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    Bis(2,4,4-trimethylpentyl)phosphinic acid (CAS 83411-71-6) is a
    colorless to pale yellow, viscous liquid, often known as the active component in the industrial extractant Cyanex 272. Primarily used in hydrometallurgy, it is specialized for cobalt-nickel separation and extracting rare earth metals, with a density of ~0.92 g/cm³ and high lipophilicity. 
    Key Properties 
    • Appearance: Liquid (colorless to pale yellow)
    • CAS Number: 83411-71-6
    • Molecular Formula:
      𝐶16
      𝐻35
      𝑂2𝑃
    • Density:
      0.916
      −0.92
      g/cm3
      at 20-24°C
    • Flash Point:
      108
      °C
    • Refractive Index:
      1.4601.460
      1.460
      at
      20
      °C
    • Solubility: Typically used with hydrocarbon diluents (e.g., kerosene) 
    Industrial and Scientific Applications 
    • Cobalt/Nickel Separation: Used extensively in the mining industry to separate Co from Ni in sulfate solutions.
    • Rare Earth Separation: Used for extracting gallium (Ga), indium (In), molybdenum (Mo), and zirconium (Zr).
    • Nanocrystal Synthesis: Functions as a surface passivating ligand for CdSe and CdTe nanocrystals. 
    Safety and Handling 
    • Hazard Statements: Causes serious eye irritation (H319) and is very toxic to aquatic life with long-lasting effects (H410).
    • PPE: Requires protective goggles, gloves, and clothing to prevent skin and eye contact.
    • Storage: Store in a cool, well-ventilated area in tightly closed containers. 
    Common Commercial Forms 
    • Cyanex 272: A commercial product typically containing 85–87% of this acid.
    • Form: Usually supplied as technical grade, roughly 90%. 
    • Bis(2,4,4-Trimethylpentyl)-Phosphinic Acid Cyanex 272 For Nickel ...
      It is also suitable for the extraction and separation of rare earth, gallium (Ga), indium (In), molybdenum (Mo), germanium (Ge), z...
      www.blitchem.com
    • Bis(2,4,4-trimethylpentyl)phosphinic acid CAS 83411-71-6
      Application. Extractant, can be used for nickel cobalt separation, rare earth separation.
      www.unilongmaterial.com
    • bis(2,4,4-trimethylpentyl) phosphinic acid - Echemi
      * 37.3. * 4.6. * Density: 0.92 g/cm3 @ Temp: 24 °C. * 269.9°C at 760 mmHg. * 117ºC. * 1.502.
      Echemi
    Show all
    • Bis(2,4,4-Trimethylpentyl)-Phosphinic Acid Cyanex 272 For Nickel ...
      It is also suitable for the extraction and separation of rare earth, gallium (Ga), indium (In), molybdenum (Mo), germanium (Ge), z...
      www.blitchem.com
    • Bis(2,4,4-trimethylpentyl)phosphinic acid CAS 83411-71-6
      Application. Extractant, can be used for nickel cobalt separation, rare earth separation.
      www.unilongmaterial.com
    • bis(2,4,4-trimethylpentyl) phosphinic acid - Echemi
      * 37.3. * 4.6. * Density: 0.92 g/cm3 @ Temp: 24 °C. * 269.9°C at 760 mmHg. * 117ºC. * 1.502.
      Echemi
    • bis(2,4,4-trimethylpentyl) phosphinic acid | China - ChemicalBook
      * Appearance. * Colorless to pale yellow liquid. * Colorless to pale yellow liquid.
      ChemicalBook
    • BIS(2,4,4-TRIMETHYLPENTYL)PHOSPHINIC ACID
      Jan 13, 2026 — 27661-42-3 Chemical Name: BIS(2,4,4-TRIMETHYLPENTYL)PHOSPHINIC ACID Synonyms DIISOOCTYLPHOSPHINIC ACID;technical, ~90% (T);Phosphi...
      ChemicalBook
    • Identification and characterisation of a Cyanex 272 degradation product ...
      Jun 15, 2010 — Cyanex 272 is a commercial extractant containing bis(2,4,4-trimethylpentyl)phosphinic acid (R2P(O)OH, where R = 2,4,4-trimethylpen...
      ScienceDirect.com
    • CAS 83411-71-6 (bis-(2,4,4-Trimethylpentyl)phosphinic acid)
      bis-(2,4,4-Trimethylpentyl)phosphinic acid. Catalog NO.: B1370-078126 CAS NO.: 83411-71-6 Brand: BOC Sciences. Category. Molecular...
      BOC Sciences
    • Safety Data Sheet - Biosynth
      May 5, 2022 — Do not allow to enter into soil/subsoil. Do not allow to enter into surface water or drains. Ensure all waste water is collected a...
      Biosynth
    • Bis(2,4,4-trimethylpentyl)phosphinic Acid | 83411-71-6
      H319 : Causes serious eye irritation. H410 : Very toxic to aquatic life with long lasting effects. ... P501 : Dispose of contents/
      Tokyo Chemical Industry
    • bis(2,4,4-trimethylpentyl)phosphinic acid - ChemicalBook
      Usage And Synthesis ... Diisooctylphosphinic Acid functions as a surface passivating ligand in the synthesis of magic-sized cadmiu...
      ChemicalBook
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    Bis(2,4,4-trimethylpentyl)phosphinic Acid | 83411-71-6


    Tokyo Chemical Industry Co., Ltd.
    https://www.tcichemicals.com › ...
    Tokyo Chemical Industry Co., Ltd.
    https://www.tcichemicals.com › ...
    Bis(2,4,4-trimethylpentyl)phosphinic Acid; Product No: B6762; CAS RN: 83411-71-6; Purity: >95.0%(T); Appearance: Colorless to Light yellow clear liquid, min.

    Bis(2,4,4-trimethylpentyl)phosphinic acid | 83411-71-6


    Sigma-Aldrich
    https://www.sigmaaldrich.com › bidepharmatech
    Sigma-Aldrich
    https://www.sigmaaldrich.com › bidepharmatech
    Bis(2,4,4-trimethylpentyl)phosphinic acid; CAS Number: 83411 ... Solid or semi-solid or lump or liquid. Safety Information. hstatements. H302 ...Read more

    Bis(2,4,4-trimethylpentyl)phosphinic acid | 83411-71-6


    Biosynth
    https://www.biosynth.com › Research Chemicals
    Biosynth
    https://www.biosynth.com › Research Chemicals
    Bis(2,4,4-trimethylpentyl)phosphinic acid (diisooctylphosphinic acid) is a slightly water soluble compound which has a variety of applications.Read more
    $355.17

    Bis(2,4,4-trimethylpentyl)phosphinic acid, min. 85% ...


    Strem Catalog
    https://www.strem.com › product
    Strem Catalog
    https://www.strem.com › product
    Bis(2,4,4-trimethylpentyl)phosphinic acid, min. 85%, CYTOP® 501 CAS Number 83411-71-6 | Molecular Formula C₁₆H₃₅O₂P | Chemical Formula C₁₆H₃₅O₂P | Chemical ...
    $106.00 to $421.00 · In stock · Free delivery
    Missing: liquid ‎| Show results with: liquid

    Bis(2,4,4-trimethylpentyl)phosphinic acid - PubChem


    National Institutes of Health (NIH) | (.gov)
    https://pubchem.ncbi.nlm.nih.gov › compound › Bis_2...
    National Institutes of Health (NIH) | (.gov)
    https://pubchem.ncbi.nlm.nih.gov › compound › Bis_2...
    Phosphinic acid, P,P-bis(2,4,4-trimethylpentyl)-: Does not have an individual approval but may be used as a component in a product covered by a group standard.Read more

    CAS 83411-71-6 (bis-(2,4,4-Trimethylpentyl)phosphinic acid)


    BOC Sciences
    https://www.bocsci.com › ... › Intermediates
    BOC Sciences
    https://www.bocsci.com › ... › Intermediates
    bis-(2,4,4-Trimethylpentyl)phosphinic acid is a compound utilized in the biomedical sphere for its potential in treating organophosphate poisoning.Read more
    $499.00 · Free delivery · 30-day returns

    BIS(2,4,4-TRIMETHYLPENTYL)PHOSPHINIC ACID


    ChemicalBook
    https://www.chemicalbook.com › ... › CAS DataBase List
    ChemicalBook
    https://www.chemicalbook.com › ... › CAS DataBase List
    Jan 13, 2026 — BIS(2,4,4-TRIMETHYLPENTYL)PHOSPHINIC ACID Properties: Density 0.916 g/mL at 20 °C (lit.) Flash point 108 °C.Read more

    Bis(2,4,4-trimethylpentyl)phosphinic acid Safety Data Sheets


    Echemi
    https://www.echemi.com › sds › bis244-trimethyl-penty...
    Echemi
    https://www.echemi.com › sds › bis244-trimethyl-penty...
    Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable ...Read more

    Safety Data Sheet: Bis(2,4,4-trimethylpentyl)phosphinic acid


    Carl ROTH
    https://www.carlroth.com › medias
    Carl ROTH
    https://www.carlroth.com › medias
    PDF
    May 21, 2025 — ICAO-TI. Environmentally hazardous substance, liquid,. n.o.s.. Technical name. Bis(2,4,4-trimethylpentyl)phosphinic acid. 14.3 Transport hazard ...Read more

    Bulk Bis (2 4 4-trimethylpentyl) Phosphinic Acid 83411-71-6


    Fitech Material
    https://www.fitechem.com › Chemicals
    Fitech Material
    https://www.fitechem.com › Chemicals
    Bis(2,4,4-trimethylpentyl)phosphonic acid, a colorless to pale yellow liquid. Acid phosphonic acid extractant, originally developed for the separation of nickel ...Read more
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