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    An AI Overview is not available for this searchCan't generate an AI overview right now. Try again later.
    AI Overview
    WS-3 (N-ethyl-p-menthane-3-carboxamide) is a popular, odorless, and flavorless synthetic cooling agent used to provide a clean, sharp, and immediate "icy" sensation without the strong minty taste of menthol. Often referred to as a "koolada" compound, it is widely utilized in fruit-flavored e-liquids, confectionery, and beverages to enhance freshness. 
    Key Characteristics and Uses of WS-3: 
    • Cooling Profile: Unlike WS-23, which provides a faster, mouth-filling cool, WS-3 delivers a sharp, immediate, and long-lasting cooling effect, primarily felt at the back of the tongue and mouth.
    • Applications: It is common in, but not limited to, fruit-flavored e-liquids, oral nicotine pouches (e.g., Zyn Chill), mints, chewing gum, and personal care products.
    • Flavor Impact: WS-3 has a minimal, nearly non-existent odor and taste, allowing the fruit flavor to remain clean without being masked by mint.
    • Dosage: It is often sold as a concentrated solution (e.g., 10% in propylene glycol) and used in small concentrations, sometimes as low as
      10
      −100
      mg/kg
      .       
    Safety and Regulatory Notes: 
    • Safety Standards: WS-3 is recognized as safe for food and cosmetic use at regulated levels.
    • Safety Warning: Some studies suggest that when used in vaping products, it may be inhaled at levels exceeding safety guidelines, prompting scrutiny on its use in high concentrations.
    • CAS/FEMA: CAS # 39711-79-0, FEMA # 3455.
    • Where to Buy: Products can be found through various chemical suppliers, such as Flavor Jungle's WS-3 solution. 
    It is frequently used alongside other cooling agents to create specific, nuanced, refreshing experiences in commercial products. 
    • Koolada Solution (WS-3)
      WS-3, also known as Koolada, is a 10% propylene glycol solution that is often used as a cooling agent. It has many uses, including...
      Flavor Jungle
    • Symcool® Cooling Agents - Symrise
      It has potential for use in mint flavors in oral care applications as well as confectionary and chewing gum depending on dosage le...
      Symrise
    • WS-3 N-ethyl 2-isopropyl-5-methylcyclohexanecarboxamide
      Functional use(s) - flavoring agents. Has a minty type odor and an cooling type flavor. ... WS 3 · Shanghai Vigen Fine Chemical · ...
      The Good Scents Company
    • SYNTHETIC COOLING AGENT IN ORAL NICOTINE POUCH PRODUCTS MARKETED AS “FLAVOR-BAN APPROVED” - PMC
      The study found that: * **Zyn Chill** contains WS-3, an odorless synthetic cooling agent. * **Zyn Chill** activates the cold/menth...
      National Institutes of Health (.gov)
    • Potentially dangerous synthetic cooling agents are used at high ...
      May 15, 2022 — Synthetic cooling agents were found not only in mint- or menthol-flavored products, but in fruit- and candy-flavored products, inc...
      EurekAlert!
    • WS-3 Cooling Agent: Applications, Benefits, and Formulation Guidelines
      May 9, 2025 — Unlike WS-23, WS-3 produces a sharp, immediate cooling sensation that peaks quickly and gradually tapers. While it carries a sligh...
      Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
    • Cooling Agent WS-3 - Titanos Group
      Cooling Agent WS-3. WS-3 is a white powder crystal, used as a cooling agent for skin and lipstick. It is performed as a cooling ag...
      Titanos Group
    • Koolada Solution (WS-3)
      WS-3, also known as Koolada, is a 10% propylene glycol solution that is often used as a cooling agent. It has many uses, including...
      Flavor Jungle
    • Symcool® Cooling Agents - Symrise
      It has potential for use in mint flavors in oral care applications as well as confectionary and chewing gum depending on dosage le...
      Symrise
    • WS-3 N-ethyl 2-isopropyl-5-methylcyclohexanecarboxamide
      Functional use(s) - flavoring agents. Has a minty type odor and an cooling type flavor. ... WS 3 · Shanghai Vigen Fine Chemical · ...
      The Good Scents Company
    • SYNTHETIC COOLING AGENT IN ORAL NICOTINE POUCH PRODUCTS MARKETED AS “FLAVOR-BAN APPROVED” - PMC
      The study found that: * **Zyn Chill** contains WS-3, an odorless synthetic cooling agent. * **Zyn Chill** activates the cold/menth...
      National Institutes of Health (.gov)
    • Potentially dangerous synthetic cooling agents are used at high ...
      May 15, 2022 — Synthetic cooling agents were found not only in mint- or menthol-flavored products, but in fruit- and candy-flavored products, inc...
      EurekAlert!
    • WS-3 Cooling Agent: Applications, Benefits, and Formulation Guidelines
      May 9, 2025 — Unlike WS-23, WS-3 produces a sharp, immediate cooling sensation that peaks quickly and gradually tapers. While it carries a sligh...
      Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
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    My Ad Center

    Web results

    Cooling Agent WS-3 - Koolada Flavor Concentrate - Vegan


    Amazon.com
    https://www.amazon.com › ...
    Amazon.com
    https://www.amazon.com › ...
    Experience the subtle freshness of our liquid Cooling Agent WS-3! Ideal for desserts; drinks and baked goods. Vegan; allergen-free and versatile.
    People also ask
    What is the flavor of WS-3?
    Unlike WS-23, WS-3 produces a sharp, immediate cooling sensation that peaks quickly and gradually tapers. While it carries a slight minty note, this flavor is milder than menthol, making it suitable for applications where a refreshing hint complements the product profile.May 9, 2025

    WS-3 Cooling Agent: Applications,Benefits,and Formulation ...


    Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
    https://www.cnherbflavor.com › blog › ws-3-cooling-ag...
    Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
    https://www.cnherbflavor.com › blog › ws-3-cooling-ag...
    Is WS-3 safe?
    Conclusions. Synthetic cooling agents (WS-3/WS-23) were present in US-marketed E-cigarettes, at levels that may result in consumer exposures exceeding safety thresholds set by regulatory agencies.

    Synthetic Cooling Agents in US-marketed E-cigarette Refill ...


    PMC - NIH
    https://pmc.ncbi.nlm.nih.gov › articles › PMC9199944
    PMC - NIH
    https://pmc.ncbi.nlm.nih.gov › articles › PMC9199944
    What is the difference between WS-23 and WS-3?
    An error has occurred. Please try again later.

    Ask anything in AI Mode

    Summarize the key differences
    Explain how WS-23 works
    Tell me more about WS-3
    What is WS-3 used for?
    WS-3 is one of the most used cooling agents in the market and it's known for its clean immediate cooling impact and has been found to cool primarily at the roof of the mouth, the back of the mouth and the back of the tongue.

    Symcool® Cooling Agents - Symrise


    Symrise
    https://www.symrise.com › symrise-symcool-A4-pages-eng
    Symrise
    https://www.symrise.com › symrise-symcool-A4-pages-eng

    Web results

    Koolada Solution (WS-3)


    Flavor Jungle
    https://flavorjungle.com › ... › Koolada Solution (WS-3)
    Flavor Jungle
    https://flavorjungle.com › ... › Koolada Solution (WS-3)
    Applications: Multi-Purpose flavorings have a many uses, including aromatherapy, perfumes, fragrance, potpourri, and "scratch and sniff" applications.Read more
    Fruit Flavor WS-3 from flavorjungle.com

    WS-3 Cooling Agent: Applications,Benefits,and ...


    Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
    https://www.cnherbflavor.com › blog › ws-3-cooling-ag...
    Anhui Chinaherb Flavors&Fragrances Co.,Ltd.
    https://www.cnherbflavor.com › blog › ws-3-cooling-ag...
    May 9, 2025 — Unlike WS-23, WS-3 produces a sharp, immediate cooling sensation that peaks quickly and gradually tapers. While it carries a slight minty note, ...Read more

    WS-23, WS-5, WS-12, WS-3 vs Menthol for Food & Beverage


    TasteNest
    https://www.tastenest.com.au › post › cooling-agents-ws...
    TasteNest
    https://www.tastenest.com.au › post › cooling-agents-ws...
    Aug 6, 2025 — That's where flavourless cooling agents like WS-23, WS-5, WS-3, and WS-12 come in. These advanced coolants deliver a powerful chill, without ...Read more

    WS-3 N-ethyl 2-isopropyl-5-methylcyclohexanecarboxamide


    The Good Scents Company
    https://www.thegoodscentscompany.com › data
    The Good Scents Company
    https://www.thegoodscentscompany.com › data
    Functional use(s) - flavoring agents. Has a minty type odor and an cooling type flavor ... Useful in mint, red fruit, other fruits. TCI AMERICA. For ...Read more
  • Organoleptics
  • Suppliers
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  • Blenders

    • The role of synthetic coolants, WS-3 and WS-23, in ...


    ScienceDirect.com
    https://www.sciencedirect.com › science › article › pii
    ScienceDirect.com
    https://www.sciencedirect.com › science › article › pii
    by S Yogeswaran · 2022 · Cited by 20 — Synthetic cooling agents (WS-23 and WS-3) provide a cooling sensation. Coolants in e-cigarettes modify acellular and ROS levels in lung epithelial cells.Read more

    Cooling Agent WS-3


    Alfa Chemistry
    https://ffc.alfa-chemistry.com › ... › Cooling Agents
    Alfa Chemistry
    https://ffc.alfa-chemistry.com › ... › Cooling Agents
    Has a strong cool flavor activity, no menthol bitter, spicy feeling, no burning, numbness and other effects, can produce impact, fresh, longer aroma. Has a long ...Read more

    Liquid WS-3 - Sasami


    sasami.de
    https://sasami.de › Cooling-Agents › Liquid-WS-3
    sasami.de
    https://sasami.de › Cooling-Agents › Liquid-WS-3
    WS-3 ensures a pleasant, refreshing drinking experience with every sip.Desserts: Ideal for ice cream, sorbets, puddings or fruit mousse. The cooling highlights ...Read more

    Questions about flavors. : r/DIY_eJuice


    Reddit · r/DIY_eJuice
    20+ comments · 4 years ago
    Reddit · r/DIY_eJuice
    20+ comments · 4 years ago
    For minty, there are plenty of good mints, FW Menthol for Menthol and Koolada (WS-3) for icy with a mentholy taste. I prefer WS-23 and FA Polar ...Read more

    SYNTHETIC COOLING AGENT IN ORAL NICOTINE POUCH ...


    National Institutes of Health (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC10753027
    National Institutes of Health (.gov)
    https://pmc.ncbi.nlm.nih.gov › articles › PMC10753027
    Chemical analysis demonstrated that Chill exclusively contained WS-3, an odourless synthetic cooling agent, while mint-flavoured ONPs contained WS-3 together ...Read more
    People also search for
    WS-3 cooling agent side effects
    WS-23 cooling agent
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    WS-5 Cooling Agent
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    WS-23 buy
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    Concentrate Flavors

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