG Amine, HCl Salt, MW 550

AxisPharm

https://axispharm.com › ... › Amine › M PEG Amine

AxisPharm

https://axispharm.com › ... › Amine › M PEG Amine

It is a key intermediate in the preparation of specific functionalized activated MPEGs. The HCl salt form provides stability to M-PEG-NH2 in solid form.

$150.0030-day returns

mPEG-NH2

Advanced Biochemicals

https://advancedbiochemicals.com › product › mpeg-nh2

Advanced Biochemicals

https://advancedbiochemicals.com › product › mpeg-nh2

The HCl salt form provides stability for the solid form of mPEG-NH2. Advanced BioChemicals (ABC) offer mPEG-NH2 with MW 2kDa, MW 3.5 kDa, MW 5kDa, MW 10kDa ...

$150.00 to $1,150.00

Methoxypoly(ethylene glycol) amine hydrochloride salt [mPEG- ...

Amerigo Scientific

https://www.amerigoscientific.com › methoxypolyethyl...

Amerigo Scientific

https://www.amerigoscientific.com › methoxypolyethyl...

Methoxypoly(ethylene glycol) amine hydrochloride salt（mPEG-NH2·HCl）is formed by a degradable linker connecting PEG polymer chain and thealkynyl, which is ...

mPEG-NH2.HCl - CD Bioparticles

cd-bioparticles.net

https://www.cd-bioparticles.net › mpeg-nh2-hcl

cd-bioparticles.net

https://www.cd-bioparticles.net › mpeg-nh2-hcl

Augment your research on Biodegradable Polymers with the reliable mPEG-NH2.HCl from CD Bioparticles Drug Delivery.

mPEG-NH2 (CAT#: MPL0883K)

Creative Biolabs

https://www.creative-biolabs.com › ... › Phospholipid