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    An AI Overview is not available for this searchCan't generate an AI overview right now. Try again later.
    AI Overview
    R422B (often sold under the brand NU-22) is a popular, lower-GWP (Global Warming Potential) retrofit refrigerant used as a "drop-in" replacement for R22 in HVAC systems, featuring zero ozone depletion. Several suppliers offer it, with many promoting it as an "eco-friendly" or "sustainable" alternative due to its efficiency and compatibility with existing mineral oils. 
    Here are key suppliers for R422B refrigerant in 2026: 
    Key Suppliers & Retailers 
    • Royal Refrigerants: Lists 25 lb cylinders of American-branded R422B as a sustainable solution, noting its high-purity composition.
    • CoolmateGas: Stocks 25 lb cylinders of R-422B (NU-22) and offers quick shipping.
    • Refrigerant Center INC: Offers 25 lb, 100% virgin factory-sealed cylinders, suitable for R22 retrofits.
    • eRefrigerants.com: Supplies R-422B (NU-22) in 25 lb cylinders, noting compatibility with existing mineral oil, though they may have restrictions on shipping to certain states.
    • BudgetHeating.com: Offers both 25 lb jugs and smaller 28oz canisters of R422B for smaller repairs.
    • Uri.com (URI): Stocks 25 lb and larger cylinders (up to 110 lb) of R422B. 
    Key Features of R422B 
    • Eco-Friendly Aspects: While R422B is an HFC blend, it does not deplete the ozone layer.
    • Retrofit Friendly: It is designed to work with existing mineral oil, alkylbenzene, or POE oils, which reduces the labor and cost involved in retrofitting.
    • Application: Ideal for residential and commercial air conditioning and non-flooded evaporator chillers.
    • Safety: Classified as A1 (low toxicity and non-flammable). 
    Purchasing Considerations 
    • Licensing: While some suppliers permit purchasing without a license via a disclaimer, many R422B products are for certified HVAC professionals only.
    • Shipping: These products are often shipped as hazardous materials (HazMat) via ground freight.
    • Availability: Some regions, specifically California and New York, may have restrictions on certain refrigerant purchases. 
    Disclaimer: Always confirm with the supplier regarding compliance with local environmental regulations and licensing requirements before purchase. 
    • R422B Refrigerant for Sale | Eco-Friendly Cooling | Buy Now
      Default Title - $295.00 Add to Cart. R-422B 25 lb (NU22) Refrigerant AMERICAN BRANDED New Factory Sealed Cylinder- USA Brand, High...
      Royal Refrigerants
    • Freon Refrigerant - R422B - 28oz canister (R22 replacement)
      You save $76.00! ... NO FLUSH NEEDED!!! ... R422B can be used to COMPLETELY replace R-22 refrigerant in new or existing R-22 resid...
      Budget Heating and Air Conditioning
    • R422B Refrigerant 25lb Cylinder Tank - Reliable HVAC ...
      Description. R422B is a hydrofluorocarbon (HFC) refrigerant blend designed as a drop-in replacement for R22 in air conditioning an...
      Jackson Systems
    Show all
    • R422B Refrigerant for Sale | Eco-Friendly Cooling | Buy Now
      Default Title - $295.00 Add to Cart. R-422B 25 lb (NU22) Refrigerant AMERICAN BRANDED New Factory Sealed Cylinder- USA Brand, High...
      Royal Refrigerants
    • Freon Refrigerant - R422B - 28oz canister (R22 replacement)
      You save $76.00! ... NO FLUSH NEEDED!!! ... R422B can be used to COMPLETELY replace R-22 refrigerant in new or existing R-22 resid...
      Budget Heating and Air Conditioning
    • R422B Refrigerant 25lb Cylinder Tank - Reliable HVAC ...
      Description. R422B is a hydrofluorocarbon (HFC) refrigerant blend designed as a drop-in replacement for R22 in air conditioning an...
      Jackson Systems
    • R-422B (NU-22) Refrigerant 25 LB - CoolmateGas
      CoolmateGas stocks a large amount of R410A, R134A, R22, 407C, and 404A. ... R422B is a hydrochlorofluorocarbon (HCFC) refrigerant ...
      CoolmateGas
    • Shop R422B Refrigerants - URI
      25R422B. $ 734.50. R422B refrigerant, HFC blends, 25 lb cylinder. × Set Quantity & Add to Cart. 25R422B. Quantity. 25R422BNRI. $ 1...
      United Refrigeration Inc.
    • Wholesale R422B Refrigerant – 25lb Cylinders for Universal R22 ...
      Wholesale R422B Refrigerant – 25lb Cylinders for Universal R22 Replacement in Commercial Systems (5 Cylinders / 125lb Total) ... T...
      AirRefrigerant
    • Disposable NU-22B (R422B) 25 lb. Cylinder - Best Price
      When you need an effective and straightforward way to service older R22 systems, Refrigerant Guys' R422B is the ideal retrofit sol...
      Refrigerant Guys
    • R-422B 25 lb (NU22) Refrigerant: The Ideal R-22 Replacement for HVAC ...
      May 19, 2025 — ✅ Efficient Cooling Performance – Provides cooling capacity similar to R-22. ✅ No Oil Change Required – Compatible with mineral oi...
      Royal Refrigerants
    • Go to product viewer dialog for this item.
      R-422B (NU-22) Refrigerant 25 LB| CoolmateGas Refrigerant
      R422B is a hydrochlorofluorocarbon (HCFC) refrigerant blend that is commonly used as a replacement for R22 in various air conditio...
      Google
    • Go to product viewer dialog for this item.
      R-422B (NU-22) Refrigerant 25 lb. 1 Cylinder
      This item is ineligible for sale or shipping to CA/NY. R-422B (NU-22) Refrigerant 25 lb. (total weight: 33 lb.) Free Continental U...
      Google
    • Go to product viewer dialog for this item.
      Freon Refrigerant R422B 28oz Canister
      NO FLUSH NEEDED!!! IF YOU HAVE A SYSTEM RUNNING ON R22 THIS IS THE EASY WAY TO SWITCH ON ECO-FRIENDLY REFRIGERANT-NO RETROFIT REQU...
      Google
    • Go to product viewer dialog for this item.
      R-422B (Nu-22) Refrigerant 25 LB Online
      Purchase R-422B (Nu-22) Refrigerant 25 LB online from Refrigerant Center INC. Find top-quality refrigerants for your needs. Order ...
      Google
    • Go to product viewer dialog for this item.
      R-422B (NU-22) Refrigerant 25 LB|CoolmateGas Refrigerant, 1 Cylinder
      R-422B (NU-22) Refrigerant 25 LB In Great Price If you don't have license, you may simply fill out the disclaimer(the form link be...
      Google
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    R422B Refrigerant for Sale | Eco-Friendly Cooling | Buy Now


    Royal Refrigerants
    https://royalrefrigerants.com › collections
    Royal Refrigerants
    https://royalrefrigerants.com › collections
    Find R422B refrigerant for sale at unbeatable prices! Perfect for eco-conscious cooling systems. Buy R422B refrigerant online today with fast, free shipping.
    R422B Refrigerant gas Eco-Friendly Supplier from royalrefrigerants.com
    Free delivery · 30-day returns
    Missing: gas ‎Supplier

    Freon Refrigerant R422B, 25lb. Jug (R22 Replacement)


    Budget Heating and Air Conditioning
    https://www.budgetheating.com › ... › 20lb - 30lb JUGS
    Budget Heating and Air Conditioning
    https://www.budgetheating.com › ... › 20lb - 30lb JUGS
    R422B can be used to COMPLETELY replace R-22 refrigerant in new or existing R-22 residential and commercial air conditioning systems as well as non-flooded ...Read more
    R422B Refrigerant gas Eco-Friendly Supplier from www.budgetheating.com
    $399.00 · In stock · 5.0(1) · $29.10 delivery · 30-day returns
    Missing: Supplier ‎| Show results with: Supplier

    R-422B


    iGas USA
    https://www.igasusa.com › products › refrigerants
    iGas USA
    https://www.igasusa.com › products › refrigerants
    R-422B is a non-ozone-depleting refrigerant compatible with all standard oils, equipment components, and materials used in R-22 systems. Safety Data Sheet ...Read more
    R422B Refrigerant gas Eco-Friendly Supplier from www.igasusa.com

    R-422B (NU-22) Refrigerant 25 LB


    CoolmateGas
    https://coolmategas.com › products › r-422b-nu-22-refr...
    CoolmateGas
    https://coolmategas.com › products › r-422b-nu-22-refr...
    R422B is often used as a retrofit refrigerant for existing R22 systems, providing a more environmentally friendly alternative while maintaining good performance ...Read more
    R422B Refrigerant gas Eco-Friendly Supplier from coolmategas.com
    $395.95 to $11,400.00 · In stock · 5.0(486) · Free delivery · 30-day returns
    Missing: Eco- ‎Supplier

    Buy R422B Refrigerant Online


    refrigerantinc.com
    https://www.refrigerantinc.com › products › r422b-refri...
    refrigerantinc.com
    https://www.refrigerantinc.com › products › r422b-refri...
    Environmentally Friendly: R422B has a lower Global Warming Potential (GWP) compared to traditional refrigerants. Compatibility: Easily retrofitted in existing R ...Read more
    R422B Refrigerant gas Eco-Friendly Supplier from www.refrigerantinc.com
    $369.00
    Missing: gas ‎Supplier

    R-422B Refrigerant | Retrofit Solution for R-22


    Weitron
    https://weitron.com › product
    Weitron
    https://weitron.com › product
    R-422B is a non-ozone depleting R-22 retrofit with matching cooling capacity and lower operating pressure. It does not require oil change.Read more
    R422B Refrigerant gas Eco-Friendly Supplier from weitron.com
    Missing: R422B ‎| Show results with: R422B

    Refrigerant Products | R422B | HFC


    National Refrigerants, Inc.
    https://refrigerants.com › product › r422b
    National Refrigerants, Inc.
    https://refrigerants.com › product › r422b
    R422B is a retrofit blend that is designed to match R22 in air conditioning applications. Available in 25 and 110 lb. cylinders.
    Missing: gas ‎Eco- ‎Friendly

    Refrigerant Supplier | HVAC Bulk Wholesale & Delivery ...


    AirRefrigerant
    https://airrefrigerant.com
    AirRefrigerant
    https://airrefrigerant.com
    AirRefrigerant™ is a trusted bulk refrigerant supplier, offering wholesale pricing on Freon and refrigerant gases, including R22, R410A, R32, R407C, and more.Read more

    Shop R422B Refrigerants


    United Refrigeration Inc.
    https://www.uri.com › refrigerants › gases › r422b
    United Refrigeration Inc.
    https://www.uri.com › refrigerants › gases › r422b
    Shop our extensive supply of R422B Refrigerants. URI carries National Refrigerants and more.
    R422B Refrigerant gas Eco-Friendly Supplier from www.uri.com
    5.0 store rating (12)
    Missing: Friendly ‎| Show results with: Friendly

    Wholesale & Bulk HFC Refrigerants Gas| R410A, R134A, R32 ...


    taninrefrigerant.com
    https://www.taninrefrigerant.com › category › hfc
    taninrefrigerant.com
    https://www.taninrefrigerant.com › category › hfc
    Buy HFC refrigerants in bulk, including R410A, R134A, R32, R407C, and more. Fast, factory-direct supply from a USA-based HFC refrigerant supplier.
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    • Rgas Refrigerant: R-422B, HFC, A1, 25 lb Cylinder, Gray Model: R422B25.
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    • R422B, a.k.a. NU22, Refrigerant 22 oz. Can R22 Drop-In Replacement, Fast Shipping & IN STOCK!.
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      Total Parts USA
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    • R-422B (NU-22) Refrigerant 25 LB| CoolmateGas Refrigerant.
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      frosty-freezeacproducts.com
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      frosty-freezeacproducts.com
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