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    HIV 1/ 2 Ab Rapid Test | Rapid Test Products | Athenese Dx
    HIV-1 & 2 rapid tests detect antibodies (and sometimes the p24 antigen for early detection) to both HIV types from blood or saliva, offering quick results (minutes to 20 mins) for screening in clinics or point-of-care settings, but positive rapid tests always need a confirmatory lab test for definitive diagnosis, with newer 4th-gen combo tests like Determine HIV-1/2 Ag/Ab Combo (Abbott) catching infections earlier than older antibody-only tests. 
    Types of Rapid Tests 
    • Antibody-Only (3rd Gen): Detects antibodies to HIV-1 & HIV-2 (e.g., INSTI HIV-1/HIV-2 or Accu-Tell HIV1/2 tests), great for screening but miss early acute infections.
    • Antigen/Antibody (4th Gen): Detects HIV-1 p24 antigen (appears before antibodies) and HIV-1/2 antibodies, allowing for earlier diagnosis of acute HIV-1 infection (e.g., Determine HIV-1/2 Ag/Ab Combo (Abbott)). 
    How They Work 
    • Uses immunochromatography on a small strip or card.
    • Checks for HIV-specific antibodies (IgG/IgM) and/or the p24 antigen.
    • Results in minutes (as fast as 60 seconds for some) using blood (fingerstick/venous), plasma, or oral fluid/saliva. 
    Key Features & Limitations 
    • Speed: Provides rapid screening results.
    • Early Detection: 4th-gen tests find acute HIV-1 infection sooner.
    • Confirmation Needed: A positive rapid screen requires a follow-up lab test (like a 4th gen lab assay or Western Blot) for confirmation.
    • Differentiation: Some differentiate HIV-1 from HIV-2, while Combo tests identify both infections. 
    Use Cases 
    • Point-of-care settings (clinics, labs, emergency care).
    • Screening individuals at risk or showing symptoms (weight loss, night sweats, fatigue).
    • Part of a multi-test diagnostic algorithm. 
    • HIV-1/2 Antigen and Antibodies, Fourth Generation, With Reflexes | Test Summary | Quest Diagnostics
      The HIV-1/2 Antigen and Antibodies, Fourth Generation, With Reflexes test is used to: * Screen for and diagnose HIV-1/HIV-2 infect...
      Quest Diagnostics
    • Determine HIV-1/2 Ag/Ab Combo | Abbott Point of Care
      Determine™ HIV-1/2 Ag/Ab Combo. The first FDA approved rapid point-of-care test that detects both HIV-1/2 antibodies and free HIV-
      globalpointofcare.abbott·
      7:55
    • World's Fastest HIV Antibody Test | #1 HIV Test
      The INSTI HIV-1/HIV-2 Antibody Test is a one-time use, rapid, visually read, flow-through immunoassay that detects antibodies to H...
      insti.com
    Show all
    • World's Fastest HIV Antibody Test | #1 HIV Test
      The INSTI HIV-1/HIV-2 Antibody Test is a one-time use, rapid, visually read, flow-through immunoassay that detects antibodies to H...
      insti.com
    • Determine HIV-1/2 Ag/Ab Combo - FDA
      Jan 30, 2022 — The Determine HIV-1/2 Ag/Ab Combo is intended for use as a point-of-care test to aid in the diagnosis of infection wit...
      Food and Drug Administration (.gov)
    • HIV-1/2 Antigen and Antibodies, Fourth Generation, With Reflexes | Test Summary | Quest Diagnostics
      The HIV-1/2 Antigen and Antibodies, Fourth Generation, With Reflexes test is used to: * Screen for and diagnose HIV-1/HIV-2 infect...
      Quest Diagnostics
    • HIV-1/HIV-2 Rapid Screen
      HIV-1/HIV-2 Rapid Screen * Does this test have other names? Rapid HIV antibody test. * What is this test? This test looks for HIV ...
      University of Rochester Medical Center
    • Determine HIV-1/2 Ag/Ab Combo | Abbott Point of Care
      Determine™ HIV-1/2 Ag/Ab Combo. The first FDA approved rapid point-of-care test that detects both HIV-1/2 antibodies and free HIV-
      globalpointofcare.abbott·
      7:55
    • Rapid Test - Clinical Info .HIV.gov
      A rapid HIV antibody test can detect HIV antibodies in blood or oral fluid in less than 30 minutes. There is also a rapid antigen/
      Clinical Info .HIV.gov
    • Package Insert - Multispot HIV-1/HIV-2 Rapid Test - FDA
      Mar 14, 2013 — Rapid Enzyme Immunoassay to be used as a diagnostic aid for the detection and differentiation of HIV-1 and HIV-2 antib...
      Food and Drug Administration (.gov)
    • Clinical diagnostic accuracy of the HIV rapid test ACCU-TELL anti- ...
      Jun 30, 2025 — Determine™ HIV-1/2 Ag/Ab Combo (Alere) is one the most used fourth-generation RDT in HIV screening. This test can be u...
      National Institutes of Health (.gov)
    • HIVDX - Overview: HIV-1 and HIV-2 Antigen and Antibody ...
      Routine serologic screening of patients at risk for HIV-1 or HIV-2 infection usually begins with an HIV-1/-2 antigen and/or antibo...
      Mayo Clinic Laboratories
    • HIV Antibody Test Using A Rapid HIV Card
      Jun 16, 2012 — hiv antibbody test using a rapid HIV card learning objectives the student is supposed to be able to describe the test ...
      YouTube·OER Africa
      3m
    • Rapid Anti-HIV (1&2) Test - InTec PRODUCTS, INC.
      The Advanced Quality Rapid Anti-HIV (1&2) Test is a colloidal gold enhanced immunochromatographic assay for the qualitative detect...
      InTec PRODUCTS, INC.
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    Determine HIV-1/2 Ag/Ab Combo


    Abbott Point of Care
    https://www.globalpointofcare.abbott › Home › Products
    Abbott Point of Care
    https://www.globalpointofcare.abbott › Home › Products
    It's the first antigen/antibody rapid point-of-care test that detects both HIV-1/2 antibodies and free HIV-1 p24 antigen on a single test strip.Read more
    HIV 1&2 subtype rapid tests from www.globalpointofcare.abbott
    Missing: subtype ‎| Show results with: subtype

    World's Fastest HIV Antibody Test | #1 HIV Test - INSTI


    insti.com
    https://insti.com › hiv-test
    insti.com
    https://insti.com › hiv-test
    The INSTI HIV-1/HIV-2 Antibody Test is a one-time use, rapid, visually read, flow-through immunoassay which detects antibodies to Human Immunodeficiency Virus ...Read more
    Missing: subtype ‎| Show results with: subtype

    HIV-1/HIV-2 Rapid Screen


    University of Rochester Medical Center
    https://www.urmc.rochester.edu › Encyclopedia
    University of Rochester Medical Center
    https://www.urmc.rochester.edu › Encyclopedia
    This test looks for HIV infection in your blood or saliva. HIV is the virus that causes AIDS. About 1 in 5 people who are infected with HIV don't know it.Read more
    Missing: subtype ‎| Show results with: subtype

    HIVDX - Overview: HIV-1 and HIV-2 Antigen and Antibody ...


    Mayo Clinic Laboratories
    https://www.mayocliniclabs.com › test-catalog › overview
    Mayo Clinic Laboratories
    https://www.mayocliniclabs.com › test-catalog › overview
    This test begins with HIV-1/-2 antigen and antibody screen by electrochemiluminescence immunoassay. If the screen result is reactive, then HIV-1/-2 antibody ...Read more
    Missing: subtype ‎| Show results with: subtype

    Determine HIV-1/2 Ag/Ab Combo


    Food and Drug Administration (.gov)
    https://www.fda.gov › approved-blood-products › deter...
    Food and Drug Administration (.gov)
    https://www.fda.gov › approved-blood-products › deter...
    Jan 31, 2022 — The Determine HIV-1/2 Ag/Ab Combo is intended for use as a point-of-care test to aid in the diagnosis of infection with HIV-1 and HIV-2, ...Read more
    Missing: subtype ‎| Show results with: subtype

    HIV 1 & 2 Test | In-Person HIV Testing - Quest Diagnostics


    questhealth.com
    https://www.questhealth.com › product › hiv-1-2-test-w...
    questhealth.com
    https://www.questhealth.com › product › hiv-1-2-test-w...
    This test detects HIV-1 and HIV-2 infections, as well as p24 antigens, using 4th generation HIV testing and can detect HIV infections in their early stages, ...
    HIV 1&2 subtype rapid tests from www.questhealth.com
    $85.00 · Free delivery
    Missing: subtype ‎| Show results with: subtype

    Evaluation of the Rapid Immunoassay Determine HIV 1/2 ...


    National Institutes of Health (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC179847
    National Institutes of Health (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC179847
    by GEL van den Berk · 2003 · Cited by 79 — The HIV 1/2 rapid test has proven to be a rapid, simple, and useful test for the detection of HIV antibodies.Read more
    Missing: subtype ‎| Show results with: subtype

    HIV-1/2 Antigen and Antibodies, Fourth Generation, With ...


    Quest Diagnostics
    https://testdirectory.questdiagnostics.com › test-guides
    Quest Diagnostics
    https://testdirectory.questdiagnostics.com › test-guides
    This test is used to screen for and diagnose HIV-1/HIV-2 infection (including acute infection) and to differentiate HIV-1 from HIV-2 infection.

    How accurate are rapid, point-of-care tests for HIV?


    Aidsmap
    https://www.aidsmap.com › about-hiv › how-accurate-a...
    Aidsmap
    https://www.aidsmap.com › about-hiv › how-accurate-a...
    Mar 15, 2022 — Most rapid tests, with the exception of the Determine HIV Early Detect and Determine HIV-1/2 cannot detect p24 antigen. The accuracy of point-of ...Read more
  • Key points
  • The accuracy of different rapid...
  • Window periods of rapid tests

    • One Step Anti-HIV (1&2) Test


    InTec PRODUCTS, INC.
    https://www.intecasi.com › one-step-anti-hiv-1-2-test_p9
    InTec PRODUCTS, INC.
    https://www.intecasi.com › one-step-anti-hiv-1-2-test_p9
    The One Step Anti-HIV (1&2) Test is a colloidal gold enhanced rapid immunochromatographic assay for qualitative detection of antibodies to Human Immunodeficiency ...Read more
    Missing: subtype ‎| Show results with: subtype

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