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Carbopol® 971P NF is a lightly cross-linked, high-molecular-weight polyacrylic acid polymer supplied as a white powder. It is used in pharmaceuticals as a thickener, suspending agent, and binder, particularly prized for its ability to create bioadhesive, low-viscosity, long-flow gels and provide controlled drug release in oral or mucosal formulations.
Key Features and Benefits
- Controlled Release: Provides effective drug release control in tablets, often preferred for its efficiency in drug matrix formulation compared to more highly cross-linked alternatives.
- Rheology Modification: Produces long-flow (flowable) gels, ideal for consistent, smooth oral liquids, lotions, and suspensions.
- Bioadhesion: Excellent mucoadhesive properties make it suitable for oral, topical, and ophthalmic drug delivery systems.
- Stability: Stable over a wide pH range and compatible with many active pharmaceutical ingredients (APIs).
Typical Applications and Usage
Comparison to Other Carbopol Polymers
- Carbopol 971P vs. 974P: 971P is lightly cross-linked, offering lower viscosity and better drug release control in some matrices compared to the highly cross-linked, higher-viscosity 974P.
- Carbopol 971P vs. 71G: 971P is a fine powder, while 71G is a granular form of the same polymer, designed to improve handling and flow for direct compression tablets.
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Carbopol® 971P NF Polymer
Lubrizol
https://www.lubrizol.com › products › detail-pages › ca...
Lubrizol
https://www.lubrizol.com › products › detail-pages › ca...
Carbopol® 971P NF polymer is used in oral and mucosal contact applications such as extended/controlled release tablets, oral liquids and suspension and ...
Carbopol® 971P NF Polymer
Pharma Excipients
https://www.pharmaexcipients.com › Shop
Pharma Excipients
https://www.pharmaexcipients.com › Shop
Carbopol 971P NF polymer is used in oral and mucosal contact applications such as extended/controlled release tablets, oral liquids and suspension and ...Read more
CARBOPOL 971P NF - LUBRIZOL
IMCD US
https://www.imcdus.com › product › carbopol-971p-nf
IMCD US
https://www.imcdus.com › product › carbopol-971p-nf
CARBOPOL® 971P NF polymer is a thickener and rheology modifier with long flow commonly used in the pharmaceutical industry. It also has bioadhesive and ...Read more
Carbomer /Carbopol 974P, 971P, 934P and 71G
nmcarbomer.com
https://www.nmcarbomer.com › carbomer-carbopol-974...
nmcarbomer.com
https://www.nmcarbomer.com › carbomer-carbopol-974...
Carbomers as rheological modifier, have been extensively applied in personal care products, pharmaceutical field, and another industrial field.Read more
Nasal toxicological investigations of Carbopol 971P ...
National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
by MI Ugwoke2000Cited by 56 — Due to the severe inflammation caused by Carbopol 971P with and without apomorphine, we conclude that this polymer is not a suitable carrier for intranasal ...
Carbopol® 971P NF Polymer
Essential Ingredients
https://www.essentialingredients.com › NO-Cb971PNF-48
Essential Ingredients
https://www.essentialingredients.com › NO-Cb971PNF-48
Bioadhesive agent; Extended release modifier. Additional Features: Thickener and rheology modifier; Emulsion and suspension stabilizer; Taste masking agent ...Read more
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Web results
CARBOPOL® POLYMERS FORMULATION AND ...
Pharma Excipients
https://www.pharmaexcipients.com › 2020/08 › L...
Pharma Excipients
https://www.pharmaexcipients.com › 2020/08 › L...
PDF
Lightly crosslinked Carbopol polymers (971P NF) tend to be more efficient in controlling drug release than highly crosslinked Carbopol polymers (974P NF).Read more
16 pages
Processing of Extended Release Tablets Containing ...
Freund Global
https://www.freund-vector.com › Technical Papers
Freund Global
https://www.freund-vector.com › Technical Papers
Processing of Extended Release Tablets Containing Carbopol® 971P NF Polymer by Top-Drive High Shear. To evaluate the aqueous granulation process in a pilot- ...Read more
formation-and-characterization-of-carbopol-971p-pvp- ...
Journal of Advanced Pharmacy Education and Research
https://japer.in › storage › models › article › for...
Journal of Advanced Pharmacy Education and Research
https://japer.in › storage › models › article › for...
PDF
Carbopol discs showed release in between them. It is postulated that lightly cross- linked polymer Carbopol 971P has a “fishnet” gel structure upon hydration.Read more
8 pages
CARBOPOL ® - LUBRIZOL
IMCD Spain
https://www.imcd.es › tradename › carbopol
IMCD Spain
https://www.imcd.es › tradename › carbopol
Carbopol® polymers are high molecular weight, crosslinked polyacrylic acid polymers. However, these gel forming polymers differ by their chemical crosslinking.Read more


