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Propenyl-PEG-NH2 (α-Propenyl-ω-amino poly(ethylene glycol)) is a bifunctional PEG derivative featuring a propenyl group and a terminal amine group. It is used in bioconjugation, surface modification, and as a PEGylation reagent to enhance water solubility and reduce immune recognition, commonly found in molecular weights from 2KDa to 20KDa.
Key Aspects of Propenyl-PEG-NH2:
- Structure: Linear PEG with a propenyl group on one end () and an amino group () on the other, creating a versatile reagent for selective functionalization.
- Applications:
- Surface Modification: The propenyl group can be used for further functionalization, while the amine readily reacts with NHS esters or other electrophiles, often used to modify surfaces or create functional coatings.
- Drug Delivery & Bioconjugation: Improves solubility and stability of active compounds, including proteins and peptides.
- PEGylation: Used to increase the molecular weight of compounds to create "stealth" effects, reducing immune recognition.
- Availability: Typically available from suppliers like Sinopeg
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Web results
Propenyl-PEG-NH2 Manufacturer
SINOPEG
https://www.sinopeg.com › propenyl-peg-nh2_p454
SINOPEG
https://www.sinopeg.com › propenyl-peg-nh2_p454
We are professional China Propenyl-PEG-NH2 company,manufacturer Propenyl-PEG-NH2 many years.All PEGs products acquired ISO-9001and ISO-13485 certified.
Propenyl Peg Nh2
SINOPEG
https://www.sinopeg.com › propenyl-peg-nh2_sp
SINOPEG
https://www.sinopeg.com › propenyl-peg-nh2_sp
α-Propenyl-ω-amino poly(ethylene glycol). Molecular Weight: 2KDa, 5KDa, 10KDa, 20KDa. Package Size: 1g/bottle, 10g/bottle, 100g/bottle.
Nh2-peg-nh2
Sigma-Aldrich
https://www.sigmaaldrich.com › search › nh2-peg-nh2
Sigma-Aldrich
https://www.sigmaaldrich.com › search › nh2-peg-nh2
nh2-peg-nh2 ; Poly(ethylene glycol) methyl ether amine average Mn 500 · 767565 · Poly(ethylene glycol) methyl ether amine · average Mn 500.Read more
Poly PEG, PEG polymer, PEGylation Reagent, 5k, 10k, 20k
BroadPharm
https://broadpharm.com › peg-linkers › poly-peg
BroadPharm
https://broadpharm.com › peg-linkers › poly-peg
Poly PEG or PEG polymer is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications.Read more
PEGylation in Pharmaceutical Development: Current Status ...
National Institutes of Health (.gov)
https://pmc.ncbi.nlm.nih.gov › articles › PMC11390148
National Institutes of Health (.gov)
https://pmc.ncbi.nlm.nih.gov › articles › PMC11390148
by KR Santhanakrishnan2024Cited by 95 — Pharmaceutical companies use PEG with a molecular weight (MW) of over 20 kDa to create a "stealth" effect, reducing immune system recognition ...Read more
Linear Heterofunctional PEG
Alfa Chemistry
https://vaccinelab.alfa-chemistry.com › products › linear-...
Alfa Chemistry
https://vaccinelab.alfa-chemistry.com › products › linear-...
Vaccine Lab / Alfa Chemistry can provide Linear Heterofunctional PEG for customers.
Multifunctionalized polyethylene glycol derivative and ...
Google Patents
https://patents.google.com › patent
Google Patents
https://patents.google.com › patent
The derivative has an H-shaped structure as represented by formula (1) and comprises one linear core LPEG and four PEG branch chains, where n 1, n 2, n 3, and n ...Read more
heterobifunctional pegs
JenKem Technology USA
https://jenkemusa.com › heterobifunctional-pegs
JenKem Technology USA
https://jenkemusa.com › heterobifunctional-pegs
Apr 10, 2026 — JenKem Technology provides high quality heterobifunctional polyethylene glycol derivatives (PEGs) with high purity and low polydispersity.Read more
People also ask
Is peg natural or synthetic?
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.Oct 29, 2015
Polyethylene glycol: Uses, Interactions, Mechanism of Action | DrugBank
DrugBank
https://go.drugbank.com › drugs
DrugBank
https://go.drugbank.com › drugs
Is polyethylene glycol a peg?
Polyethylene glycol (PEG) is a product with industrial and pharmaceutical uses. Since many PEG compounds are hydrophilic, industrially, they are utilized in cosmetic products as surfactants, emulsifiers, cleansing agents, humectants, and skin conditioners. [1] As a medication, PEG is a part of the laxative class.
Polyethylene Glycol - StatPearls - NCBI Bookshelf
NCBI - NIH
https://www.ncbi.nlm.nih.gov › books › NBK557652
NCBI - NIH
https://www.ncbi.nlm.nih.gov › books › NBK557652
Web results
Alkyne-PEG2-NH2 | CAS:944561-44-8
Biopharma PEG
https://www.biochempeg.com › product › Alkyne-PEG2...
Biopharma PEG
https://www.biochempeg.com › product › Alkyne-PEG2...
Alkyne-PEG2-NH2 is a linear PEG reagent featuring an alkyne functional group (-C≡CH) and an amino group (-NH2). It is a non-cleavable ADC linker.Read more
$100.00$55 delivery
